Gene: Mat2a

Name
methionine adenosyltransferase II, alpha
MGI ID
MGI:2443731
Synonyms
D630045P18Rik
Viability
Homozygous - Lethal
Other links
View data by physiological system
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased prepulse inhibition Mat2atm1a(EUCOMM)Hmgu HET postnatal 1.05×10-11
increased startle reflex Mat2atm1a(EUCOMM)Hmgu HET postnatal 7.09×10-06
preweaning lethality, complete penetrance Mat2atm1b(EUCOMM)Hmgu HOM n/a 0.00
abnormal behavior Mat2atm1a(EUCOMM)Hmgu HET postnatal 4.76×10-05

Download data as:  TSV  XLS

Filtered by: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 4 No  (2/584)  Wholemount images
Aorta 4 No N/A
Bone 4 No  Wholemount images
Brain 4 No  (4/4)  Wholemount images
Brainstem 4 No N/A
Brown adipose tissue 4 No N/A
Cartilage tissue 4 No N/A
Cecum 4 No  (12/383)  (4/4)  Wholemount images
Cerebellum 4 No N/A
Cerebral cortex 4 No N/A
Chest bone 4 No  Wholemount images
Colon 4 No  (12/127)  (4/4) N/A
Cranium 4 No N/A
Diaphragm 4 No N/A
Duodenum 4 No  (2/127)  Wholemount images
Epididymis 4 No  (18/134)  Wholemount images
Esophagus 4 No  (7/415)  Wholemount images
Eye 4 No N/A
Gall bladder 4 No  Wholemount images
Gonadal fat pad 4 No N/A
Harderian gland 4 No  (4/4)  Wholemount images
Heart 4 No N/A
Hindlimb 4 No  Wholemount images
Hippocampus 4 No N/A
Hypothalamus 4 No N/A
Ileum 4 No  (14/127)  Wholemount images
Jejunum 4 No  (6/127)  Wholemount images
Kidney 4 No  (18/584)  (4/4)  Wholemount images
Large intestine 4 No  (10/584)  (4/4)  Wholemount images
Liver 4 No  Wholemount images
Lower urinary tract 4 No N/A
Lung 4 No N/A
Lymph node 4 No  Wholemount images
Main olfactory bulb 4 No N/A
Mammary gland 4 No N/A
Mesenteric adipose tissue 4 No  Wholemount images
Mesenteric lymph node 4 No  Wholemount images
Midbrain 4 No N/A
Olfactory lobe 4 No N/A
Oral epithelium 4 No N/A
Ovary 4 No  (1/584)  Wholemount images
Oviduct 4 No  Wholemount images
Pancreas 4 No  (5/584) N/A
Parathyroid gland 4 No N/A
Parotid gland 4 No  Wholemount images
Penis 4 No  (2/4)  Wholemount images
Peripheral nervous system 4 No  (4/4) N/A
Peyer's patch 4 No N/A
Pituitary gland 4 No  Wholemount images
Prostate gland 4 No  (12/584)  Wholemount images
Quadriceps 4 No N/A
Sciatic nerve 4 No  (4/4)  Wholemount images
Skeletal muscle 4 No N/A
Skin 4 No N/A
Small intestine 4 No  (9/584) N/A
Spinal cord 4 No  (4/4)  Wholemount images
Spleen 4 No  (2/584)  Wholemount images
Stomach 4 No  (12/584)  Wholemount images
Stomach pyloric region 4 No N/A
Striatum 4 No N/A
Sublingual gland 4 No  Wholemount images
Submandibular gland 4 No  (2/132)  Wholemount images
Testis 4 No  (2/584)  (2/4)  Wholemount images
Thalamus 4 No N/A
Thymus 4 No N/A
Thyroid gland 4 No  (15/584)  Wholemount images
Tongue 4 No  (5/127)  (4/4)  Wholemount images
Trachea 4 No N/A
Trigeminal V nerve 4 No  Wholemount images
Urinary bladder 4 No  Wholemount images
Uterus 4 No  Wholemount images
Vagina 4 No  Wholemount images
Vas deferens 4 No  (15/388) N/A
Vascular system 4 No N/A
Vesicular gland 4 No  Wholemount images
White adipose tissue 4 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 10  (6/485) N/A
Ear 10  (1/485) N/A
Embryo 10  (1/485)  Wholemount images
Eye 10  (1/485) N/A
Foot 10  (1/485) N/A
Forearm 10  (1/282) N/A
Forebrain 10  (1/485) N/A
Forelimb 10  (1/485) N/A
Hand 10  (1/485) N/A
Head 10  (5/485) N/A
Heart 10  (1/485) N/A
Hindbrain 10  (6/485) N/A
Hindlimb 10  (1/485) N/A
Liver 10  (1/485) N/A
Lower leg 10  (1/282) N/A
Lung 10  (1/485) N/A
Mandibular process 10  (1/485) N/A
Maxillary process 10  (1/485) N/A
Midbrain 10  (1/485) N/A
Oral cavity 10  (1/485) N/A
Skin 10  (1/485) N/A
Tail 10  (1/485) N/A
Tail somite 10  (1/485) N/A
Upper arm 10  (1/282) N/A
Upper leg 10  (1/282) N/A

 Associated Images

Eye Morphology: Images Ophthalmoscopy
5 Images
X-ray: XRay Images Dorso Ventral
10 Images
X-ray: XRay Images Lateral Orientation
10 Images
Adult LacZ: LacZ Images Wholemount
144 Images
Embryo LacZ: LacZ images wholemount
6 Images

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Mat2atm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice
Mat2atm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Mat2atm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells

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