Gene Summary

Name:
neuronal growth regulator 1
Synonyms:
Ntra,  5330422G01Rik,  neurotractin

IMPC Data Collections

IMPC Phenotype Summary

Significant
Not Significant
Not tested

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

Phenotype System Allele Zyg Sex Life Stage P Value
abnormal heart morphology Negr1tm1b(KOMP)Wtsi HOM Early adult 0.00
abnormal eye morphology Negr1tm1b(KOMP)Wtsi HOM Early adult 0.00
decreased bone mineral density Negr1tm1b(KOMP)Wtsi HOM Early adult 5.76×10-05
enlarged heart Negr1tm1b(KOMP)Wtsi HOM Early adult 0.00
decreased brain weight Negr1tm1b(KOMP)Wtsi HOM   Early adult 2.77×10-06
hyperactivity Negr1tm1b(KOMP)Wtsi HOM Early adult 1.36×10-08
abnormal behavior Negr1tm1b(KOMP)Wtsi HOM Early adult 2.73×10-18
decreased bone mineral content Negr1tm1b(KOMP)Wtsi HOM Early adult 5.49×10-05
decreased grip strength Negr1tm1b(KOMP)Wtsi HOM   Early adult 1.87×10-07
decreased thigmotaxis Negr1tm1b(KOMP)Wtsi HOM Early adult 2.73×10-18

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

lacZ Expression

An assay measuring the expression of lacZ shows the tissue where the gene is expressed.

Anatomy Images Zygosity Mutant Expr
Adrenal gland  Section images heterozygote 50% (1 of 2)
Cecum  Section images heterozygote 50% (1 of 2)
Cerebellum  Section images heterozygote 100% (2 of 2)
Colon  Section images heterozygote 50% (1 of 2)
Duodenum  Section images heterozygote 50% (1 of 2)
Epididymis  Section images heterozygote 50% (1 of 2)
Eye  Section images heterozygote 100% (2 of 2)
Ileum  Section images heterozygote 100% (2 of 2)
Kidney  Section images heterozygote 100% (2 of 2)
Midbrain  Section images heterozygote 100% (2 of 2)
Olfactory lobe  Section images heterozygote 100% (2 of 2)
Oviduct  Section images heterozygote 50% (1 of 2)
Prostate gland  Section images heterozygote 50% (1 of 2)
Spinal cord  Section images heterozygote 100% (2 of 2)
Stomach  Section images heterozygote 50% (1 of 2)
Testis  Section images heterozygote 50% (1 of 2)
Trigeminal V nerve  Section images heterozygote 100% (2 of 2)
Uterus  Section images heterozygote 50% (1 of 2)
Vas deferens  Section images heterozygote 50% (1 of 2)
Aorta N/A heterozygote 0.0% (0 of 2)
Blood N/A heterozygote 0.0% (0 of 2)
Bone marrow N/A heterozygote 0.0% (0 of 2)
Brain N/A heterozygote Not available
Brainstem N/A heterozygote Not available
Brown adipose tissue N/A heterozygote 0.0% (0 of 2)
Cartilage tissue N/A heterozygote Not available
Cerebral cortex N/A heterozygote Not available
Chest bone N/A heterozygote Not available
Diaphragm N/A heterozygote 0.0% (0 of 2)
Esophagus N/A heterozygote 0.0% (0 of 2)
Gall bladder N/A heterozygote Not available
Gonadal fat pad N/A heterozygote 0.0% (0 of 2)
Harderian gland N/A heterozygote 0.0% (0 of 2)
Heart N/A heterozygote Not available
Hindlimb N/A heterozygote Not available
Hippocampus N/A heterozygote Not available
Hypothalamus N/A heterozygote Not available
Jejunum N/A heterozygote 0.0% (0 of 2)
Large intestine N/A heterozygote Not available
Liver N/A heterozygote 0.0% (0 of 2)
Lower urinary tract N/A heterozygote Not available
Lung N/A heterozygote 0.0% (0 of 2)
Lymph node N/A heterozygote Not available
Mammary gland N/A heterozygote 0.0% (0 of 2)
Mesenteric adipose tissue N/A heterozygote 0.0% (0 of 2)
Mesenteric lymph node N/A heterozygote 0.0% (0 of 2)
Ovary N/A heterozygote 0.0% (0 of 2)
Pancreas N/A heterozygote 0.0% (0 of 2)
Parathyroid gland N/A heterozygote 0.0% (0 of 2)
Parotid gland N/A heterozygote 0.0% (0 of 2)
Penis N/A heterozygote 0.0% (0 of 2)
Peripheral nervous system N/A heterozygote Not available
Peyer's patch N/A heterozygote Not available
Pituitary gland N/A heterozygote 0.0% (0 of 2)
Quadriceps N/A heterozygote 0.0% (0 of 2)
Sciatic nerve N/A heterozygote 0.0% (0 of 2)
Skeletal muscle N/A heterozygote Not available
Skin N/A heterozygote 0.0% (0 of 2)
Small intestine N/A heterozygote Not available
Spleen N/A heterozygote 0.0% (0 of 2)
Stomach pyloric region N/A heterozygote Not available
Striatum N/A heterozygote Not available
Sublingual gland N/A heterozygote 0.0% (0 of 2)
Submandibular gland N/A heterozygote 0.0% (0 of 2)
Thymus N/A heterozygote 0.0% (0 of 2)
Thyroid gland N/A heterozygote 0.0% (0 of 2)
Tongue N/A heterozygote 0.0% (0 of 2)
Trachea N/A heterozygote 0.0% (0 of 2)
Urinary bladder N/A heterozygote 0.0% (0 of 2)
Vagina N/A heterozygote 0.0% (0 of 2)
Vascular system N/A heterozygote Not available
Vesicular gland N/A heterozygote 0.0% (0 of 2)
White adipose tissue N/A heterozygote Not available
No Embryo expression data was found for this gene.

Background staining occurs in wild type mice and embryos at an incidental rate.

