Not currently registered for phenotyping at IMPC
Phenotyping is currently not planned for a knockout strain of this gene.
Gene Summary
IMPC Data Collections
- No Body Weight Data
- No Embryo Imaging Data
- No Viability Data
Phenotyping is currently not planned for a knockout strain of this gene.
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
The table below shows human diseases predicted to be associated to Dhrs9 by phenotypic similarity.
Disease | Similarity of phenotypes |
Matching phenotypes | Source |
---|---|---|---|
Lactate Dehydrogenase B Deficiency | Reduced lactate dehydrogenase B level | OMIM:614128 | |
Deoxyribose-5-Phosphate Aldolase Deficiency | Abnormal circulating enzyme concentration or activity | OMIM:125460 | |
Hydroxyacyl Glutathione Hydrolase Deficiency | Glyoxalase deficiency | OMIM:614033 | |
Alcohol Sensitivity, Acute | Reduced acetaldehyde dehydrogenase level | OMIM:610251 | |
Acatalasemia | Reduced catalase level | OMIM:614097 | |
Platelet-Activating Factor Acetylhydrolase Deficiency | Platelet-activating factor acetylhydrolase deficiency | OMIM:614278 |
The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Dhrs9.
There are 1 publication which use IMPC produced mice or data.
Title | Journal | IMPC Allele | PubMed ID |
---|---|---|---|
Dehydrogenase reductase 9 (SDR9C4) and related homologs recognize a broad spectrum of lipid mediator oxylipins as substrates. | The Journal of biological chemistry (December 2021) | Dhrs9tm1(KOMP)Vlcg | PMC8761697 |
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
MGI Allele | Allele Type | Produced |
---|---|---|
Dhrs9tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | ES Cells |
Dhrs9tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | Targeting vectors, ES Cells |
Dhrs9tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | ES Cells |
Get highlights of the most important data releases, news and events, delivered straight to your email inbox
Subscribe to newsletter