Gene: Rhbdf2

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Name
rhomboid 5 homolog 2
MGI ID
MGI:2442473
Synonyms
4732465I17Rik Rhbdl6 iRhom2 cub
Viability
Embryo viewer
N/A
Other links
Expression & images (0) Disease models (0) Order (3)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased circulating triglyceride level Rhbdf2em1(IMPC)Wtsi HOM   Early adult 3.75×10-05
abnormal coat appearance Rhbdf2em1(IMPC)Wtsi HOM Early adult 2.23×10-17
decreased bone mineral density Rhbdf2Rhbdf2 HOM   Early adult 3.89×10-07
abnormal bone mineralization Rhbdf2tm1.1Mfm HOM Early adult 5.78×10-05
abnormal vibrissa morphology Rhbdf2em1(IMPC)Wtsi HOM   Early adult 1.60×10-07
alopecia Rhbdf2Rhbdf2 HOM Early adult 1.18×10-19
decreased circulating chloride level Rhbdf2em1(IMPC)Wtsi HOM   Early adult 4.59×10-10
decreased circulating HDL cholesterol level Rhbdf2Rhbdf2 HOM Early adult 5.31×10-05
decreased circulating creatinine level Rhbdf2Rhbdf2 HOM Early adult 8.49×10-15
decreased circulating alkaline phosphatase level Rhbdf2Rhbdf2 HOM Early adult 9.42×10-09
decreased circulating phosphate level Rhbdf2em1(IMPC)Wtsi HOM   Early adult 4.86×10-05
abnormal coat appearance Rhbdf2em1(IMPC)Wtsi HET Early adult 2.22×10-11
decreased circulating bilirubin level Rhbdf2em1(IMPC)Wtsi HOM   Early adult 5.29×10-06
decreased circulating cholesterol level Rhbdf2Rhbdf2 HOM   Early adult 3.34×10-07
trunk curl Rhbdf2Rhbdf2 HOM Early adult 3.10×10-05
increased circulating glucose level Rhbdf2Rhbdf2 HOM Early adult 2.44×10-05
decreased B cell number Rhbdf2Rhbdf2 HOM Early adult 3.01×10-05
increased B cell number Rhbdf2tm1.1Mfm HOM Early adult 3.82×10-05
increased lean body mass Rhbdf2em1(IMPC)Wtsi HOM Early adult 6.87×10-05
increased heart weight Rhbdf2Rhbdf2 HOM Early adult 3.25×10-06
increased total body fat amount Rhbdf2Rhbdf2 HOM Early adult 4.49×10-07
increased mean corpuscular hemoglobin Rhbdf2em1(IMPC)Wtsi HOM   Early adult 8.00×10-06
abnormal hair growth Rhbdf2em1(IMPC)Wtsi HOM Early adult 1.05×10-05
increased bone mineral content Rhbdf2tm1.1Mfm HOM Early adult 6.58×10-06
abnormal response to tactile stimuli Rhbdf2Rhbdf2 HOM Early adult 6.77×10-06
abnormal vibrissa morphology Rhbdf2em1(IMPC)Wtsi HET Early adult 6.82×10-06
abnormal response to new environment Rhbdf2Rhbdf2 HOM Early adult 7.12×10-05
tremors Rhbdf2Rhbdf2 HOM Early adult 6.92×10-06

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 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
X-ray: XRay Images Hind Leg and Hip
10 Images
X-ray: XRay Images Forepaw
10 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Rhbdf2tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Rhbdf2tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Rhbdf2em1(IMPC)Wtsi Point Mutation Mice

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