Gene: Arhgef10

Name
Rho guanine nucleotide exchange factor (GEF) 10
MGI ID
MGI:2444453
Synonyms
6430549H08Rik
View
N/A
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Significant
Not Significant
Not tested

Filtered by: all phenotypes

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Allele Center Procedure / Parameter Zygosity Mutants Statistical
Method
P Value Status
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forelimb digit - size HOM 8f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Tail - thickness HOM 8f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Arhgef10tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Alanine aminotransferase HOM 4f:5m Mixed Model framework, linear mixed-effects model, equation withWeight 0.160 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - hair distribution - back HOM 8f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Arhgef10tm1.1(KOMP)Vlcg JAX Eye Morphology / Bulging eye HOM 8f:8m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forelimb nail - shape HOM 8f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Arhgef10tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / RR HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.772 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin texture - whole body HOM 8f:9m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Trunk curl HOM 8f:9m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Eye Morphology / Iris/Pupil HOM 8f:8m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Plasma Chemistry / Triglycerides HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.217 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Eye Morphology / Corneal deposits HOM 8f:8m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Open Field / Percentage center time HOM 8f:9m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.837 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 6kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 6kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Body Composition (DEXA lean/fat) / Body length HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.302 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Vibrissae - presence HOM 8f:9m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Lower teeth appearance HOM 8f:9m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Eye Morphology / Lens Opacity HOM 8f:8m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin texture - back paws HOM 8f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forelimbs - shape HOM 8f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Arhgef10tm1.1(KOMP)Vlcg JAX Open Field / Periphery distance travelled HOM 8f:9m Mixed Model framework, linear mixed-effects model, equation withWeight 0.890 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Light-Dark Test / Dark side time spent HOM 8f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.814 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Sleep Wake / Sleep light phase percent HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.837 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Eye Morphology / Retina (combined) HOM 8f:8m Not processed Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Tail Suspension / Latency to immobility HOM 4f:3m Not processed 1.00 FAILED - Not enough data points in dependent variable 'JAX_TLS_002_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Arhgef10tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Calcium HOM 4f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0834 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Contact righting HOM 8f:9m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin color - ear HOM 8f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Grip Strength / Forelimb and hindlimb grip strength normalised against body weight HOM 8f:9m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0738 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindlimb nail - number HOM 8f:9m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - head HOM 8f:9m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0808 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - color - abdomen HOM 8f:9m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Rotarod / Learning slope HOM 6f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.540 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Eye Morphology / Pupil Dilation HOM 8f:8m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Potassium HOM 4f:5m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0582 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Body Composition (DEXA lean/fat) / Fat mass HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.190 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HOM 8f:4m Mixed Model framework, linear mixed-effects model, equation withWeight 0.414 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HOM 0f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.792 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 30kHz-evoked ABR Threshold HOM 2f:2m 0.216 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 30kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Phosphorus HOM 3f:5m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_CBC_010_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindpaw - shape HOM 8f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Tremor HOM 8f:9m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Viability Primary Screen / Outcome HOM 42f:45m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Genitalia - morphology HOM 8f:9m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Head morphology HOM 8f:9m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / ST HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.705 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Sleep Wake / Light sleep bout lengths mean HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.802 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Upper teeth appearance HOM 8f:9m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Open Field / Center distance travelled HOM 8f:9m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.800 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 18kHz-evoked ABR Threshold HOM 2f:2m 0.120 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 18kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Light-Dark Test / Percent time in dark HOM 8f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.703 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Eye Morphology / Corneal vascularization HOM 8f:8m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Eye Morphology / Retinal Blood Vessels Pattern HOM 8f:8m Fisher Exact Test framework 0.0667 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Triglycerides HOM 3f:5m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_CBC_017_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Arhgef10tm1.1(KOMP)Vlcg JAX Electroconvulsive Threshold Testing / mA threshold inducing clonic seizure HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.698 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Electroconvulsive Threshold Testing / mA threshold inducing clonic seizure HOM 0f:2m Not processed 1.00 FAILED - Not enough mutant or control data
Arhgef10tm1.1(KOMP)Vlcg JAX Sleep Wake / Light sleep bout lengths standard deviation HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.124 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / PQ HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.245 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Activity (body position) HOM 8f:9m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindlimb digit - size HOM 8f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin texture - snout HOM 8f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Arhgef10tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Total protein HOM 3f:5m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_CBC_006_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Arhgef10tm1.1(KOMP)Vlcg JAX Eye Morphology / Pupil Position HOM 8f:8m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Plasma Chemistry / HDL cholesterol HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0146 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Body Composition (DEXA lean/fat) / Fat/Body weight HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.132 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindlimbs - position HOM 8f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Arhgef10tm1.1(KOMP)Vlcg JAX Eye Morphology / Eyelid closure HOM 8f:8m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Light-Dark Test / Time mobile light side HOM 8f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.461 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forelimbs - size HOM 8f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Arhgef10tm1.1(KOMP)Vlcg JAX Sleep Wake / Breath rate during sleep standard deviation HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00531 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Tail - morphology HOM 8f:9m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - color pattern - abdomen HOM 8f:9m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Eye Morphology / Iris transilumination HOM 8f:8m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Aspartate aminotransferase HOM 4f:5m Mixed Model framework, linear mixed-effects model, equation withWeight 0.366 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindlimb nail - length HOM 8f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Vocalization HOM 8f:9m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Tail Suspension / Time immobile HOM 4f:3m Not processed 1.00 FAILED - Not enough data points in dependent variable 'JAX_TLS_001_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Arhgef10tm1.1(KOMP)Vlcg JAX Grip Strength / Forelimb and hindlimb grip strength measurement mean HOM 8f:9m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.148 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Open Field / Whole arena resting time HOM 8f:9m Mixed Model framework, linear mixed-effects model, equation withWeight 0.833 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Teeth presence HOM 8f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Arhgef10tm1.1(KOMP)Vlcg JAX Eye Morphology / Vitreous HOM 8f:8m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Eye Morphology / Lens HOM 8f:8m Fisher Exact Test framework 0.0339 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / QTc HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.693 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Grip Strength / Forelimb grip strength normalised against body weight HOM 8f:9m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0971 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Head size HOM 8f:9m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - color pattern - back HOM 8f:9m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Eye Morphology / Optic Disc HOM 8f:8m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Open Field / Center average speed HOM 8f:9m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.495 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Eye Morphology / Narrow eye opening HOM 8f:8m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Sodium HOM 4f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.239 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Sleep Wake / Sleep dark phase percent HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0529 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Heart Weight / Heart weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.181 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forepaw - shape HOM 8f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Arhgef10tm1.1(KOMP)Vlcg JAX Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull) HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.593 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin color - snout HOM 8f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Skin HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Skin HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Skin HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Skin HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - back HOM 8f:9m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Clinical Chemistry / HDL-cholesterol HOM 4f:5m Mixed Model framework, linear mixed-effects model, equation withWeight 0.462 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Eye Morphology / Persistence of hyaloid vascular system HOM 8f:8m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HOM 8f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.351 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HOM 0f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.654 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HOM 0f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0938 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HOM 8f:4m Mixed Model framework, linear mixed-effects model, equation withWeight 0.673 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Light-Dark Test / Latency to first transition into dark HOM 8f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.164 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Eye Morphology / Pupil Shape HOM 8f:8m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / QTc Dispersion HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.421 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Open Field / Periphery average speed HOM 8f:9m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.931 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Fertility of Homozygous Knock-out Mice / Gross Findings Male HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Eye Morphology / Eye HOM 8f:8m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Sleep Wake / Dark sleep bout lengths standard deviation HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.213 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Mouth morphology HOM 8f:9m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Head bobbing HOM 8f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Arhgef10tm1.1(KOMP)Vlcg JAX Light-Dark Test / Percent time in light HOM 8f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.703 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Plasma Chemistry / Total cholesterol HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0101 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Body Composition (DEXA lean/fat) / Lean/Body weight HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.700 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / rMSSD HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0737 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin texture - ear HOM 8f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Arhgef10tm1.1(KOMP)Vlcg JAX Open Field / Distance travelled - total HOM 8f:9m Mixed Model framework, linear mixed-effects model, equation withWeight 0.831 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Snout size HOM 8f:9m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / PR HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.237 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Sleep Wake / Dark sleep bout lengths mean HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.482 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Eye Morphology / Synechia HOM 8f:8m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Iron HOM 3f:5m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_CBC_011_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Arhgef10tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 24kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 24kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Total cholesterol HOM 4f:5m Mixed Model framework, linear mixed-effects model, equation withWeight 0.563 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Light-Dark Test / Light side time spent HOM 8f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.814 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Genitalia - size HOM 8f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Arhgef10tm1.1(KOMP)Vlcg JAX Open Field / Periphery permanence time HOM 8f:9m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.837 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Albumin HOM 4f:5m Mixed Model framework, linear mixed-effects model, equation withWeight 0.778 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forelimb nail - length HOM 8f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Arhgef10tm1.1(KOMP)Vlcg JAX Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.727 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / HR HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.764 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Aggression HOM 8f:9m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Grip Strength / Forelimb grip strength measurement mean HOM 8f:9m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0581 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindlimbs - shape HOM 8f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Startle response HOM 8f:9m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Urinary bladder HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Urinary bladder HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Urinary bladder HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Urinary bladder HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Eye Morphology / Eyelid morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - color - back HOM 8f:9m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Sleep Wake / Sleep daily percent HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.166 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forelimb digit - shape HOM 8f:9m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Free fatty acids HOM 3f:4m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_CBC_026_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Arhgef10tm1.1(KOMP)Vlcg JAX Eye Morphology / Cornea HOM 8f:8m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Open Field / Center permanence time HOM 8f:9m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.837 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 12kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 12kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindpaw - size HOM 8f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Arhgef10tm1.1(KOMP)Vlcg JAX Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull) HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.463 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Upper lip morphology HOM 8f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Locomotor activity HOM 8f:9m Mixed Model framework, linear mixed-effects model, equation withWeight 0.208 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Light-Dark Test / Fecal boli HOM 8f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.397 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin texture - tail HOM 8f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Vibrissae - appearance HOM 8f:9m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Eye Morphology / Iris Pigmentation HOM 8f:8m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Sleep Wake / Breath rate during sleep mean HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0775 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / HRV HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.956 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HOM 0f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.256 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HOM 8f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.717 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Eye Morphology / Retinal Blood Vessels HOM 8f:8m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Sleep Wake / Sleep bout lengths mean HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.221 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin color - back paws HOM 8f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Limb grasp HOM 8f:9m Fisher Exact Test framework 0.396 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin color - whole body HOM 8f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - hair distribution - abdomen HOM 8f:9m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Rotarod / Average duration HOM 6f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.184 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Plasma Chemistry / Glucose HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.000192 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Urea (Blood Urea Nitrogen - BUN) HOM 3f:4m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_CBC_004_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - color pattern - head HOM 8f:9m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Genitalia - presence HOM 8f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - hair distribution - head HOM 8f:9m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Light-Dark Test / Side changes HOM 8f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.438 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindlimb digit - number HOM 8f:9m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Eye Morphology / Corneal Sclerization HOM 8f:8m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Alkaline phosphatase HOM 4f:5m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0931 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Hole-board Exploration / Total holepokes HOM 8f:9m Mixed Model framework, linear mixed-effects model, equation withWeight 0.929 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Tail - length HOM 8f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Arhgef10tm1.1(KOMP)Vlcg JAX Eye Morphology / Eye Hemorrhage or Blood Presence HOM 8f:8m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindlimb nail - shape HOM 8f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Arhgef10tm1.1(KOMP)Vlcg JAX Open Field / Number of rears - total HOM 8f:9m Mixed Model framework, linear mixed-effects model, equation withWeight 0.312 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Unexpected behaviors HOM 8f:9m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global HOM 8f:4m Mixed Model framework, linear mixed-effects model, equation withWeight 0.330 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global HOM 0f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.819 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindlimbs - size HOM 8f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin texture - front paws HOM 8f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Arhgef10tm1.1(KOMP)Vlcg JAX Body Composition (DEXA lean/fat) / Bone Area HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.763 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Eye Morphology / Fusion between cornea and lens HOM 8f:8m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - color - head HOM 8f:9m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindlimb digit - shape HOM 8f:9m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00269 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Total bilirubin HOM 4f:5m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0723 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / CV HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.969 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forelimbs - position HOM 8f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forepaw - size HOM 8f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Arhgef10tm1.1(KOMP)Vlcg JAX Body Composition (DEXA lean/fat) / BMC/Body weight HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.341 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Lower lip morphology HOM 8f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin color - front paws HOM 8f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - abdomen HOM 8f:9m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Sleep Wake / Peak wake with respect to dark onset median HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.319 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Light-Dark Test / Time mobile dark side HOM 8f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.545 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Glucose HOM 3f:4m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_CBC_018_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Arhgef10tm1.1(KOMP)Vlcg JAX Eye Morphology / Retinal Blood Vessels Structure HOM 8f:8m Fisher Exact Test framework 0.0339 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Fertility of Homozygous Knock-out Mice / Gross Findings Female HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Tail Suspension / Climbing HOM 4f:3m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forelimb nail - number HOM 8f:9m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Gait HOM 8f:9m Fisher Exact Test framework 0.0168 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / QRS HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.728 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Ears HOM 8f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Tail - presence HOM 8f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Arhgef10tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Chloride HOM 4f:5m Mixed Model framework, linear mixed-effects model, equation withWeight 0.367 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Plasma Chemistry / Free fatty acids HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0111 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Rotarod / Learning difference HOM 6f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.679 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI4 HOM 8f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.327 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI4 HOM 0f:5m Mixed Model framework, generalized least squares, equation withoutWeight 0.963 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Body Composition (DEXA lean/fat) / Lean mass HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.886 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Eye Morphology / Pupil Light Response HOM 8f:8m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Open Field / Whole arena average speed HOM 8f:9m Mixed Model framework, linear mixed-effects model, equation withWeight 0.837 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Eye Morphology / Corneal opacity HOM 8f:8m Fisher Exact Test framework 1.00 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Sleep Wake / Sleep bout lengths standard deviation HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.739 Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forelimb digit - number HOM 8f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success
Arhgef10tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin color - tail HOM 8f:9m Fisher Exact Test framework 1.00 Not tested (No variation) - OK