Anatomy Background staining in controls (WT)
adrenal gland 0.68% (4 of 584)
aorta 0.17% (1 of 584)
blood 0.0%
bone marrow 0.0%
brain 0.68% (4 of 584)
brainstem 0.34% (2 of 584)
brown adipose tissue 0.0%
cartilage tissue 0.17% (1 of 584)
cecum 2.97% (11 of 370)
cerebellum 0.51% (3 of 584)
cerebral cortex 0.34% (2 of 584)
chest bone Unavailable
colon 8.73% (11 of 126)
diaphragm 0.0%
duodenum 0.79% (1 of 126)
epididymis 12.78% (17 of 133)
esophagus 1.72% (7 of 408)
eye 0.0%
gall bladder 0.0%
gonadal fat pad 0.0%
harderian gland 0.0%
heart 0.34% (2 of 584)
hindlimb 0.0%
hippocampus 0.51% (3 of 584)
hypothalamus 0.34% (2 of 584)
ileum 10.32% (13 of 126)
jejunum 3.97% (5 of 126)
kidney 3.6% (21 of 584)
large intestine 1.71% (10 of 584)
liver 0.0%
lower urinary tract 0.17% (1 of 584)
lung 0.34% (2 of 584)
lymph node 0.17% (1 of 584)
mammary gland 0.0%
mesenteric adipose tissue 0.0%
mesenteric lymph node 0.0%
midbrain 0.0%
olfactory lobe 0.34% (2 of 584)
ovary 0.17% (1 of 584)
oviduct 0.0%
pancreas 0.86% (5 of 584)
parathyroid gland 0.18% (1 of 562)
parotid gland 0.0%
penis 0.0%
peripheral nervous system 0.34% (2 of 584)
peyers patch 0.0%
pituitary gland 0.17% (1 of 584)
prostate gland 2.05% (12 of 584)
quadriceps 0.0%
sciatic nerve 0.0%
skeletal muscle 0.0%
skin 0.17% (1 of 584)
small intestine 1.54% (9 of 584)
spinal cord 0.51% (3 of 584)
spleen 0.51% (3 of 584)
stomach 2.05% (12 of 584)
stomach pyloric region 0.0%
striatum 0.51% (3 of 584)
sublingual gland 0.0%
submandibular gland 1.53% (2 of 131)
testis 1.03% (6 of 584)
thymus 0.17% (1 of 584)
thyroid gland 2.74% (16 of 584)
tongue 3.97% (5 of 126)
trachea 0.51% (3 of 584)
trigeminal v nerve 0.0%
urinary bladder 0.0%
uterus 0.0%
vagina 0.0%
vas deferens 3.67% (14 of 381)
vascular system 0.0%
vesicular gland 0.0%
white adipose tissue 0.0%
No Embryo expression data was found for this gene.

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

X-ray

XRay Images Whole Body Dorso Ventral

10 Images

X-ray

XRay Images Whole Body Lateral Orientation

10 Images

Adult LacZ

LacZ Images Section

44 Images

Human diseases caused by Negr1 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Negr1 by phenotypic similarity.

Disease Similarity of
phenotypes
Matching phenotypes Source
Intellectual Developmental Disorder, X-Linked, Syndromic, Houge Type
Impulsivity, Attention deficit hyperactivity disorder, Hyperactivity OMIM:301008
Obesity
Increased waist to hip ratio, Decreased resting energy expenditure, Obesity OMIM:601665
Intellectual Developmental Disorder, X-Linked 109
Impulsivity, Aggressive behavior, Hyperactivity OMIM:309548
Mental Retardation, Autosomal Dominant 52
Anxiety, Hyperactivity OMIM:617796
Attention Deficit-Hyperactivity Disorder
Attention deficit hyperactivity disorder, Hyperactivity OMIM:143465
Ethanolaminosis
Cardiomegaly OMIM:227150
Mental Retardation, Autosomal Dominant 45
Attention deficit hyperactivity disorder, Hyperactivity OMIM:617600
Spastic Tetraplegia, Thin Corpus Callosum, And Progressive Microcephaly
Inability to walk, Irritability, Hyperactivity OMIM:616657
Mental Retardation, Autosomal Recessive 37
Aggressive behavior, Hyperactivity OMIM:615493
Ank3-Related Intellectual Disability-Sleep Disturbance Syndrome
Aggressive behavior, Hyperactivity ORPHA:356996
Insulin-Like Growth Factor I Deficiency
Osteopenia, Hyperactivity OMIM:608747
Mental Retardation, Autosomal Recessive 3
Hyperactivity OMIM:608443
Mental Retardation, Autosomal Recessive 54
Hyperactivity OMIM:617028
Schizophrenia 15
Hyperactivity OMIM:613950
22q13 deletion syndrome (Phelan-Mcdermid syndrome)
Hyperactivity DECIPHER:20
Potocki-Lupski syndrome (17p11.2 duplication syndrome)
Hyperactivity DECIPHER:19
Immunodeficiency 8
Hyperactivity OMIM:615401
8p23.1 deletion syndrome
Atrioventricular canal defect, Atrial septal defect, Hyperactivity, Abnormal heart morphology DECIPHER:39
Mental Retardation, Autosomal Dominant 33
Hyperactivity OMIM:616311
Mucopolysaccharidosis, Type Iiib
Asymmetric septal hypertrophy, Aggressive behavior, Dense calvaria, Hepatomegaly, Joint stiffness... OMIM:252920
Glycine Encephalopathy
Lethargy, Aggressive behavior, Impulsivity, Irritability, Hyperactivity OMIM:605899
Smith-Magenis syndrome
Self-mutilation, Hyperactivity DECIPHER:8
Developmental And Epileptic Encephalopathy 43
Ataxia, Hyperactivity OMIM:617113
Microcephaly 2, Primary, Autosomal Recessive, With Or Without Cortical Malformations
Impulsivity, Aggressive behavior, Hyperactivity OMIM:604317
Juvenile Huntington Disease
Dystonia, Gait ataxia, Depression, Ataxia, Bradykinesia, Progressive cerebellar ataxia, Irritabil... ORPHA:248111
Intellectual Disability-Expressive Aphasia-Facial Dysmorphism Syndrome
Hyperactivity ORPHA:436151
Obesity-Colitis-Hypothyroidism-Cardiac Hypertrophy-Developmental Delay Syndrome
Craniosynostosis, Cardiomegaly ORPHA:88643
Phenylketonuria
Self-mutilation, Aggressive behavior, Depression, Irritability, Anxiety, Hyperactivity, Attention... OMIM:261600
Intellectual Developmental Disorder, X-Linked 72
Hyperactivity OMIM:300271
Mental Retardation, Autosomal Dominant 43
Impulsivity, Anxiety, Hyperactivity OMIM:616977
Fraxe Intellectual Disability
Impulsivity, Aggressive behavior, Hyperactivity ORPHA:100973
Microcephaly, Seizures, And Developmental Delay
Ataxia, Hyperactivity OMIM:613402
Hyperprolinemia, Type I
Aggressive behavior, Ataxia, Hyperactivity OMIM:239500
X-Linked Intellectual Disability-Psychosis-Macroorchidism Syndrome
Bipolar affective disorder, Aggressive behavior, Broad-based gait, Irritability, Abnormal fear/an... ORPHA:3077
Chromosome 3Q29 Deletion Syndrome
Anxiety, Gait ataxia, Aggressive behavior, Hyperactivity OMIM:609425
Ck Syndrome
Joint hypermobility, Aggressive behavior, Abnormal cortical bone morphology, Irritability, Hypera... OMIM:300831
Mannosidosis, Beta A, Lysosomal
Aggressive behavior, Hyperactivity OMIM:248510
Intellectual Developmental Disorder, X-Linked 104
Aggressive behavior, Ataxia, Hyperactivity OMIM:300983
Coffin-Siris Syndrome 8
Self-injurious behavior, Aggressive behavior, Hyperactivity OMIM:618362
Landau-Kleffner Syndrome
Gait ataxia, Aggressive behavior, Depression, Emotional lability, Impulsivity, Anxiety, Hyperacti... ORPHA:98818
Encephalopathy, Progressive, With Or Without Lipodystrophy
Hepatomegaly, Dystonia, Ataxia, Hyperactivity OMIM:615924
Xq25 Microduplication Syndrome
Anxiety, Hyperactivity ORPHA:521258
Xq25 Duplication Syndrome
Anxiety, Hyperactivity OMIM:300979
Lennox-Gastaut Syndrome
Personality disorder, Falls, Aggressive behavior, Hyperactivity ORPHA:2382
Infantile Sialic Acid Storage Disease
Hepatomegaly, Osteopenia, Cardiomegaly, Splenomegaly OMIM:269920
Neurodevelopmental Disorder With Epilepsy And Hypoplasia Of The Corpus Callosum
Inability to walk, Gait disturbance, Dysmetria, Hyperactivity OMIM:618090
Coffin-Siris Syndrome 7
Hyperactivity, Abnormal cardiac septum morphology, Abnormal heart morphology, Sagittal craniosyno... OMIM:618027
Autism Spectrum Disorder Due To Auts2 Deficiency
Arthrogryposis multiplex congenita, Atrial septal defect, Abnormal heart morphology, Joint contra... ORPHA:352490
Intellectual Developmental Disorder, X-Linked 101
Hyperactivity OMIM:300928
Beck-Fahrner Syndrome
Joint hypermobility, Ventricular septal defect, Depression, Cardiomegaly, Anxiety, Attention defi... OMIM:618798
Intellectual Developmental Disorder, X-Linked 30
Anxiety, Aggressive behavior, Hyperactivity OMIM:300558
Sotos Syndrome 3
Hyperactivity OMIM:617169
Mental Retardation, Autosomal Recessive 39
Aggressive behavior, Hyperactivity OMIM:615541
Hyperphosphatasia With Mental Retardation Syndrome 6
