Rc3h2 | ring finger and CCCH-type zinc finger domains 2

GeneMGI:2442789Synonyms: Mnab, 9430019J22Rik, +3 more

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Hematopoietic system Mortality/aging

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased circulating cholesterol level1 supporting datasetRc3h2tm1a(KOMP)WtsiheterozygoteEarly adult5.2x10-8 
increased circulating glycerol level1 supporting datasetRc3h2tm1a(KOMP)WtsiheterozygoteEarly adult1.67x10-5 
preweaning lethality, incomplete penetrance1 supporting datasetRc3h2tm1a(KOMP)WtsihomozygoteEarly adultN/A * 
increased circulating free fatty acids level1 supporting datasetRc3h2tm1a(KOMP)WtsiheterozygoteEarly adult5.05x10-6 
decreased T cell number1 supporting datasetRc3h2tm1a(KOMP)WtsiheterozygoteEarly adult5x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Rc3h2tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Rc3h2tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell
Rc3h2tm50154(L1L2_Pgk_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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