Gene: Efcab14

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Name
EF-hand calcium binding domain 14
MGI ID
MGI:2442397
Synonyms
4732418C07Rik
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased heart rate Efcab14tm1b(KOMP)Wtsi HOM Early adult 2.24×10-06
thin ventricular wall Efcab14tm1b(KOMP)Wtsi HOM Early adult 8.23×10-07
abnormal retinal outer nuclear layer morphology Efcab14tm1b(KOMP)Wtsi HOM   Early adult 1.06×10-05
abnormal retinal inner nuclear layer morphology Efcab14tm1b(KOMP)Wtsi HOM Early adult 6.28×10-09
increased bone mineral content Efcab14tm1b(KOMP)Wtsi HOM   Early adult 6.13×10-05
decreased cardiac muscle contractility Efcab14tm1b(KOMP)Wtsi HOM Early adult 6.46×10-06
decreased total retina thickness Efcab14tm1b(KOMP)Wtsi HOM Early adult 2.85×10-21

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Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (4/583)  (2/2)  Wholemount images
Aorta 2 No  (1/583)  (2/2)  Wholemount images
Bone 2 No  (2/2)  Wholemount images
Brain 2 No  (4/583)  (2/2)  Wholemount images
Brainstem 2 No  (2/583)  (2/2)  Wholemount images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (1/583)  (2/2)  Wholemount images
Cecum 1 No  (12/371) N/A
Cerebellum 2 No  (3/583)  (2/2)  Wholemount images
Cerebral cortex 2 No  (2/583)  (2/2)  Wholemount images
Esophagus 2 No  (7/407) N/A
Eye 2 No N/A
Gall bladder 2 No  (2/2)  Wholemount images
Heart 2 No  (2/583)  (2/2)  Wholemount images
Hippocampus 2 No  (3/583)  (2/2)  Wholemount images
Hypothalamus 2 No  (2/583)  (2/2)  Wholemount images
Kidney 2 No  (21/583)  (2/2)  Wholemount images
Large intestine 2 No  (10/583)  (2/2)  Wholemount images
Liver 2 No N/A
Lower urinary tract 2 No  (1/583)  (2/2)  Wholemount images
Lung 2 No  (2/583) N/A
Lymph node 2 No  (1/583) N/A
Mammary gland 2 No  (1/2)  Wholemount images
Mesenteric lymph node 2 No N/A
Olfactory lobe 2 No  (2/583)  (2/2)  Wholemount images
Oral epithelium 2 No N/A
Ovary 2 No  (1/583)  (1/2)  Wholemount images
Oviduct 2 No  (1/2)  Wholemount images
Pancreas 2 No  (5/583)  (2/2)  Wholemount images
Parathyroid gland 2 No  (1/563)  (2/2)  Wholemount images
Peripheral nervous system 2 No  (2/583)  (2/2)  Wholemount images
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/583) N/A
Prostate gland 2 No  (12/583)  (1/2)  Wholemount images
Skeletal muscle 2 No N/A
Skin 2 No  (1/583)  (2/2)  Wholemount images
Small intestine 2 No  (9/583) N/A
Spinal cord 2 No  (3/583)  (2/2)  Wholemount images
Spleen 2 No  (3/583) N/A
Stomach 2 No  (13/583) N/A
Striatum 2 No  (3/583)  (2/2)  Wholemount images
Testis 2 No  (6/583)  (1/2)  Wholemount images
Thymus 2 No  (1/583) N/A
Thyroid gland 2 No  (17/583)  (2/2)  Wholemount images
Trachea 2 No  (3/583)  (2/2)  Wholemount images
Trigeminal V nerve 2 No  (2/2)  Wholemount images
Urinary bladder 2 No  (2/2) N/A
Uterus 2 No  (1/2)  Wholemount images
Vas deferens 2 No  (15/382)  (1/2)  Wholemount images
Vascular system 2 No N/A
White adipose tissue 2 No N/A
No Embryo expression data was found for this gene.

 Associated Images

X-ray: XRay Images Skull Lateral Orientation
10 Images
Adult LacZ: LacZ Images Wholemount
17 Images
Eye Morphology: VIP of left fundus
19 Images
Eye Morphology: VIP of left eye
19 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
Eye Morphology: VIP of right fundus
19 Images
Eye Morphology: VIP of right eye
19 Images
X-ray: XRay Images Forepaw
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Efcab14tm36624(L1L2_Bact_P) Targeting vectors
Efcab14tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Efcab14tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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