Aggressive behavior, Flexion contracture, Hip contracture, Knee flexion contracture, Hyperactivit... OMIM:616809
Neuraminidase Deficiency
Epiphyseal stippling, Hepatomegaly, Cardiomegaly, Dysmetria, Splenomegaly, Cardiomyopathy OMIM:256550
Intellectual Developmental Disorder, X-Linked, Syndromic 32
Contractures of the large joints, Cardiomegaly OMIM:300886
Neurodegeneration With Ataxia And Late-Onset Optic Atrophy
Gait ataxia, Truncal ataxia, Depression, Limb ataxia, Gait disturbance, Ataxia, Unsteady gait, Ca... OMIM:619259
Ck Syndrome
Joint hypermobility, Irritability, Aggressive behavior, Hyperactivity ORPHA:251383
Language Delay And Attention Deficit-Hyperactivity Disorder/Cognitive Impairment With Or Without Cardiac Arrhythmia
Attention deficit hyperactivity disorder, Hyperactivity OMIM:617182
Combined Oxidative Phosphorylation Deficiency 33
Hepatomegaly, Left ventricular hypertrophy, Cardiomegaly, Cardiomyopathy OMIM:617713
Carnitine Deficiency, Systemic Primary
Lethargy, Endocardial fibroelastosis, Hepatomegaly, Cardiomegaly, Hypertrophic cardiomyopathy OMIM:212140
Mulibrey Nanism
Myocardial fibrosis, Hepatomegaly, Cardiomegaly, Pericardial constriction, Thickened cortex of lo... OMIM:253250
Succinic Semialdehyde Dehydrogenase Deficiency
Aggressive behavior, Self-injurious behavior, Ataxia, Anxiety, Hyperactivity OMIM:271980
Myopathy, Congenital, With Structured Cores And Z-Line Abnormalities
Cardiomegaly OMIM:618654
Mucopolysaccharidosis, Type Iiia
Asymmetric septal hypertrophy, Dense calvaria, Hepatomegaly, Joint stiffness, Splenomegaly, Hyper... OMIM:252900
Carnitine Palmitoyltransferase Ii Deficiency, Infantile
Hepatomegaly, Lethargy, Dilated cardiomyopathy, Cardiomegaly OMIM:600649
Mitochondrial Complex Iv Deficiency, Nuclear Type 20
Hepatomegaly, Lethargy, Cardiomegaly OMIM:619064
Autosomal Recessive Non-Syndromic Intellectual Disability
Hyperactivity, Dystonia, Impulsivity, Depression ORPHA:88616
Intellectual Developmental Disorder, X-Linked 107
Hyperactivity OMIM:301013
Symptomatic Form Of Hemochromatosis Type 1
Osteoporosis, Lethargy, Apathy, Stiff interphalangeal joints, Hepatomegaly, Joint stiffness, Card... ORPHA:465508
Angelman Syndrome Due To Imprinting Defect In 15Q11-Q13
Inappropriate laughter, Ataxia, Happy demeanor, Hyperactivity, Broad-based gait ORPHA:411515
Clcn4-Related X-Linked Intellectual Disability Syndrome
Bipolar affective disorder, Aggressive behavior, Depression, Self-injurious behavior, Progressive... ORPHA:485350
X-Linked Intellectual Disability-Hypotonia-Movement Disorder Syndrome
Hyperactivity, Joint laxity, Broad-based gait, Aggressive behavior ORPHA:457260
Intellectual Developmental Disorder With Abnormal Behavior, Microcephaly, And Short Stature
Aggressive behavior, Hyperactivity OMIM:618342
Cantu Syndrome
Osteoporosis, Pericardial effusion, Congenital hypertrophy of left ventricle, Cardiomegaly, Bicus... OMIM:239850
Dystonia, Dopa-Responsive, Due To Sepiapterin Reductase Deficiency
Dystonia, Aggressive behavior, Ataxia, Hyperactivity OMIM:612716
Hemochromatosis, Type 1
Osteoporosis, Hepatomegaly, Cardiomegaly, Splenomegaly, Cardiomyopathy OMIM:235200
Ectodermal Dysplasia-Syndactyly Syndrome 2
Cardiomegaly OMIM:613576
Dihydropyrimidine Dehydrogenase Deficiency
Lethargy, Hyperactivity OMIM:274270
X-Linked Intellectual Disability-Cardiomegaly-Congestive Heart Failure Syndrome
Inability to walk, Steppage gait, Abnormal atrioventricular valve morphology, Aortic valve stenos... ORPHA:324410
Gand Syndrome
Inappropriate laughter, Hyperactivity OMIM:615074
Mental Retardation, Autosomal Recessive 61
Aggressive behavior, Hyperactivity OMIM:617773
Neurodevelopmental Disorder With Behavioral Abnormalities, Absent Speech, And Hypotonia
Inability to walk, Paroxysmal bursts of laughter, Self-injurious behavior, Hyperactivity OMIM:618718
Mitochondrial Complex Iv Deficiency, Nuclear Type 7
Ventricular hypertrophy, Truncal ataxia, Limb ataxia, Cardiomegaly, Hypertrophic cardiomyopathy OMIM:619051
Cln5 Disease
Dysdiadochokinesis, Inability to walk, Truncal ataxia, Aggressive behavior, Ataxia, Unsteady gait... ORPHA:228360
Guanidinoacetate Methyltransferase Deficiency
Dystonia, Aggressive behavior, Self-injurious behavior, Ataxia, Hyperactivity, Athetosis ORPHA:382
Female Restricted Epilepsy With Intellectual Disability
Anxiety, Impulsivity, Aggressive behavior, Hyperactivity ORPHA:101039
Medium Chain Acyl-Coa Dehydrogenase Deficiency
Lethargy, Ataxia, Hepatomegaly, Distal arthrogryposis, Cardiomegaly ORPHA:42
Attrv30M Amyloidosis
Cardiomegaly, Cardiomyopathy ORPHA:85447
Osteochondrodysplasia, Complex Lethal, Symoens-Barnes-Gistelinck Type
Ventricular septal defect, Flexion contracture, Fractured radius, Multiple prenatal fractures, Ca... OMIM:616897
Symptomatic Form Of Fragile X Syndrome In Female Carrier
Joint laxity, Aggressive behavior, Depression, Self-injurious behavior, Irritability, Anxiety, Hy... ORPHA:449291
Hsd10 Disease, Infantile Type
Dystonia, Loss of ability to walk, Paroxysmal bursts of laughter, Cardiomegaly, Hypertrophic card... ORPHA:391428
Chromosome 15Q25 Deletion Syndrome
Dextrocardia, Abnormal cardiac septum morphology, Attention deficit hyperactivity disorder, Hyper... OMIM:614294
Mental Retardation, Autosomal Recessive 38
Self-mutilation, Unsteady gait, Aggressive behavior, Hyperactivity OMIM:615516
Inverted Duplicated Chromosome 15 Syndrome
Joint hypermobility, Aggressive behavior, Ventricular septal defect, Self-biting, Hyperactivity, ... ORPHA:3306
Intellectual Developmental Disorder, X-Linked, Syndromic, Snijders Blok Type
Hyperactivity, Aggressive behavior, Broad-based gait, Dysplastic pulmonary valve OMIM:300958
Childhood-Onset Motor And Cognitive Regression Syndrome With Extrapyramidal Movement Disorder
Inability to walk, Dystonia, Gait ataxia, Aggressive behavior, Impulsivity, Hyperactivity ORPHA:500180
Clark-Baraitser Syndrome
Aggressive behavior, Hyperactivity OMIM:617752
Congenital Toxoplasmosis
Hepatomegaly, Cardiomegaly ORPHA:858
Fragile X Syndrome
Mitral valve prolapse, Joint laxity, Hyperactivity OMIM:300624
Neurodevelopmental Disorder With Movement Abnormalities, Abnormal Gait, And Autistic Features
Hyperactivity, Unsteady gait, Broad-based gait, Happy demeanor OMIM:617865
Timothy Syndrome
Patent foramen ovale, Tetralogy of Fallot, Cardiomegaly, Ventricular septal defect OMIM:601005
Intellectual Developmental Disorder, X-Linked 21
Joint hypermobility, Impulsivity, Hyperactivity OMIM:300143
Carnitine Palmitoyltransferase I Deficiency
Hepatomegaly, Lethargy, Cardiomegaly OMIM:255120
Cardiomyopathy, Familial Hypertrophic, 4
Ventricular hypertrophy, Pericardial effusion, Hepatomegaly, Cardiomegaly, Ventricular septal hyp... OMIM:115197
Familial Atrial Myxoma
Pulmonic valve myxoma, Cardiomegaly, Cardiac myxoma, Bacterial endocarditis ORPHA:615
Mitochondrial Complex I Deficiency, Nuclear Type 36
Perimembranous ventricular septal defect, Cardiomegaly OMIM:619170
Mucopolysaccharidosis, Type Iiic
Asymmetric septal hypertrophy, Dense calvaria, Hepatomegaly, Joint stiffness, Splenomegaly, Hyper... OMIM:252930
Intellectual Developmental Disorder, Autosomal Recessive 71
Hyperactivity, Attention deficit hyperactivity disorder, Ventricular septal defect OMIM:618504
Cardiomyopathy, Familial Hypertrophic 27
Cardiomegaly OMIM:618052
Rasmussen Subacute Encephalitis
Inability to walk, Hemidystonia, Emotional lability, Irritability, Hyperactivity, Attention defic... ORPHA:1929
Refsum Disease, Classic
Ataxia, Cardiomegaly, Cardiomyopathy OMIM:266500
16P12.1P12.3 Triplication Syndrome
Skin-picking, Atrial septal defect, Abnormal heart morphology, Abnormal tricuspid valve morpholog... ORPHA:485405
Congenital Tricuspid Valve Dysplasia
Anomalous pulmonary venous return, Abnormal tricuspid valve leaflet morphology, Pericardial effus... ORPHA:555874
Chromosome 2Q37 Deletion Syndrome
Hyperactivity, Self-injurious behavior, Aggressive behavior, Subvalvular aortic stenosis OMIM:600430
Intellectual Developmental Disorder, X-Linked, Syndromic, Lujan-Fryns Type
Atrial septal defect, Aggressive behavior, Joint laxity, Ventricular septal defect, Flexion contr... OMIM:309520
Gomez-Lopez-Hernandez Syndrome
Bipolar affective disorder, Craniosynostosis, Depression, Self-injurious behavior, Ataxia, Hypera... OMIM:601853
Danon Disease
Myocardial fibrosis, Myocardial necrosis, Cardiomegaly, Dilated cardiomyopathy, Hypertrophic card... OMIM:300257
Neurooculocardiogenitourinary Syndrome
Patent foramen ovale, Atrial septal defect, Cardiomegaly, Ventricular septal defect OMIM:618652
Developmental And Epileptic Encephalopathy 95
Inability to walk, Inappropriate laughter, Arthrogryposis multiplex congenita, Inappropriate cryi... OMIM:618143
Optic Atrophy 11
Dysmetria, Ataxia, Hyperactivity OMIM:617302
Mucopolysaccharidosis Type 3
Disinhibition, Aggressive behavior, Abnormal mitral valve morphology, Craniofacial hyperostosis, ... ORPHA:581
19P13.3 Microduplication Syndrome
Osteoporosis, Ventricular septal defect, Self-injurious behavior, Irritability, Hyperactivity ORPHA:447980
Dysferlin-Related Limb-Girdle Muscular Dystrophy R2
Inability to walk, Limited hip movement, Limited knee flexion/extension, Right ventricular hypert... ORPHA:268
Smith-Magenis Syndrome
Head-banging, Self-mutilation, Hyperactivity, Abnormal heart morphology OMIM:182290
Intellectual Developmental Disorder, X-Linked, Syndromic, Cabezas Type
Gait ataxia, Joint laxity, Aggressive behavior, Hyperactivity, Mood swings OMIM:300354
Infantile Neuroaxonal Dystrophy
Dystonia, Gait disturbance, Flexion contracture, Ataxia, Emotional lability, Unsteady gait, Impul... ORPHA:35069
Alpha-N-Acetylgalactosaminidase Deficiency
Cardiomegaly ORPHA:3137
Lethal Congenital Contracture Syndrome 10
Ventricular septal defect, Torticollis, Cardiomegaly, Overriding aorta, Stiff neck OMIM:617022
Neurodevelopmental Disorder With Brain Abnormalities, Poor Growth, And Dysmorphic Facies
Aggressive behavior, Hyperactivity OMIM:615286
Mental Retardation, X-Linked 77
Hyperactivity OMIM:300454
Amyloidosis, Hereditary, Transthyretin-Related
Ataxia, Cardiomegaly, Cardiomyopathy OMIM:105210
Developmental Delay-Facial Dysmorphism Syndrome Due To Med13L Deficiency
Aggressive behavior, Abnormal heart morphology, Ventricular septal defect, Camptodactyly, Ataxia,... ORPHA:369891
Acyl-Coa Dehydrogenase, Very Long-Chain, Deficiency Of
Hepatomegaly, Lethargy, Cardiomegaly, Hypertrophic cardiomyopathy OMIM:201475
Greenberg Dysplasia
Epiphyseal stippling, Abnormal ossification involving the femoral head and neck, Supernumerary ve... OMIM:215140
X-Linked Creatine Transporter Deficiency
Self-mutilation, Dystonia, Joint hyperflexibility, Ataxia, Hyperactivity, Athetosis ORPHA:52503
Mitochondrial Complex Iii Deficiency, Nuclear Type 7
Aggressive behavior, Hyperactivity OMIM:615824
