Chfr | checkpoint with forkhead and ring finger domains

GeneMGI:2444898Genome BrowserSynonyms: 5730484M20Rik, RNF116

Physiological systems

22 / 24 physiological systems tested

11 Significantly impacted by the knock-out

 Reproductive system Integument Immune system Homeostasis/metabolism Hematopoietic system Respiratory system Endocrine/exocrine gland Pigmentation Renal/urinary system Cardiovascular system Growth/size/body region

11 No significant impact

2 Not tested

Gene metrics:12Significant phenotypes
0Associated diseases
Expression examined in:78Adult tissues
27Embryo tissues

Phenotypes

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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Human diseases caused by Chfr mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.






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Histopathology

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IMPC related publications

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Order Mouse and ES Cells

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