Cxxc4 | CXXC finger 4
Physiological systems
17 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Behavior/neurological Skeleton
14 No significant impact
7 Not tested
Data collections
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| hyperactivity | 9 supporting datasets | Cxxc4em1(IMPC)J | homozygote | Early adult | 9.81x10-12 | ||
| decreased circulating creatinine level | 1 supporting dataset | Cxxc4em1(IMPC)J | homozygote | Early adult | 1.09x10-8 | ||
| decreased grip strength | 1 supporting dataset | Cxxc4em1(IMPC)J | homozygote | Early adult | 1.94x10-5 | ||
| decreased bone mineral content | 1 supporting dataset | Cxxc4em1(IMPC)J | homozygote | Early adult | 2.39x10-6 | ||
| decreased thigmotaxis | 2 supporting datasets | Cxxc4em1(IMPC)J | homozygote | Early adult | 8.33x10-6 |
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Human diseases caused by Cxxc4 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Cxxc4.
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| Cxxc4em1(IMPC)J | Intra-exon deletion | | mouse |