Mental Retardation, Autosomal Dominant 7
Inappropriate laughter, Gait disturbance, Ataxia, Hyperactivity, Happy demeanor OMIM:614104
Severe Neurodegenerative Syndrome With Lipodystrophy
Gait ataxia, Ataxia, Hepatomegaly, Limb dystonia, Hyperactivity ORPHA:363400
Gaucher Disease, Perinatal Lethal
Arthrogryposis multiplex congenita, Akinesia, Apathy, Hepatomegaly, Cardiomegaly, Splenomegaly, H... OMIM:608013
Neurodevelopmental Disorder With Or Without Autism Or Seizures
Pulmonic stenosis, Atrial septal defect, Hyperactivity OMIM:619239
Graves Disease, Susceptibility To, 1
Irritability, Hyperactivity OMIM:275000
Multiple Joint Dislocations, Short Stature, And Craniofacial Dysmorphism With Or Without Congenital Heart Defects
Osteoporosis, Joint hypermobility, Craniosynostosis, Atrial septal defect, Radioulnar synostosis,... OMIM:245600
X-Linked Adrenoleukodystrophy
Disinhibition, Aggressive behavior, Gait disturbance, Inappropriate sexual behavior, Hyperactivit... ORPHA:43
Adenylosuccinase Deficiency
Self-mutilation, Inability to walk, Inappropriate laughter, Gait ataxia, Aggressive behavior, Hyp... OMIM:103050
Myoclonic-Astatic Epilepsy
Abnormal emotion/affect behavior, Ataxia, Unsteady gait, Hyperactivity, Attention deficit hyperac... ORPHA:1942
Hypertrichotic Osteochondrodysplasia, Cantu Type
Osteoporosis, Abnormal heart valve morphology, Cardiomegaly, Hypertrophic cardiomyopathy ORPHA:1517
Carnitine Palmitoyltransferase Ii Deficiency, Lethal Neonatal
Lethargy, Enlarged kidney, Hepatomegaly, Cardiomegaly, Knee flexion contracture, Dilated cardiomy... OMIM:608836
Alacrimia-Choreoathetosis-Liver Dysfunction Syndrome
Inability to walk, Micronodular cirrhosis, Dystonia, Elevated hepatic transaminase, Microvesicula... ORPHA:404454
Mucopolysaccharidosis, Type Iiid
Asymmetric septal hypertrophy, Flexion contracture, Hepatomegaly, Joint stiffness, Splenomegaly, ... OMIM:252940
Chromosome 10Q26 Deletion Syndrome
Limited elbow extension, Craniosynostosis, Atrial septal defect, Aggressive behavior, Hyperactivi... OMIM:609625
2Q23.1 Microdeletion Syndrome
Paroxysmal bursts of laughter, Self-injurious behavior, Ataxia, Hyperactivity ORPHA:228402
Late Infantile Neuronal Ceroid Lipofuscinosis
Inability to walk, Aggressive behavior, Gait disturbance, Ataxia, Low frustration tolerance, Anxi... ORPHA:168491
Severe Motor And Intellectual Disabilities-Sensorineural Deafness-Dystonia Syndrome
Aggressive behavior, Hyperactivity ORPHA:369939
Complete Atrioventricular Septal Defect
Lethargy, Complete atrioventricular canal defect, Displacement of the papillary muscles, Hepatome... ORPHA:1329
Growth Delay Due To Insulin-Like Growth Factor Type 1 Deficiency
Osteoporosis, Attention deficit hyperactivity disorder, Hyperactivity ORPHA:73272
Marfanoid Habitus-Autosomal Recessive Intellectual Disability Syndrome
Osteopenia, Abnormal bone ossification, Cardiomegaly, Joint hypermobility ORPHA:2463
19P13.12 Microdeletion Syndrome
Arthrogryposis multiplex congenita, Craniosynostosis, Atrial septal defect, Ventricular septal de... ORPHA:254346
Angelman Syndrome Due To Maternal 15Q11Q13 Deletion
Inappropriate laughter, Limitation of movement at ankles, Ataxia, Hyperactivity, Gait imbalance, ... ORPHA:98794
Mend Syndrome
Aortic valve stenosis, Hyperactivity OMIM:300960
Aorta Coarctation
Abnormal left ventricular outflow tract morphology, Aortic valve atresia, Perimembranous ventricu... ORPHA:1457
Spondylometaphyseal Dysplasia, Megarbane-Dagher-Melki Type
Cardiomegaly OMIM:613320
Severe Intellectual Disability-Short Stature-Behavioral Abnormalities-Facial Dysmorphism Syndrome
Irritability, Aggressive behavior, Hyperactivity ORPHA:391307
Fibrosis, Neurodegeneration, And Cerebral Angiomatosis
Hepatomegaly, Dystonia, Irritability, Cardiomegaly OMIM:618278
Cri-Du-Chat Syndrome
Self-mutilation, Aggressive behavior, Difficulty walking, Anxiety, Hyperactivity, Conspicuously h... OMIM:123450
Gaucher Disease, Type Iiic
Mitral valve calcification, Hepatomegaly, Cardiomegaly, Mitral stenosis, Splenomegaly, Aortic val... OMIM:231005
Histiocytosis-Lymphadenopathy Plus Syndrome
Camptodactyly of finger, Atrial septal defect, Flexion contracture of finger, Ventricular septal ... OMIM:602782
Craniofaciofrontodigital Syndrome
Joint hypermobility, Cardiomegaly, Abnormal heart morphology OMIM:114620
Pediatric-Onset Graves Disease
Craniosynostosis, Hepatomegaly, Irritability, Splenomegaly, Hyperactivity, Mood swings ORPHA:525731
Developmental Delay With Variable Intellectual Impairment And Behavioral Abnormalities
Anxiety, Aggressive behavior, Ataxia, Hyperactivity OMIM:618430
Neurodegeneration With Brain Iron Accumulation 2B
Dysdiadochokinesis, Dystonia, Gait ataxia, Bradykinesia, Emotional lability, Impulsivity, Dysmetr... OMIM:610217
Combined Oxidative Phosphorylation Deficiency 41
Cardiomegaly OMIM:618838
Heterotaxy, Visceral, 1, X-Linked
Atrial septal defect, Single ventricle, Ventricular septal defect, Mitral atresia, Dextrocardia, ... OMIM:306955
Hyperlysinemia, Type I
Hyperactivity OMIM:238700
Helsmoortel-Van Der Aa Syndrome
Hyperactivity, Joint laxity, Abnormal heart morphology OMIM:615873
13Q12.3 Microdeletion Syndrome
Self-mutilation, Camptodactyly, Hyperactivity ORPHA:412035
Intellectual Disability-Strabismus Syndrome
Atrial septal defect, Aggressive behavior, Congenital finger flexion contractures, Gait disturban... ORPHA:363528
