Genes Phenotypes

Gene: Arhgef11

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Name
Rho guanine nucleotide exchange factor (GEF) 11
MGI ID
MGI:2441869
Synonyms
PDZ-RhoGEF Prg
Viability
Homozygous - Viable
View
N/A
Other links
MGI   Ensembl  
Significant phenotypes (2) Measurements chart (218) All data table (221)
Expression & images (67) Disease models (0) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal retina morphology Arhgef11tm1b(KOMP)Wtsi HOM postnatal 2.19×10-10
increased aggression Arhgef11tm1b(KOMP)Wtsi HOM postnatal 5.30×10-05

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2)  Wholemount images
Aorta 2 No  (2/2)  Wholemount images
Bone 2 No  (2/2)  Wholemount images
Brain 2 No  (2/2)  Wholemount images
Brainstem 2 No  (2/2)  Wholemount images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No  Wholemount images
Cerebral cortex 2 No N/A
Esophagus 2 No  (7/415)  (2/2)  Wholemount images
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (2/2)  Wholemount images
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584)  (2/2)  Wholemount images
Large intestine 2 No  (10/584)  (2/2)  Wholemount images
Liver 2 No N/A
Lower urinary tract 2 No  (2/2)  Wholemount images
Lung 2 No N/A
Lymph node 2 No  (1/2)  Wholemount images
Mammary gland 2 No N/A
Olfactory lobe 2 No N/A
Oral epithelium 2 No N/A
Ovary 2 No  (1/584)  (1/2)  Wholemount images
Oviduct 2 No  (1/2)  Wholemount images
Pancreas 2 No  (5/584)  (2/2)  Wholemount images
Parathyroid gland 2 No  (2/2)  Wholemount images
Peripheral nervous system 2 No  (2/2)  Wholemount images
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (2/2)  Wholemount images
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No  (2/2)  Wholemount images
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584)  (2/2)  Wholemount images
Striatum 2 No N/A
Testis 2 No  (2/584)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Uterus 2 No  (1/2)  Wholemount images
Vascular system 2 No  (2/2)  Wholemount images
White adipose tissue 2 No N/A
LacZ Wholemount Images
cardiovascular system (2)
Aorta expression
Heart expression
MA:0000062
MA:0000072
digestive system (2)
Large Intestine expression
MA:0000333
endocrine system (2)
Adrenal gland expression
MA:0000116
immune system (1)
Lymph Node expression
MA:0000139
integumental system (1)
Skin expression
MA:0000151
musculoskeletal system (1)
Bone expression
MA:0001459
nervous system (5)
Cerebellum ambiguous
Brainstem expression
Brain expression
MA:0000198
MA:0000169
MA:0000168
postnatal mouse (19)
Adrenal gland expression
MA:0000116
reproductive system (2)
Ovary expression
Oviduct expression
Uterus expression
MA:0000384
MA:0000385
MA:0000389
trunk (9)
Adrenal gland expression
MA:0000116
urinary system (2)
Kidney expression
MA:0000368
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/485)  (4/4) N/A
Ear 2  (1/485)  (1/4) N/A
Embryo 2  (1/485)  (4/4) N/A
Eye 2  (1/485)  (4/4) N/A
Foot 2  (1/485) Image Only N/A
Forebrain 2  (1/485)  (3/4) N/A
Forelimb 2  (1/485)  (3/4) N/A
Hand 2  (1/485) Image Only N/A
Head 2  (5/485)  (4/4) N/A
Heart 2  (1/485)  (2/4) N/A
Hindbrain 2  (6/485)  (2/4) N/A
Hindlimb 2  (1/485)  (3/4) N/A
Liver 2  (1/485)  (1/4) N/A
Lung 2  (1/485)  (1/4) N/A
Mandibular process 2  (1/485)  (1/4) N/A
Maxillary process 2  (1/485)  (1/4) N/A
Midbrain 2  (1/485)  (3/4) N/A
Oral cavity 2  (1/485)  (1/4) N/A
Skin 2  (1/485)  (1/4) N/A
Tail 2  (1/485)  (4/4) N/A
Tail somite 2  (1/485)  (2/4) N/A

 Associated Images

Adult LacZ: LacZ Images Wholemount
19 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
X-ray: XRay Images Dorso Ventral
10 Images
X-ray: XRay Images Lateral Orientation
10 Images
Embryo LacZ: LacZ images wholemount
8 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Arhgef11tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Arhgef11tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice

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