The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.
Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.
Legacy Phenotype Associated Images
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
The table below shows human diseases predicted to be associated to Kdm7a by phenotypic similarity.
The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Kdm7a.
There are 2 publications which use IMPC produced mice or data.
|Title||Journal||IMPC Allele||PubMed ID|
|Genome wide in vivo mouse screen data from studies to assess host regulation of metastatic colonisation.||Scientific data (September 2017)||Kdm7atm1a(EUCOMM)Wtsi||PMC5827107|
|Novel skin phenotypes revealed by a genome-wide mouse reverse genetic screen.||Nature communications (April 2014)||Kdm7atm1a(EUCOMM)Wtsi||PMC3996542|
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|MGI Allele||Allele Type||Produced|
|Kdm7atm1a(EUCOMM)Wtsi||KO first allele (reporter-tagged insertion with conditional potential)||Mice, Targeting vectors, ES Cells|