Gene: Arhgef10

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Name
Rho guanine nucleotide exchange factor (GEF) 10
MGI ID
MGI:2444453
Synonyms
6430549H08Rik
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased circulating glucose level Arhgef10tm1.1(KOMP)Vlcg HOM Early adult 7.37×10-07
increased circulating potassium level Arhgef10tm1.1(KOMP)Vlcg HOM Early adult 6.38×10-06
increased circulating alanine transaminase level Arhgef10tm1.1(KOMP)Vlcg HOM Early adult 7.82×10-06

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
2 No  (4/584)  (2/2)  Section images
2 No  (1/584)  (2/2)  Section images
2 No  (4/584)  (2/2)  Section images
2 No  (2/584)  (2/2)  Section images
2 No  (2/2)  Section images
2 No  (1/584)  (2/2)  Section images
2 No  (3/584)  (2/2)  Section images
2 No  (2/584)  (2/2)  Section images
2 No  (17/133)  (1/2)  Section images
2 No  (7/408) N/A
2 No  (2/2)  Section images
2 No  (2/584)  (2/2)  Section images
2 No  (3/584)  (2/2)  Section images
2 No  (2/584)  (2/2)  Section images
2 No  (21/584)  (2/2)  Section images
2 No  (10/584)  (2/2)  Section images
2 No  (2/2)  Section images
2 No  (1/584) N/A
2 No  (2/584)  (2/2)  Section images
2 No  (1/584)  (2/2)  Section images
2 No  (1/2)  Section images
2 No  (2/2)  Section images
2 No  (2/584)  (2/2)  Section images
2 No  (1/584)  (1/2)  Section images
2 No  (1/2)  Section images
2 No  (5/584)  (2/2)  Section images
2 No  (2/584)  (2/2)  Section images
2 No N/A
2 No  (1/584)  (2/2)  Section images
2 No  (12/584) N/A
2 No  Section images
2 No  (1/584)  (2/2)  Section images
2 No  (9/584)  (2/2)  Section images
2 No  (3/584)  (2/2)  Section images
2 No  (3/584)  (2/2)  Section images
2 No  (12/584)  (2/2)  Section images
2 No  (3/584)  (2/2)  Section images
2 No  (2/131)  (2/2)  Section images
2 No  (6/584)  (1/2)  Section images
2 No  (2/2)  Section images
2 No  (1/584)  (1/2)  Section images
2 No  (16/584)  Section images
2 No  (3/584)  (2/2)  Section images
2 No  (2/2)  Section images
2 No  (1/2)  Section images
2 No  (2/2)  Section images
2 No N/A
2 No  (2/2)  Section images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 1  (1/63)  (1/1) N/A
Brain 1  (6/507)  (1/2) N/A
Ear 1  (1/507) N/A
Embryo 1  (1/508)  (1/2)  Wholemount images
Eye 1  (1/507)  (1/2) N/A
Footplate 1  (1/507)  (1/2) N/A
Forebrain 1  (1/507)  (1/2) N/A
Forelimb 1  (1/507)  (1/2) N/A
Handplate 1  (1/507)  (1/2) N/A
Head 1  (5/507)  (1/2) N/A
Heart 1  (1/507)  (1/2) N/A
Hindbrain 1  (6/507)  (1/2) N/A
Hindlimb 1  (1/507)  (1/2) N/A
Liver 1  (1/502) N/A
Lung 1  (1/502) Image Only N/A
Mandibular process 1  (1/507)  (1/2) N/A
Maxillary process 1  (1/507)  (1/2) N/A
Midbrain 1  (1/507)  (1/2) N/A
Oral cavity 1  (1/502) N/A
Skeleton 1  (1/77)  (1/1) N/A
Skin 1  (1/507)  (1/2) N/A
Tail 1  (1/507)  (1/2) N/A
Tail somite group 1  (1/507) N/A
Umbilical artery embryonic part 1  (1/59)  (1/1) N/A
Umbilical vein embryonic part 1  (1/59)  (1/1) N/A

 Associated Images

Sleep Wake: Wake state (bmp file)
13 Images
Embryo LacZ: LacZ images wholemount
16 Images
Original Image
Adult LacZ: LacZ Images Section
43 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
X-ray: XRay Images Forepaw
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
Combined SHIRPA and Dysmorphology
8 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
Eye Morphology: Images Ophthalmoscopy
1 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Arhgef10tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice
Arhgef10tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Arhgef10tm94296(L1L2_Bact_P) Targeting vectors

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