The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.
* Significant with a threshold of 1x10-3, check the Pain Sensitivity page for more information.
Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes
* Significant with a threshold of 1x10-3, check the Pain Sensitivity page for more information.
lacZ Expression
Expression data not available
Associated Images
Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.
Eye Morphology
Images Ophthalmoscopy
81 Images
X-ray
XRay Images Whole Body Lateral Orientation
10 Images
Gross Pathology and Tissue Collection
Images
8 Images
X-ray
XRay Images Skull Dorso Ventral Orientation
10 Images
X-ray
XRay Images Whole Body Dorso Ventral
10 Images
X-ray
XRay Images Skull Lateral Orientation
10 Images
Human diseases caused by Alg6 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.
There is no histopathology data for Alg6
IMPC related publications
The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Alg6.
No publications found that use IMPC mice or data for Alg6.
Order Mouse and ES Cells
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
MGI Allele
Allele Type
Produced
Alg6em1(IMPC)Tcp
Exon Deletion
Mice
Alg6tm1a(EUCOMM)Hmgu
KO first allele (reporter-tagged insertion with conditional potential)
Targeting vectors,ES Cells
Alg6tm1e(EUCOMM)Hmgu
Targeted, non-conditional allele
ES Cells
CRISPR Sequencing Data
Sequence
Guides
Sequence
Guide sequence
pam
chr
start
stop
strand
Genome build
gRNA Concentration
Truncated Guide
Reversed
Sanger service
Guide format
Guide source
Nucleases
Nuclease type
Nuclease class
Genotype primers
Sequence
Name
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