Adap1 | ArfGAP with dual PH domains 1

GeneMGI:2442201Synonyms: Centa1, 4930431P11Rik, +1 more

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Immune system Hematopoietic system

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased NK cell number1 supporting datasetAdap1tm1a(EUCOMM)WtsihomozygoteEarly adultN/A * 
decreased memory-marker NK cell number1 supporting datasetAdap1tm1a(EUCOMM)WtsihomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Adap1tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Adap1tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Adap1tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell
Adap1tm2e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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