Genes Phenotypes

Gene: Sgms1

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Name
sphingomyelin synthase 1
MGI ID
MGI:2444110
Synonyms
SMS1beta SMS1gamma 9530058O11Rik SMS1alpha1 Tmem23 SMS1alpha2 SMS1
Viability
Homozygous - Viable
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (18) Measurements chart (319) All data table (838)
Expression & images (0) Disease models (0) Order (3)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
decreased circulating alanine transaminase level Sgms1tm1a(EUCOMM)Wtsi HOM Early adult 7.89×10-05
increased effector memory CD8-positive, alpha-beta T cell number Sgms1tm1a(EUCOMM)Wtsi HOM Early adult 8.01×10-24
increased grip strength Sgms1tm1a(EUCOMM)Wtsi HOM Early adult 4.70×10-07
thrombocytopenia Sgms1tm1a(EUCOMM)Wtsi HOM Early adult 6.18×10-09
decreased NK T cell number Sgms1tm1a(EUCOMM)Wtsi HOM Early adult 2.85×10-11
decreased total body fat amount Sgms1tm1a(EUCOMM)Wtsi HOM Early adult 1.65×10-09
decreased T cell number Sgms1tm1a(EUCOMM)Wtsi HOM Early adult 2.04×10-06
male infertility Sgms1tm1a(EUCOMM)Wtsi HOM Early adult 0.00
increased mean platelet volume Sgms1tm1a(EUCOMM)Wtsi HOM Early adult 2.93×10-14
decreased NK cell number Sgms1tm1a(EUCOMM)Wtsi HOM Early adult 4.05×10-07
tremors Sgms1tm1a(EUCOMM)Wtsi HOM Early adult 2.14×10-06
increased bone mineral content Sgms1tm1a(EUCOMM)Wtsi HOM Early adult 8.24×10-06
increased circulating alkaline phosphatase level Sgms1tm1a(EUCOMM)Wtsi HOM Early adult 1.24×10-07
increased circulating magnesium level Sgms1tm1a(EUCOMM)Wtsi HOM Early adult 3.53×10-06
increased lean body mass Sgms1tm1a(EUCOMM)Wtsi HOM Early adult 4.49×10-06
decreased mean corpuscular hemoglobin Sgms1tm1a(EUCOMM)Wtsi HOM Early adult 6.30×10-07
decreased CD8-positive, alpha-beta T cell number Sgms1tm1a(EUCOMM)Wtsi HOM Early adult 2.24×10-10
increased circulating amylase level Sgms1tm1a(EUCOMM)Wtsi HOM Early adult 8.95×10-06

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Viewing: all phenotypes

 Expression

Expression data not available

 Associated Images

DSS Histology
8 Images
X-ray: XRay Images Whole Body Lateral Orientation
28 Images
X-ray: XRay Images Whole Body Dorso Ventral
42 Images
X-ray: XRay Images Forepaw
14 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
14 Images
X-ray: XRay Images Skull Lateral Orientation
14 Images
Anti-nuclear antibody assay
6 Images
Legacy Phenotype Associated Images
Sgms1tm1a(EUCOMM)Wtsi
HOM, Female, WTSI
Sgms1tm1a(EUCOMM)Wtsi
HOM, Female, WTSI
Sgms1tm1a(EUCOMM)Wtsi
HOM, Female, WTSI
Sgms1tm1a(EUCOMM)Wtsi
HOM, Female, WTSI
Sgms1tm1a(EUCOMM)Wtsi
HOM, Male, WTSI

View all 111 images

Sgms1tm1a(EUCOMM)Wtsi
lateral ventricle, small lateral ventricles, HOM, Male, WTSI
Sgms1tm1a(EUCOMM)Wtsi
HOM, Male, WTSI
Sgms1tm1a(EUCOMM)Wtsi
HOM, Male, WTSI
Sgms1tm1a(EUCOMM)Wtsi
HOM, Male, WTSI
Sgms1tm1a(EUCOMM)Wtsi
lateral ventricle, small lateral ventricles, HOM, Male, WTSI

View all 15 images

Sgms1tm1a(EUCOMM)Wtsi
HOM, Male, WTSI

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Sgms1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Sgms1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Sgms1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells

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