Hypomagnesemia, Seizures, And Mental Retardation 2
Self-biting, Hyperactivity OMIM:618314
X-Linked Intellectual Disability-Acromegaly-Hyperactivity Syndrome
Aggressive behavior, Hyperactivity ORPHA:85327
Intellectual Disability, Birk-Barel Type
Contractures involving the joints of the feet, Limited elbow flexion/extension, Congenital finger... ORPHA:166108
Severe Intellectual Disability-Poor Language-Strabismus-Grimacing Face-Long Fingers Syndrome
Self-mutilation, Inappropriate laughter, Joint laxity, Low frustration tolerance, Hyperactivity ORPHA:363686
Glass Syndrome
Aggressive behavior, Camptodactyly, Happy demeanor, Hyperactivity, Broad-based gait OMIM:612313
Intellectual Developmental Disorder, X-Linked, Syndromic 34
Atrial septal defect, Joint laxity, Ankylosis, Aggressive behavior, Ventricular septal defect, At... OMIM:300967
Mucopolysaccharidosis Type 2
Aggressive behavior, Hyperactivity, Abnormal tricuspid valve morphology, Hip osteoarthritis, Abno... ORPHA:580
Lamb-Shaffer Syndrome
Fused cervical vertebrae, Ataxia, Hyperactivity ORPHA:530983
Choreoacanthocytosis
Hair-pulling, Emotional lability, Head-banging, Progressive inability to walk, Falls, Hyperactivi... ORPHA:2388
Sandhoff Disease
Hepatomegaly, Hepatosplenomegaly, Cardiomegaly, Ataxia OMIM:268800
Abetalipoproteinemia
Gait ataxia, Steppage gait, Ataxia, Hepatomegaly, Cardiomegaly, Dysmetria, Osteopenia, Broad-base... ORPHA:14
Fucosidosis
Hepatomegaly, Flexion contracture, Cardiomegaly, Splenomegaly OMIM:230000
Mucolipidosis Ii Alpha/Beta
Hepatomegaly, Pathologic fracture, Cardiomegaly, Splenomegaly, Osteopenia, Hypertrophic cardiomyo... OMIM:252500
Bohring-Opitz Syndrome
Bilateral wrist flexion contracture, Inability to walk, Congenital contracture, Abnormal cardiac ... ORPHA:97297
Familial Aortic Dissection
Cardiomegaly ORPHA:229
Insensitivity To Pain, Congenital, With Anhidrosis
Self-mutilation, Osteomyelitis, Hyperactivity, Emotional lability OMIM:256800
Glycogen Storage Disease Of Heart, Lethal Congenital
Cardiomegaly, Cardiomyopathy, Biventricular hypertrophy OMIM:261740
Angelman Syndrome
Inability to walk, Inappropriate laughter, Aggressive behavior, Self-injurious behavior, Ataxia, ... ORPHA:72
Pitt-Hopkins-Like Syndrome 1
Aggressive behavior, Ataxia, Hyperactivity OMIM:610042
Koolen-De Vries Syndrome
Joint hypermobility, Atrial septal defect, Ventricular septal defect, Vertebral fusion, Pulmonic ... OMIM:610443
Pseudo-Torch Syndrome 3
Cardiomegaly OMIM:618886
Glycogen Storage Disease Due To Acid Maltase Deficiency
Osteoporosis, Inability to walk, Difficulty walking, Flexion contracture, Hepatomegaly, Cardiomeg... ORPHA:365
7Q11.23 Microduplication Syndrome
Joint hypermobility, Craniosynostosis, Atrial septal defect, Aggressive behavior, Ventricular sep... ORPHA:96121
Chromosome 13Q33-Q34 Deletion Syndrome
Aggressive behavior, Camptodactyly, Pulmonic stenosis, Left ventricular hypertrophy, Hyperactivity OMIM:619148
Fucosidosis
Hepatomegaly, Cardiomegaly ORPHA:349
Hennekam Lymphangiectasia-Lymphedema Syndrome 1
Atrial septal defect, Ventricular septal defect, Camptodactyly, Pericardial effusion, Joint contr... OMIM:235510
47,Xyy Syndrome
Impulsivity, Attention deficit hyperactivity disorder, Hyperactivity ORPHA:8
Angelman Syndrome
Progressive gait ataxia, Paroxysmal bursts of laughter, Broad-based gait, Hyperactivity OMIM:105830
Lethal Acantholytic Erosive Disorder
Cardiomegaly, Cardiomyopathy, Camptodactyly of toe ORPHA:158687
Citrullinemia Type Ii
Lethargy, Aggressive behavior, Hepatomegaly, Irritability, Hyperactivity ORPHA:247585
Brain-Lung-Thyroid Syndrome
Dystonia, Atrial septal defect, Ventricular septal defect, Ataxia, Falls, Hyperactivity, Patent f... ORPHA:209905
X-Linked Intellectual Disability, Cabezas Type
Camptodactyly of finger, Aggressive behavior, Joint hyperflexibility, Hyperactivity, Broad-based ... ORPHA:85293
21Q22.11Q22.12 Microdeletion Syndrome
Atrial septal defect, Inappropriate crying, Camptodactyly, Self-injurious behavior, Hyperactivity ORPHA:261323
Naxos Disease
Dilated cardiomyopathy, Abnormal morphology of right ventricular trabeculae, Right ventricular ca... OMIM:601214
White-Sutton Syndrome
Joint laxity, Aggressive behavior, Abnormal heart morphology, Self-injurious behavior, Hyperactivity ORPHA:468678
Maternal Phenylketonuria
Ventricular septal defect, Abnormal heart morphology, Double outlet right ventricle, Hypoplastic ... ORPHA:2209
X-Linked Cerebral Adrenoleukodystrophy
Inability to walk, Difficulty walking, Gait disturbance, Ataxia, Dysmetria, Hyperactivity, Hamstr... ORPHA:139396
Glycogen Storage Disease Ii
Hepatomegaly, Cardiomegaly, Splenomegaly OMIM:232300
Aicardi-Goutières Syndrome
Dystonia, Difficulty walking, Arthritis, Multiple joint contractures, Irritability, Cardiomegaly,... ORPHA:51
Sickle Cell Anemia
Hepatomegaly, Cardiomegaly, Splenomegaly OMIM:603903
Noonan Syndrome-Like Disorder With Loose Anagen Hair 1
Atrial septal defect, Joint laxity, Myelofibrosis, Ventricular septal defect, Pulmonic stenosis, ... OMIM:607721
Leigh Syndrome With Nephrotic Syndrome
Cardiomegaly ORPHA:255249
Glycogen Storage Disease Due To Acid Maltase Deficiency, Infantile Onset
Hepatomegaly, Left ventricular hypertrophy, Cardiomegaly, Hypertrophic cardiomyopathy ORPHA:308552
Carnitine Palmitoyl Transferase Ii Deficiency, Neonatal Form
Hepatomegaly, Abnormal myocardium morphology, Cardiomegaly, Cardiomyopathy ORPHA:228308
Williams Syndrome
