Name
Rho guanine nucleotide exchange factor (GEF) 4
MGI ID
MGI:2442507
Synonyms
9330140K16Rik
Asef
C230030N03Rik
Viability
N/A
Embryo viewer
N/A
Significant
Not Significant
Not tested
| Phenotype | System | Allele | Zyg | Sex | Life Stage | P Value |
|---|---|---|---|---|---|---|
| decreased IgE level | Arhgef4tm1a(KOMP)Wtsi | HOM | Early adult | 6.90×10-06 | ||
| decreased circulating serum albumin level | Arhgef4tm1a(KOMP)Wtsi | HOM | Early adult | 3.20×10-11 | ||
| increased mature B cell number | Arhgef4tm1a(KOMP)Wtsi | HOM | Early adult | 1.30×10-08 | ||
| abnormal behavior | Arhgef4tm1a(KOMP)Wtsi | HOM | Early adult | 3.59×10-08 | ||
| increased circulating creatinine level | Arhgef4tm1a(KOMP)Wtsi | HOM | Early adult | 5.15×10-07 | ||
| abnormal vibrissa morphology | Arhgef4tm1a(KOMP)Wtsi | HOM | Early adult | 7.77×10-06 | ||
| decreased circulating triglyceride level | Arhgef4tm1a(KOMP)Wtsi | HOM | Early adult | 5.39×10-12 | ||
| increased circulating free fatty acid level | Arhgef4tm1a(KOMP)Wtsi | HOM | Early adult | 4.17×10-07 | ||
| decreased circulating HDL cholesterol level | Arhgef4tm1a(KOMP)Wtsi | HOM | Early adult | 4.75×10-07 | ||
| decreased IgG1 level | Arhgef4tm1a(KOMP)Wtsi | HOM | Early adult | 7.13×10-07 | ||
| decreased T cell number | Arhgef4tm1a(KOMP)Wtsi | HOM | Early adult | 8.29×10-09 | ||
| decreased total body fat amount | Arhgef4tm1a(KOMP)Wtsi | HOM | Early adult | 1.27×10-08 | ||
| increased lean body mass | Arhgef4tm1a(KOMP)Wtsi | HOM | Early adult | 3.07×10-10 | ||
| decreased circulating LDL cholesterol level | Arhgef4tm1a(KOMP)Wtsi | HOM | Early adult | 1.51×10-06 | ||
| decreased circulating cholesterol level | Arhgef4tm1a(KOMP)Wtsi | HOM | Early adult | 4.83×10-12 | ||
| increased circulating total protein level | Arhgef4tm1a(KOMP)Wtsi | HOM | Early adult | 4.15×10-05 | ||
| hypoactivity | Arhgef4tm1a(KOMP)Wtsi | HOM | Early adult | 2.64×10-06 | ||
| increased startle reflex | Arhgef4tm1a(KOMP)Wtsi | HOM | Early adult | 5.86×10-06 | ||
| increased heart weight | Arhgef4tm1a(KOMP)Wtsi | HOM | Early adult | 4.48×10-05 | ||
| increased circulating glycerol level | Arhgef4tm1a(KOMP)Wtsi | HOM | Early adult | 9.35×10-07 | ||
| decreased mean corpuscular hemoglobin | Arhgef4tm1a(KOMP)Wtsi | HOM | Early adult | 3.23×10-06 | ||
| decreased hemoglobin content | Arhgef4tm1a(KOMP)Wtsi | HOM | Early adult | 3.10×10-05 | ||
| increased lactate dehydrogenase level | Arhgef4tm1a(KOMP)Wtsi | HOM | Early adult | 4.19×10-05 | ||
| increased bone mineral content | Arhgef4tm1a(KOMP)Wtsi | HOM | Early adult | 1.15×10-07 | ||
| increased circulating alkaline phosphatase level | Arhgef4tm1a(KOMP)Wtsi | HOM | Early adult | 9.92×10-07 | ||
| increased bone mineral density | Arhgef4tm1a(KOMP)Wtsi | HOM | Early adult | 1.94×10-08 | ||
| abnormal response to tactile stimuli | Arhgef4tm1a(KOMP)Wtsi | HOM | Early adult | 4.07×10-07 | ||
| decreased body weight | Arhgef4tm1a(KOMP)Wtsi | HOM | Early adult | 1.26×10-06 | ||
| decreased circulating alkaline phosphatase level | Arhgef4tm1a(KOMP)Wtsi | HOM | Early adult | 2.94×10-06 | ||
| decreased circulating free fatty acid level | Arhgef4tm1a(KOMP)Wtsi | HOM | Early adult | 2.65×10-05 | ||
| decreased bone mineral density | Arhgef4tm1a(KOMP)Wtsi | HOM | Early adult | 6.37×10-05 | ||
| decreased grip strength | Arhgef4tm1a(KOMP)Wtsi | HOM | Early adult | 9.63×10-05 |
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