Genes Phenotypes

Gene: Sgms1

Name
sphingomyelin synthase 1
MGI ID
MGI:2444110
Synonyms
Tmem23 9530058O11Rik SMS1gamma SMS1 SMS1beta SMS1alpha2 SMS1alpha1
Viability
Homozygous - Viable
View
N/A
Other links
MGI   Ensembl  
Significant phenotypes (18) Measurements chart (405) All data table (533)
Expression & images (0) Disease models (0) Order (3)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
increased circulating magnesium level Sgms1tm1a(EUCOMM)Wtsi HOM postnatal 3.89×10-06
thrombocytopenia Sgms1tm1a(EUCOMM)Wtsi HOM postnatal 6.38×10-09
increased lean body mass Sgms1tm1a(EUCOMM)Wtsi HOM postnatal 4.01×10-06
decreased total body fat amount Sgms1tm1a(EUCOMM)Wtsi HOM postnatal 1.58×10-09
decreased NK cell number Sgms1tm1a(EUCOMM)Wtsi HOM postnatal 4.22×10-07
increased circulating amylase level Sgms1tm1a(EUCOMM)Wtsi HOM postnatal 9.10×10-06
increased mean platelet volume Sgms1tm1a(EUCOMM)Wtsi HOM postnatal 4.30×10-14
decreased NK T cell number Sgms1tm1a(EUCOMM)Wtsi HOM postnatal 3.16×10-11
increased circulating alkaline phosphatase level Sgms1tm1a(EUCOMM)Wtsi HOM postnatal 1.29×10-07
male infertility Sgms1tm1a(EUCOMM)Wtsi HOM postpartum stage 0.00
decreased circulating alanine transaminase level Sgms1tm1a(EUCOMM)Wtsi HOM postnatal 6.97×10-05
increased grip strength Sgms1tm1a(EUCOMM)Wtsi HOM postnatal 5.06×10-07
decreased mean corpuscular hemoglobin Sgms1tm1a(EUCOMM)Wtsi HOM postnatal 8.20×10-07
decreased T cell number Sgms1tm1a(EUCOMM)Wtsi HOM postnatal 2.08×10-06
increased effector memory CD8-positive, alpha-beta T cell number Sgms1tm1a(EUCOMM)Wtsi HOM postnatal 5.82×10-24
decreased CD8-positive, alpha-beta T cell number Sgms1tm1a(EUCOMM)Wtsi HOM postnatal 2.32×10-10
tremors Sgms1tm1a(EUCOMM)Wtsi HOM postnatal 3.06×10-06
increased bone mineral content Sgms1tm1a(EUCOMM)Wtsi HOM postnatal 6.86×10-06

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Dorso Ventral
42 Images
X-ray: XRay Images Lateral Orientation
28 Images
X-ray: XRay Images Skull Lateral Orientation
14 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
14 Images
X-ray: XRay Images Forepaw
14 Images
Anti-nuclear antibody assay
6 Images
DSS Histology
8 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Sgms1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Sgms1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Sgms1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter