Gene Summary

Name:
CXXC finger 4
Synonyms:
Idax,  C030003J12Rik,  9330210J02Rik

IMPC Data Collections

IMPC Phenotype Summary

Significant
Not Significant
Not tested

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

Phenotype System Allele Zyg Sex Life Stage P Value
hyperactivity Cxxc4em1(IMPC)J HOM   Early adult 9.46×10-12
decreased bone mineral density Cxxc4em1(IMPC)J HOM Early adult 2.98×10-05
decreased bone mineral content Cxxc4em1(IMPC)J HOM Early adult 2.50×10-06
decreased thigmotaxis Cxxc4em1(IMPC)J HOM   Early adult 3.07×10-06

Download data as:  TSV  XLS

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lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

X-ray

XRay Images Whole Body Dorso Ventral

10 Images

X-ray

XRay Images Skull Dorso Ventral Orientation

10 Images

X-ray

XRay Images Whole Body Lateral Orientation

10 Images

X-ray

XRay Images Forepaw

10 Images

X-ray

XRay Images Skull Lateral Orientation

10 Images

Human diseases caused by Cxxc4 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Cxxc4 by phenotypic similarity.

Disease Similarity of
phenotypes
Matching phenotypes Source
Intellectual Developmental Disorder, X-Linked, Syndromic, Houge Type
Impulsivity, Attention deficit hyperactivity disorder, Hyperactivity OMIM:301008
Attention Deficit-Hyperactivity Disorder
Attention deficit hyperactivity disorder, Hyperactivity OMIM:143465
Intellectual Developmental Disorder, X-Linked 109
Impulsivity, Aggressive behavior, Hyperactivity OMIM:309548
Severe Primary Trimethylaminuria
Negative affectivity, Low self esteem, Aggressive behavior, Depression, Emotional lability, Anxiety ORPHA:468726
Autism, Susceptibility To, X-Linked 4
Impulsivity, Aggressive behavior, Attention deficit hyperactivity disorder OMIM:300830
Mental Retardation, Autosomal Dominant 45
Attention deficit hyperactivity disorder, Hyperactivity OMIM:617600
Familial Alzheimer-Like Prion Disease
Emotional lability, Anxiety, Attention deficit hyperactivity disorder, Depression ORPHA:280397
Mental Retardation, Autosomal Dominant 52
Anxiety, Hyperactivity OMIM:617796
Mental Retardation, Autosomal Recessive 54
Hyperactivity OMIM:617028
Schizophrenia 15
Hyperactivity OMIM:613950
Developmental And Epileptic Encephalopathy 56
Attention deficit hyperactivity disorder, Anxiety, Ataxia, Broad-based gait OMIM:617665
22q13 deletion syndrome (Phelan-Mcdermid syndrome)
Hyperactivity DECIPHER:20
Potocki-Lupski syndrome (17p11.2 duplication syndrome)
Hyperactivity DECIPHER:19
Mental Retardation, Autosomal Recessive 3
Hyperactivity OMIM:608443
Mental Retardation, Autosomal Recessive 66
Gait ataxia, Joint laxity, Attention deficit hyperactivity disorder, Aggressive behavior OMIM:618221
Mental Retardation, Autosomal Recessive 37
Aggressive behavior, Hyperactivity OMIM:615493
Immunodeficiency 8
Hyperactivity OMIM:615401
Spastic Tetraplegia, Thin Corpus Callosum, And Progressive Microcephaly
Inability to walk, Irritability, Hyperactivity OMIM:616657
Ank3-Related Intellectual Disability-Sleep Disturbance Syndrome
Aggressive behavior, Hyperactivity ORPHA:356996
Gilles De La Tourette Syndrome
Self-mutilation, Aggressive behavior, Attention deficit hyperactivity disorder OMIM:137580
Obsessive-Compulsive Disorder
Skin-picking, Anxiety, Depression OMIM:164230
Insulin-Like Growth Factor I Deficiency
Osteopenia, Hyperactivity OMIM:608747
Myoclonus-Dystonia Syndrome
Personality disorder, Dystonia, Depression, Writer's cramp, Panic attack, Torticollis, Anxiety ORPHA:36899
Epilepsy, Progressive Myoclonic, 12
Depression, Difficulty walking, Ataxia, Anxiety, Dysmetria, Attention deficit hyperactivity disorder OMIM:619191
Developmental And Epileptic Encephalopathy 43
Ataxia, Hyperactivity OMIM:617113
Smith-Magenis syndrome
Self-mutilation, Hyperactivity DECIPHER:8
Mental Retardation, Autosomal Dominant 33
Hyperactivity OMIM:616311
Glycine Encephalopathy
Lethargy, Aggressive behavior, Impulsivity, Irritability, Hyperactivity OMIM:605899
Pandas
Claustrophobia, Depression, Agoraphobia, Emotional lability, Separation insecurity, Impulsivity, ... ORPHA:66624
Intellectual Developmental Disorder, X-Linked 72
Hyperactivity OMIM:300271
Microcephaly 2, Primary, Autosomal Recessive, With Or Without Cortical Malformations
Impulsivity, Aggressive behavior, Hyperactivity OMIM:604317
Melorheostosis, Isolated
Hyperostosis, Increased bone mineral density OMIM:155950
Intellectual Disability-Expressive Aphasia-Facial Dysmorphism Syndrome
Hyperactivity ORPHA:436151
Juvenile Huntington Disease
Dystonia, Gait ataxia, Depression, Ataxia, Bradykinesia, Progressive cerebellar ataxia, Irritabil... ORPHA:248111
Phenylketonuria
Self-mutilation, Aggressive behavior, Depression, Irritability, Anxiety, Hyperactivity, Attention... OMIM:261600
Fraxe Intellectual Disability
Impulsivity, Aggressive behavior, Hyperactivity ORPHA:100973
Osteomalacia, Sclerosing, With Cerebral Calcification
Osteomalacia, Generalized osteosclerosis, Increased bone mineral density OMIM:259660
Mental Retardation, Autosomal Dominant 43
Impulsivity, Anxiety, Hyperactivity OMIM:616977
Hyperprolinemia, Type I
Aggressive behavior, Ataxia, Hyperactivity OMIM:239500
Sotos Syndrome 3
Hyperactivity OMIM:617169
Intellectual Developmental Disorder, X-Linked 101
Hyperactivity OMIM:300928
Microcephaly, Seizures, And Developmental Delay
Ataxia, Hyperactivity OMIM:613402
X-Linked Intellectual Disability-Psychosis-Macroorchidism Syndrome
Abnormal aggressive, impulsive or violent behavior, Bipolar affective disorder, Aggressive behavi... ORPHA:3077
Mannosidosis, Beta A, Lysosomal
Aggressive behavior, Hyperactivity OMIM:248510
Language Delay And Attention Deficit-Hyperactivity Disorder/Cognitive Impairment With Or Without Cardiac Arrhythmia
Attention deficit hyperactivity disorder, Hyperactivity OMIM:617182
Neurodevelopmental Disorder With Epilepsy And Hypoplasia Of The Corpus Callosum
Inability to walk, Gait disturbance, Dysmetria, Hyperactivity OMIM:618090
Dystonia 26, Myoclonic
Depression, Blepharospasm, Laryngeal dystonia, Torticollis, Anxiety OMIM:616398
Intellectual Developmental Disorder With Autistic Features And Language Delay, With Or Without Seizures
Joint hypermobility, Craniosynostosis, Spastic ataxia, Anxiety, Attention deficit hyperactivity d... OMIM:618906
Chromosome 3Q29 Deletion Syndrome
Anxiety, Gait ataxia, Aggressive behavior, Hyperactivity OMIM:609425
Intellectual Developmental Disorder, X-Linked 30
Anxiety, Aggressive behavior, Hyperactivity OMIM:300558
Intellectual Developmental Disorder, X-Linked 104
Aggressive behavior, Ataxia, Hyperactivity OMIM:300983
Lennox-Gastaut Syndrome
Personality disorder, Falls, Aggressive behavior, Hyperactivity ORPHA:2382
Coffin-Siris Syndrome 8
Self-injurious behavior, Aggressive behavior, Hyperactivity OMIM:618362
Xq25 Microduplication Syndrome
Anxiety, Hyperactivity ORPHA:521258
Xq25 Duplication Syndrome
Anxiety, Hyperactivity OMIM:300979
Ck Syndrome
Joint hypermobility, Aggressive behavior, Abnormal cortical bone morphology, Irritability, Hypera... OMIM:300831
Mental Retardation, Autosomal Recessive 39
Aggressive behavior, Hyperactivity OMIM:615541
Landau-Kleffner Syndrome
Gait ataxia, Aggressive behavior, Depression, Emotional lability, Impulsivity, Anxiety, Hyperacti... ORPHA:98818
Mental Retardation, X-Linked 77
Hyperactivity OMIM:300454
Hypophosphatemic Rickets, Autosomal Recessive, 1
Rickets, Hypophosphatemic rickets, Craniosynostosis, Increased bone mineral density OMIM:241520
Intellectual Developmental Disorder, X-Linked 107
Hyperactivity OMIM:301013
Aminoacylase 1 Deficiency
Hyperactivity OMIM:609924
Dystonia, Dopa-Responsive, Due To Sepiapterin Reductase Deficiency
Dystonia, Aggressive behavior, Ataxia, Hyperactivity OMIM:612716
Succinic Semialdehyde Dehydrogenase Deficiency
Aggressive behavior, Self-injurious behavior, Ataxia, Anxiety, Hyperactivity OMIM:271980
Encephalopathy, Progressive, With Or Without Lipodystrophy
Dystonia, Ataxia, Hyperactivity OMIM:615924
Angelman Syndrome Due To Imprinting Defect In 15Q11-Q13
Inappropriate laughter, Ataxia, Happy demeanor, Hyperactivity, Broad-based gait ORPHA:411515
X-Linked Intellectual Disability, Stocco Dos Santos Type
Hyperactivity ORPHA:85288
Early-Onset Schizophrenia
Low self esteem, Depression, Abnormal emotion/affect behavior, Impairment in personality function... ORPHA:96369
X-Linked Intellectual Disability-Hypotonia-Movement Disorder Syndrome
Aggressive behavior, Joint laxity, Broad-based gait, Hyperactivity ORPHA:457260
Guanidinoacetate Methyltransferase Deficiency
Dystonia, Aggressive behavior, Self-injurious behavior, Ataxia, Hyperactivity, Athetosis ORPHA:382
Hyperphosphatasia With Mental Retardation Syndrome 6
Aggressive behavior, Flexion contracture, Osteopenia, Knee flexion contracture, Hyperactivity, Hi... OMIM:616809
Ck Syndrome
Joint hypermobility, Irritability, Aggressive behavior, Hyperactivity ORPHA:251383
Autosomal Recessive Non-Syndromic Intellectual Disability
Dystonia, Impulsivity, Depression, Hyperactivity ORPHA:88616
Female Restricted Epilepsy With Intellectual Disability
Anxiety, Impulsivity, Aggressive behavior, Hyperactivity ORPHA:101039
Mental Retardation, Autosomal Recessive 38
Self-mutilation, Unsteady gait, Aggressive behavior, Hyperactivity OMIM:615516
Intellectual Developmental Disorder, X-Linked 21
Joint hypermobility, Impulsivity, Hyperactivity OMIM:300143
Neurodevelopmental Disorder With Behavioral Abnormalities, Absent Speech, And Hypotonia
Inability to walk, Paroxysmal bursts of laughter, Self-injurious behavior, Hyperactivity OMIM:618718
Intellectual Developmental Disorder With Abnormal Behavior, Microcephaly, And Short Stature
Aggressive behavior, Hyperactivity OMIM:618342
Clcn4-Related X-Linked Intellectual Disability Syndrome
Bipolar affective disorder, Aggressive behavior, Depression, Self-injurious behavior, Progressive... ORPHA:485350
Gand Syndrome
Inappropriate laughter, Hyperactivity OMIM:615074
8p23.1 deletion syndrome
Hyperactivity DECIPHER:39
Dihydropyrimidine Dehydrogenase Deficiency
Lethargy, Hyperactivity OMIM:274270
Cln5 Disease
Dysdiadochokinesis, Inability to walk, Truncal ataxia, Aggressive behavior, Ataxia, Unsteady gait... ORPHA:228360
Childhood-Onset Motor And Cognitive Regression Syndrome With Extrapyramidal Movement Disorder
Inability to walk, Dystonia, Gait ataxia, Aggressive behavior, Impulsivity, Hyperactivity ORPHA:500180
Mental Retardation, Autosomal Recessive 61
Aggressive behavior, Hyperactivity OMIM:617773
Clark-Baraitser Syndrome
Aggressive behavior, Hyperactivity OMIM:617752
Neurodevelopmental Disorder With Movement Abnormalities, Abnormal Gait, And Autistic Features
Unsteady gait, Happy demeanor, Broad-based gait, Hyperactivity OMIM:617865
Intellectual Developmental Disorder, X-Linked, Syndromic, Stocco Dos Santos Type
Hyperactivity OMIM:300434
Mucopolysaccharidosis, Type Iiib
Aggressive behavior, Joint stiffness, Dense calvaria, Hyperactivity OMIM:252920
Autism Spectrum Disorder Due To Auts2 Deficiency
Arthrogryposis multiplex congenita, Joint contracture of the 5th finger, Congenital contracture, ... ORPHA:352490
Mitochondrial Complex Iii Deficiency, Nuclear Type 7
Aggressive behavior, Hyperactivity OMIM:615824
Graves Disease, Susceptibility To, 1
Irritability, Hyperactivity OMIM:275000
X-Linked Creatine Transporter Deficiency
Self-mutilation, Dystonia, Joint hyperflexibility, Ataxia, Hyperactivity, Athetosis ORPHA:52503
Rasmussen Subacute Encephalitis
Inability to walk, Emotional lability, Irritability, Hemidystonia, Hyperactivity, Attention defic... ORPHA:1929
Symptomatic Form Of Fragile X Syndrome In Female Carrier
Aggressive behavior, Joint laxity, Depression, Self-injurious behavior, Irritability, Anxiety, Hy... ORPHA:449291
Gomez-Lopez-Hernandez Syndrome
Bipolar affective disorder, Craniosynostosis, Depression, Self-injurious behavior, Ataxia, Hypera... OMIM:601853
Optic Atrophy 11
Dysmetria, Ataxia, Hyperactivity OMIM:617302
Coffin-Siris Syndrome 7
Hyperactivity, Sagittal craniosynostosis OMIM:618027
Neurodevelopmental Disorder With Brain Abnormalities, Poor Growth, And Dysmorphic Facies
Aggressive behavior, Hyperactivity OMIM:615286
Infantile Neuroaxonal Dystrophy
Dystonia, Gait disturbance, Flexion contracture, Ataxia, Emotional lability, Unsteady gait, Impul... ORPHA:35069
X-Linked Intellectual Disability-Acromegaly-Hyperactivity Syndrome
Aggressive behavior, Hyperactivity ORPHA:85327
Mucopolysaccharidosis, Type Iiia
Joint stiffness, Dense calvaria, Hyperactivity OMIM:252900
Intellectual Developmental Disorder, X-Linked, Syndromic, Cabezas Type
Gait ataxia, Aggressive behavior, Joint laxity, Hyperactivity, Mood swings OMIM:300354
Hyperlysinemia, Type I
Hyperactivity OMIM:238700
X-Linked Adrenoleukodystrophy
Disinhibition, Aggressive behavior, Gait disturbance, Inappropriate sexual behavior, Hyperactivit... ORPHA:43
Hypomagnesemia, Seizures, And Mental Retardation 2
Self-biting, Hyperactivity OMIM:618314
Intellectual Developmental Disorder, X-Linked, Syndromic, Snijders Blok Type
Aggressive behavior, Broad-based gait, Hyperactivity OMIM:300958
Mental Retardation, Autosomal Dominant 7
Inappropriate laughter, Gait disturbance, Ataxia, Hyperactivity, Happy demeanor OMIM:614104
Adenylosuccinase Deficiency
Inability to walk, Self-mutilation, Gait ataxia, Inappropriate laughter, Aggressive behavior, Hyp... OMIM:103050
Severe Motor And Intellectual Disabilities-Sensorineural Deafness-Dystonia Syndrome
Aggressive behavior, Hyperactivity ORPHA:369939
Fragile X Syndrome
Joint laxity, Hyperactivity OMIM:300624
Inverted Duplicated Chromosome 15 Syndrome
Joint hypermobility, Self-biting, Aggressive behavior, Hyperactivity ORPHA:3306
2Q23.1 Microdeletion Syndrome
Paroxysmal bursts of laughter, Self-injurious behavior, Ataxia, Hyperactivity ORPHA:228402
Myoclonic-Astatic Epilepsy
Abnormal emotion/affect behavior, Ataxia, Unsteady gait, Hyperactivity, Attention deficit hyperac... ORPHA:1942
Neurodegeneration With Brain Iron Accumulation 2B
Dysdiadochokinesis, Dystonia, Gait ataxia, Bradykinesia, Emotional lability, Impulsivity, Dysmetr... OMIM:610217
19P13.3 Microduplication Syndrome
Osteoporosis, Self-injurious behavior, Irritability, Hyperactivity ORPHA:447980
Intellectual Developmental Disorder, Autosomal Recessive 71
Attention deficit hyperactivity disorder, Hyperactivity OMIM:618504
Severe Intellectual Disability-Short Stature-Behavioral Abnormalities-Facial Dysmorphism Syndrome
Irritability, Aggressive behavior, Hyperactivity ORPHA:391307
Mental Retardation, Autosomal Recessive 13
Hyperactivity OMIM:613192
Late Infantile Neuronal Ceroid Lipofuscinosis
Inability to walk, Aggressive behavior, Gait disturbance, Ataxia, Low frustration tolerance, Anxi... ORPHA:168491
Chromosome 2Q37 Deletion Syndrome
Self-injurious behavior, Aggressive behavior, Hyperactivity OMIM:600430
Growth Delay Due To Insulin-Like Growth Factor Type 1 Deficiency
Osteoporosis, Attention deficit hyperactivity disorder, Hyperactivity ORPHA:73272
Angelman Syndrome Due To Maternal 15Q11Q13 Deletion
Inappropriate laughter, Limitation of movement at ankles, Ataxia, Happy demeanor, Hyperactivity, ... ORPHA:98794
Intellectual Developmental Disorder, X-Linked, Syndromic, Lujan-Fryns Type
Joint laxity, Aggressive behavior, Flexion contracture, Emotional lability, Low frustration toler... OMIM:309520
Severe Neurodegenerative Syndrome With Lipodystrophy
Limb dystonia, Gait ataxia, Ataxia, Hyperactivity ORPHA:363400
Pitt-Hopkins-Like Syndrome 1
Aggressive behavior, Ataxia, Hyperactivity OMIM:610042
13Q12.3 Microdeletion Syndrome
Self-mutilation, Camptodactyly, Hyperactivity ORPHA:412035
Glass Syndrome
Aggressive behavior, Camptodactyly, Hyperactivity, Broad-based gait, Happy demeanor OMIM:612313
Developmental Delay With Variable Intellectual Impairment And Behavioral Abnormalities
Anxiety, Aggressive behavior, Ataxia, Hyperactivity OMIM:618430
Mucopolysaccharidosis, Type Iiic
Joint stiffness, Dense calvaria, Hyperactivity OMIM:252930
Insensitivity To Pain, Congenital, With Anhidrosis
Emotional lability, Self-mutilation, Osteomyelitis, Hyperactivity OMIM:256800
Chromosome 15Q25 Deletion Syndrome
Attention deficit hyperactivity disorder, Hyperactivity OMIM:614294
Cri-Du-Chat Syndrome
Self-mutilation, Aggressive behavior, Difficulty walking, Anxiety, Hyperactivity, Conspicuously h... OMIM:123450
Intellectual Disability, Birk-Barel Type
Contractures involving the joints of the feet, Limited elbow flexion/extension, Congenital finger... ORPHA:166108
Lamb-Shaffer Syndrome
Fused cervical vertebrae, Ataxia, Hyperactivity ORPHA:530983
Severe Intellectual Disability-Poor Language-Strabismus-Grimacing Face-Long Fingers Syndrome
Self-mutilation, Inappropriate laughter, Joint laxity, Low frustration tolerance, Hyperactivity ORPHA:363686
16P12.1P12.3 Triplication Syndrome
Skin-picking, Nail-biting, Anxiety, Hyperactivity, Attention deficit hyperactivity disorder ORPHA:485405
Chromosome 10Q26 Deletion Syndrome
Limited elbow extension, Craniosynostosis, Aggressive behavior, Hyperactivity, Broad-based gait OMIM:609625
Pediatric-Onset Graves Disease
Mood swings, Craniosynostosis, Irritability, Hyperactivity ORPHA:525731
Angelman Syndrome
Inability to walk, Inappropriate laughter, Aggressive behavior, Self-injurious behavior, Ataxia, ... ORPHA:72
47,Xyy Syndrome
Impulsivity, Attention deficit hyperactivity disorder, Hyperactivity ORPHA:8
19P13.12 Microdeletion Syndrome
Arthrogryposis multiplex congenita, Self-injurious behavior, Craniosynostosis, Hyperactivity ORPHA:254346
Intellectual Disability-Strabismus Syndrome
Aggressive behavior, Congenital finger flexion contractures, Gait disturbance, Achilles tendon co... ORPHA:363528
Angelman Syndrome
Progressive gait ataxia, Paroxysmal bursts of laughter, Broad-based gait, Hyperactivity OMIM:105830
Choreoacanthocytosis
Hair-pulling, Emotional lability, Head-banging, Progressive inability to walk, Falls, Hyperactivi... ORPHA:2388
X-Linked Cerebral Adrenoleukodystrophy
Inability to walk, Difficulty walking, Gait disturbance, Ataxia, Dysmetria, Hyperactivity, Hamstr... ORPHA:139396
X-Linked Intellectual Disability, Cabezas Type
Camptodactyly of finger, Aggressive behavior, Joint hyperflexibility, Hyperactivity, Broad-based ... ORPHA:85293
Neurodevelopmental Disorder With Or Without Autism Or Seizures
Hyperactivity OMIM:619239
Mucopolysaccharidosis, Type Iiid
Flexion contracture, Joint stiffness, Hyperactivity OMIM:252940
Histidinemia
Hyperactivity ORPHA:2157
Mucopolysaccharidosis Type 3
Disinhibition, Aggressive behavior, Craniofacial hyperostosis, Hypersexuality, Gait disturbance, ... ORPHA:581
Citrullinemia Type Ii
Lethargy, Irritability, Aggressive behavior, Hyperactivity ORPHA:247585
Bone Marrow Failure Syndrome 3
Joint hypermobility, Reduced bone mineral density, Hyperactivity OMIM:617052
Neurodegeneration With Brain Iron Accumulation 1
Dystonia, Akinesia, Depression, Gait disturbance, Blepharospasm, Ataxia, Bradykinesia, Hyperactivity OMIM:234200
7Q11.23 Microduplication Syndrome
Joint hypermobility, Craniosynostosis, Aggressive behavior, Self-injurious behavior, Unsteady gai... ORPHA:96121
Argininemia
Spastic gait, Irritability, Hyperactivity OMIM:207800
Hyperthyroidism, Nonautoimmune
Hyperactivity OMIM:609152
Neurodevelopmental Disorder With Coarse Facies And Mild Distal Skeletal Abnormalities
Joint hypermobility, Hyperactivity OMIM:618505
Cerebellar Ataxia, Nonprogressive, With Mental Retardation
Aggressive behavior, Ataxia, Unsteady gait, Dysmetria, Hyperactivity OMIM:614756
Spastic Paraplegia 29, Autosomal Dominant
Hyperactivity OMIM:609727
Wiedemann-Steiner Syndrome
Aggressive behavior, Low frustration tolerance, Hyperextensibility at elbow, Anxiety, Hyperactivity ORPHA:319182
Hyperlysinemia
Tip-toe gait, Craniosynostosis, Dysmetria, Hyperactivity ORPHA:2203
Purine Nucleoside Phosphorylase Deficiency
Ataxia, Hyperactivity ORPHA:760
Mucopolysaccharidosis Type 2
Aggressive behavior, Hip osteoarthritis, Flexion contracture of digit, Impulsivity, Hyperactivity... ORPHA:580
Spastic Tetraplegia-Thin Corpus Callosum-Progressive Postnatal Microcephaly Syndrome
Hair-pulling, Multiple joint contractures, Irritability, Hyperactivity ORPHA:447997
Tuberous Sclerosis Complex
Aggressive behavior, Depression, Self-injurious behavior, Impulsivity, Anxiety, Hyperactivity, At... ORPHA:805
Noonan Syndrome-Like Disorder With Loose Anagen Hair 1
Hyperactivity, Joint laxity, Attention deficit hyperactivity disorder, Myelofibrosis OMIM:607721
Hereditary Sensory And Autonomic Neuropathy Type 4
Self-mutilation, Difficulty walking, Abnormal emotion/affect behavior, Septic arthritis, Painless... ORPHA:642
Familial Gestational Hyperthyroidism
Hyperactivity ORPHA:99819
Rubinstein-Taybi Syndrome Due To 16P13.3 Microdeletion
Joint laxity, Aggressive behavior, Self-injurious behavior, Agoraphobia, Emotional lability, Pani... ORPHA:353281
Familial Hyperthyroidism Due To Mutations In Tsh Receptor
Hyperactivity ORPHA:424

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Cxxc4

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Cxxc4.

No publications found that use IMPC mice or data for Cxxc4.

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MGI Allele Allele Type Produced
Cxxc4em1(IMPC)J Intra-exon deletion Mice

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