Joint laxity, Abnormal endocardium morphology, Increased bone mineral density, Joint stiffness, C... ORPHA:904
Stankiewicz-Isidor Syndrome
Hyperactivity, Truncus arteriosus, Ventricular septal defect OMIM:617516
Argininemia
Hepatomegaly, Spastic gait, Irritability, Hyperactivity OMIM:207800
Bone Marrow Failure Syndrome 3
Reduced bone mineral density, Joint hypermobility, Hyperactivity OMIM:617052
Rubinstein-Taybi Syndrome Due To 16P13.3 Microdeletion
Atrial septal defect, Joint laxity, Aggressive behavior, Abnormal heart morphology, Ventricular s... ORPHA:353281
Truncus Arteriosus
Atrial septal defect, Truncus arteriosus, Abnormal heart morphology, Abnormal heart valve morphol... ORPHA:3384
Coffin-Siris Syndrome
Atrial septal defect, Joint laxity, Aggressive behavior, Ventricular septal defect, Abnormal hear... ORPHA:1465
Singleton-Merten Syndrome 1
Osteoporosis, Mitral valve calcification, Aortic valve stenosis, Waddling gait, Cardiomegaly, Aor... OMIM:182250
Histiocytoid Cardiomyopathy
Hepatomegaly, Lethargy, Cardiomegaly, Ventricular septal defect ORPHA:137675
Paternal Uniparental Disomy Of Chromosome 6
Hepatomegaly, Cardiomegaly, Joint laxity, Ventricular septal defect ORPHA:96191
Tuberous Sclerosis Complex
Cardiac rhabdomyoma, Aggressive behavior, Depression, Self-injurious behavior, Impulsivity, Anxie... ORPHA:805
Neurodegeneration With Brain Iron Accumulation 1
Dystonia, Akinesia, Depression, Gait disturbance, Blepharospasm, Ataxia, Bradykinesia, Hyperactivity OMIM:234200
Wiedemann-Steiner Syndrome
Aggressive behavior, Hyperextensibility at elbow, Low frustration tolerance, Anxiety, Hyperactivity ORPHA:319182
Dyrk1A-Related Intellectual Disability Syndrome
Ventricular septal defect, Gait disturbance, Aortic valve stenosis, Multiple joint contractures, ... ORPHA:464306
Distal Trisomy 17Q
Hyperactivity, Joint laxity, Abnormal heart morphology ORPHA:3379
Cerebellar Ataxia, Nonprogressive, With Mental Retardation
Aggressive behavior, Ataxia, Unsteady gait, Dysmetria, Hyperactivity OMIM:614756
Mend Syndrome
Hyperactivity, Aortic valve stenosis, Aggressive behavior, Abnormal heart morphology ORPHA:401973
Congenital Total Pulmonary Venous Return Anomaly
Cardiac total anomalous pulmonary venous connection, Atrial septal defect, Single ventricle, Vent... ORPHA:99125
Generalized Arterial Calcification Of Infancy
Ventricular hypertrophy, Hypophosphatemic rickets, Abnormal calcification of the carpal bones, Pe... ORPHA:51608
Familial Thoracic Aortic Aneurysm And Aortic Dissection
Cardiomegaly, Bicuspid aortic valve ORPHA:91387
Proteasome-Associated Autoinflammatory Syndrome 1
Camptodactyly of finger, Flexion contracture of finger, Flexion contracture of toe, Flexion contr... OMIM:256040
Rubinstein-Taybi Syndrome Due To Crebbp Mutations
Atrial septal defect, Joint laxity, Aggressive behavior, Abnormal heart morphology, Ventricular s... ORPHA:353277
Rubinstein-Taybi Syndrome Due To Ep300 Haploinsufficiency
Atrial septal defect, Joint laxity, Aggressive behavior, Abnormal heart morphology, Ventricular s... ORPHA:353284
Yunis-Varon Syndrome
Atrial septal defect, Ventricular septal defect, Cardiomegaly, Decreased skull ossification, Abse... ORPHA:3472
Early Infantile Epileptic Encephalopathy
Dystonia, Episodic ataxia, Ventricular septal defect, Self-injurious behavior, Hyperactivity ORPHA:1934
Spastic Tetraplegia-Thin Corpus Callosum-Progressive Postnatal Microcephaly Syndrome
Hair-pulling, Multiple joint contractures, Irritability, Hyperactivity ORPHA:447997
Hereditary Sensory And Autonomic Neuropathy Type 4
Self-mutilation, Abnormal emotion/affect behavior, Difficulty walking, Septic arthritis, Painless... ORPHA:642
Tropical Endomyocardial Fibrosis
Coronary artery stenosis, Restrictive cardiomyopathy, Myocardial calcification, Hepatomegaly, Lef... ORPHA:75565
Alpha-N-Acetylgalactosaminidase Deficiency Type 2
Cardiomegaly ORPHA:79280
Oculoectodermal Syndrome
Hyperactivity, Atrial septal defect, Hypertrophic cardiomyopathy OMIM:600268
Hyperthyroidism, Nonautoimmune
Hyperactivity OMIM:609152
Beckwith-Wiedemann Syndrome
Enlarged kidney, Hepatomegaly, Pancreatic hyperplasia, Cardiomegaly, Cardiomyopathy OMIM:130650
Beckwith-Wiedemann Syndrome
Enlarged kidney, Visceromegaly, Hepatomegaly, Cardiomegaly, Splenomegaly, Hypertrophic cardiomyop... ORPHA:116
Tetrasomy 9P
Pericarditis, Abnormal mitral valve morphology, Dextrocardia, Inappropriate behavior, Hyperactivi... ORPHA:3310
Histidinemia
Hyperactivity ORPHA:2157

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Negr1

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Negr1.

There are 2 publications which use IMPC produced mice or data.

Title Journal IMPC Allele PubMed ID
The new obesity-associated protein, neuronal growth regulator 1 (NEGR1), is implicated in Niemann-Pick disease Type C (NPC2)-mediated cholesterol trafficking. Biochemical and biophysical research communications (December 2016) Negr1tm1a(KOMP)Wtsi 27940359
Transcriptome Analysis of Targeted Mouse Mutations Reveals the Topography of Local Changes in Gene Expression. PLoS genetics (February 2016) Negr1tm1a(KOMP)Wtsi PMC4739719

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

This service may be affected by the Covid-19 pandemic. See how

MGI Allele Allele Type Produced
Negr1tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Negr1tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter