Setx | senataxin
Physiological systems
20 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Vision/eye Hematopoietic system
14 No significant impact
4 Not tested
Data collections
Gene metrics:10Significant phenotypes
4Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
increased monocyte cell number | 1 supporting dataset | Setxtm1b(EUCOMM)Wtsi | homozygote | Early adult | 7.84x10-10 | ||
decreased lymphocyte cell number | 2 supporting datasets | Setxtm1b(EUCOMM)Wtsi | homozygote | Early adult | 6.23x10-6 | ||
male infertility | 1 supporting dataset | Setxtm1b(EUCOMM)Wtsi | homozygote | Early adult | N/A * | ||
decreased leukocyte cell number | 1 supporting dataset | Setxtm1b(EUCOMM)Wtsi | homozygote | Early adult | 9.29x10-5 | ||
increased neutrophil cell number | 1 supporting dataset | Setxtm1b(EUCOMM)Wtsi | homozygote | Early adult | 5.49x10-6 | ||
small testis | 1 supporting dataset | Setxtm1b(EUCOMM)Wtsi | homozygote | Early adult | N/A * | ||
increased NK cell number | 2 supporting datasets | Setxtm1b(EUCOMM)Wtsi | homozygote | Early adult | 2.36x10-5 | ||
improved glucose tolerance | 1 supporting dataset | Setxtm1b(EUCOMM)Wtsi | homozygote | Early adult | 1.85x10-5 | ||
increased eosinophil cell number | 1 supporting dataset | Setxtm1b(EUCOMM)Wtsi | homozygote | Early adult | 2.09x10-7 | ||
decreased total retina thickness | 1 supporting dataset | Setxtm1b(EUCOMM)Wtsi | homozygote | Early adult | 9.68x10-5 |
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External links
No external links available for Setx.
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Setxtm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
Setxtm1b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |