Genes Phenotypes

Gene: Hecw1

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Name
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
MGI ID
MGI:2444115
Synonyms
E130207I19Rik NEDL1
Viability
Homozygous - Viable
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (4) Measurements chart (246) All data table (588)
Expression & images (46) Disease models (0) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
impaired righting response Hecw1tm2b(EUCOMM)Hmgu HOM Middle aged adult 2.05×10-06
limb grasping Hecw1tm2b(EUCOMM)Hmgu HOM Early adult 1.69×10-07
tremors Hecw1tm2b(EUCOMM)Hmgu HOM Early adult 6.15×10-05
hypoactivity Hecw1tm2b(EUCOMM)Hmgu HOM Middle aged adult 4.86×10-05

Download data as:  TSV  XLS

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Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Bone 2 No N/A
Brain 2 No N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No N/A
Oral epithelium 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584)  (2/2)  Wholemount images
Striatum 2 No N/A
Testis 2 No  (2/584)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Uterus 2 No N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
digestive system (1)
Stomach expression
MA:0000353
postnatal mouse (2)
Stomach expression
MA:0000353
reproductive system (1)
Testis expression
MA:0000411
trunk (2)
Stomach expression
MA:0000353
LacZ Section Images
No Embryo expression data was found for this gene.

 Associated Images

Adult LacZ: LacZ Images Wholemount
2 Images
X-ray: XRay Images Whole Body Dorso Ventral
6 Images
X-ray: XRay Images Whole Body Lateral Orientation
6 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Hecw1tm2b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice
Hecw1tm2a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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