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2) N/A
Aorta 2 No  (2/2) N/A
Brain 2 No  (2/2) N/A
Brainstem 2 No  (2/2) N/A
Brown adipose tissue 2 No  (2/2) N/A
Cartilage tissue 2 No  (2/2) N/A
Cerebellum 2 No  (2/2) N/A
Cerebral cortex 2 No  (2/2) N/A
Epididymis 2 No  (18/134)  (1/2) N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No  (2/2) N/A
Heart 2 No  (2/2) N/A
Hippocampus 2 No  (2/2) N/A
Hypothalamus 2 No  (2/2) N/A
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584)  (2/2) N/A
Liver 2 No  (2/2) N/A
Lower urinary tract 2 No N/A
Lung 2 No  (2/2) N/A
Lymph node 2 No  (2/2) N/A
Mammary gland 2 No  (1/2) N/A
Midbrain 2 No  (2/2) N/A
Olfactory lobe 2 No  (2/2) N/A
Ovary 2 No  (1/584)  (1/2) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/584)  (2/2) N/A
Peripheral nervous system 2 No  (2/2) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (2/2) N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (2/2) N/A
Small intestine 2 No  (9/584)  (2/2) N/A
Spinal cord 2 No  (2/2) N/A
Spleen 2 No  (2/584)  (2/2) N/A
Stomach 2 No  (12/584)  (2/2) N/A
Striatum 2 No  (2/2) N/A
Submandibular gland 2 No  (2/132)  (2/2) N/A
Testis 2 No  (2/584)  (1/2) N/A
Thalamus 2 No  (2/2) N/A
Thymus 2 No  (1/2) N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No  (2/2) N/A
Urinary bladder 2 No  (2/2) N/A
Uterus 2 No  (1/2) N/A
Vascular system 2 No  (2/2) N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No  (2/2) N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 1  (1/51)  (1/1) N/A
Brain 1  (6/485)  (1/2) N/A
Ear 1  (1/485) N/A
Embryo 1  (1/485)  (1/2)  Wholemount images
Eye 1  (1/485)  (1/2) N/A
Foot 1  (1/485)  (1/2) N/A
Forebrain 1  (1/485)  (1/2) N/A
Forelimb 1  (1/485)  (1/2) N/A
Hand 1  (1/485)  (1/2) N/A
Head 1  (5/485)  (1/2) N/A
Heart 1  (1/485)  (1/2) N/A
Hindbrain 1  (6/485)  (1/2) N/A
Hindlimb 1  (1/485)  (1/2) N/A
Liver 1  (1/485) N/A
Lung 1  (1/485) Image Only N/A
Mandibular process 1  (1/485)  (1/2) N/A
Maxillary process 1  (1/485)  (1/2) N/A
Midbrain 1  (1/485)  (1/2) N/A
Oral cavity 1  (1/485) N/A
Skeleton 1  (1/51)  (1/1) N/A
Skin 1  (1/485)  (1/2) N/A
Tail 1  (1/485)  (1/2) N/A
Tail somite 1  (1/485) N/A
Umbilical artery embryonic part 1  (1/47)  (1/1) N/A
Umbilical vein embryonic part 1  (1/47)  (1/1) N/A

 Associated Images

Sleep Wake: Wake state (bmp file)
13 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
X-ray: XRay Images Dorso Ventral
10 Images
X-ray: XRay Images Lateral Orientation
10 Images
X-ray: XRay Images Forepaw
10 Images
Embryo LacZ: LacZ images wholemount
16 Images
Combined SHIRPA and Dysmorphology
6 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Arhgef10tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Arhgef10tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice
Arhgef10tm94296(L1L2_Bact_P) Targeting vectors

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