Rhbdf2 | rhomboid 5 homolog 2
Physiological systems
22 / 24 physiological systems tested
9 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Integument Adipose tissue Growth/size/body region Hematopoietic system Behavior/neurological Skeleton Cardiovascular system
13 No significant impact
2 Not tested
Data collections
Gene metrics:20Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
abnormal coat appearance | 5 supporting datasets | Rhbdf2em1(IMPC)Wtsi | heterozygote | Early adult | 2.22x10-11 | ||
abnormal vibrissa morphology | 3 supporting datasets | Rhbdf2em1(IMPC)Wtsi | homozygote | Early adult | 1.6x10-7 | ||
tremors | 1 supporting dataset | Rhbdf2Rhbdf2 | homozygote | Early adult | 6.92x10-6 | ||
abnormal response to tactile stimuli | 1 supporting dataset | Rhbdf2Rhbdf2 | homozygote | Early adult | 6.77x10-6 | ||
increased total body fat amount | 1 supporting dataset | Rhbdf2Rhbdf2 | homozygote | Early adult | 1.98x10-5 | ||
increased circulating magnesium level | 1 supporting dataset | Rhbdf2em1(IMPC)Wtsi | homozygote | Early adult | 9.33x10-5 | ||
alopecia | 1 supporting dataset | Rhbdf2Rhbdf2 | homozygote | Early adult | 1.18x10-19 | ||
decreased circulating alkaline phosphatase level | 1 supporting dataset | Rhbdf2Rhbdf2 | homozygote | Early adult | 9.42x10-9 | ||
increased heart weight | 1 supporting dataset | Rhbdf2Rhbdf2 | homozygote | Early adult | 3.25x10-6 | ||
abnormal coat appearance | 5 supporting datasets | Rhbdf2em1(IMPC)Wtsi | homozygote | Early adult | 2.23x10-17 |
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External links
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Rhbdf2em1(IMPC)Wtsi | Point Mutation | | mouse |
Rhbdf2tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
Rhbdf2tm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
Rhbdf2tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |