Gene: Ppfia2

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Name
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
MGI ID
MGI:2443834
Synonyms
E130120L08Rik Liprin-alpha2
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
head bobbing Ppfia2tm1b(EUCOMM)Hmgu HOM Early adult 3.60×10-07
abnormal retinal blood vessel morphology Ppfia2tm1b(EUCOMM)Hmgu HOM Early adult 2.99×10-05
abnormal optic disk morphology Ppfia2tm1b(EUCOMM)Hmgu HOM Early adult 4.11×10-05
increased prepulse inhibition Ppfia2tm1b(EUCOMM)Hmgu HOM Early adult 2.97×10-05
abnormal retinal vasculature morphology Ppfia2tm1b(EUCOMM)Hmgu HOM Early adult 7.99×10-05
abnormal gait Ppfia2tm1b(EUCOMM)Hmgu HOM Early adult 1.12×10-07

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (4/583)  (2/2)  Wholemount images
Aorta 2 No  (1/583) N/A
Bone 2 No N/A
Brain 2 No  (4/583)  (2/2)  Wholemount images
Brainstem 2 No  (2/583) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (1/583) N/A
Cerebellum 2 No  (3/583) N/A
Cerebral cortex 2 No  (2/583)  (2/2)  Wholemount images
Esophagus 2 No  (7/407) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (2/583) N/A
Hippocampus 2 No  (3/583)  (2/2)  Wholemount images
Hypothalamus 2 No  (2/583)  (2/2)  Wholemount images
Kidney 2 No  (21/583) N/A
Large intestine 2 No  (10/583) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/583) N/A
Lung 2 No  (2/583) N/A
Lymph node 2 No  (1/583)  (1/2)  Wholemount images
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/583)  (2/2)  Wholemount images
Oral epithelium 2 No N/A
Ovary 2 No  (1/583) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/583)  (1/2)  Wholemount images
Parathyroid gland 2 No  (1/563) N/A
Peripheral nervous system 2 No  (2/583) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/583)  (1/2)  Wholemount images
Prostate gland 2 No  (12/583) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (1/583) N/A
Small intestine 2 No  (9/583) N/A
Spinal cord 2 No  (3/583) N/A
Spleen 2 No  (3/583) N/A
Stomach 2 No  (13/583) N/A
Striatum 2 No  (3/583) N/A
Testis 2 No  (6/583)  (1/2)  Wholemount images
Thymus 2 No  (1/583) N/A
Thyroid gland 2 No  (17/583) N/A
Trachea 2 No  (3/583) N/A
Uterus 2 No N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
No Embryo expression data was found for this gene.

 Associated Images

X-ray: XRay Images Whole Body Dorso Ventral
9 Images
Echo: M-Mode Images
32 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
9 Images
X-ray: XRay Images Whole Body Lateral Orientation
9 Images
Adult LacZ: LacZ Images Wholemount
8 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
6 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Ppfia2tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Ppfia2tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice

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