Gene: Tlk1

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Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal response to new environment Tlk1tm1b(EUCOMM)Hmgu HOM Early adult 2.63×10-05

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Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (3/589)  (2/2)  Section images
Aorta 2 No  (1/589)  (2/2)  Section images
Brain 2 No  (3/589)  (2/2)  Section images
Brainstem 2 No  (2/589) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (2/2)  Section images
Cerebellum 2 No  (3/589)  (2/2)  Section images
Cerebral cortex 2 No  (2/589) N/A
Epididymis 2 No  (18/134)  (1/2)  Section images
Esophagus 2 No  (7/415)  (2/2)  Section images
Eye 2 No  (2/2)  Section images
Heart 2 No  (1/589)  (2/2)  Section images
Hippocampus 2 No  (3/589)  (1/2)  Section images
Hypothalamus 2 No  (2/589) N/A
Kidney 2 No  (20/589)  (2/2)  Section images
Large intestine 2 No  (10/589)  (2/2)  Section images
Liver 2 No N/A
Lower urinary tract 2 No  (1/589) N/A
Lung 2 No  (1/589)  (2/2)  Section images
Lymph node 2 No N/A
Mammary gland 2 No N/A
Midbrain 2 No N/A
Olfactory lobe 2 No  (2/589)  (2/2)  Section images
Ovary 2 No  (1/589)  (1/2)  Section images
Oviduct 2 No  (1/2)  Section images
Pancreas 2 No  (5/589)  (2/2)  Section images
Peripheral nervous system 2 No  (1/589)  (2/2)  Section images
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/589)  (2/2)  Section images
Prostate gland 2 No  (12/589) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (2/2)  Section images
Small intestine 2 No  (9/589)  (2/2)  Section images
Spinal cord 2 No  (2/589) N/A
Spleen 2 No  (2/589)  (2/2)  Section images
Stomach 2 No  (13/589)  (2/2)  Section images
Striatum 2 No  (3/589) N/A
Submandibular gland 2 No  (2/132)  (2/2)  Section images
Testis 2 No  (5/589)  (1/2)  Section images
Thalamus 2 No N/A
Thymus 2 No  (2/2)  Section images
Thyroid gland 2 No  (16/589) N/A
Trachea 2 No  (2/589)  (2/2)  Section images
Urinary bladder 2 No  (2/2)  Section images
Uterus 2 No  (1/2)  Section images
Vascular system 2 No  (2/2)  Section images
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/506)  (2/3) N/A
Dorsal root ganglion 2  (1/61)  (2/3) N/A
Ear 2  (1/506)  (2/3) N/A
Embryo 2  (1/507)  (2/3)  Wholemount images
Eye 2  (1/506)  (2/3) N/A
Foot 2  (1/506)  (2/3) N/A
Forebrain 2  (1/506)  (2/3) N/A
Forelimb 2  (1/506)  (2/3) N/A
Fronto-nasal process 2  (1/62) Image Only N/A
Hand 2  (1/505)  (2/3) N/A
Head 2  (5/506)  (2/3) N/A
Heart 2  (1/506)  (2/3) N/A
Hindbrain 2  (6/506)  (2/3) N/A
Hindlimb 2  (1/505)  (2/3) N/A
Liver 2  (1/506) Image Only N/A
Lung 2  (1/502) Image Only N/A
Mandibular process 2  (1/506)  (2/3) N/A
Maxillary process 2  (1/506)  (2/3) N/A
Midbrain 2  (1/506)  (2/3) N/A
Nose 2  (1/74)  (2/3) N/A
Oral cavity 2  (1/506) Image Only N/A
Skin 2  (1/506)  (2/3) N/A
Spinal cord 2  (1/73)  (2/3) N/A
Tail 2  (1/506)  (2/3) N/A
Tail somite 2  (1/506)  (2/3) N/A

 Associated Images

X-ray: XRay Images Whole Body Lateral Orientation
8 Images
X-ray: XRay Images Skull Lateral Orientation
8 Images
Embryo LacZ: LacZ images wholemount
12 Images
Adult LacZ: LacZ Images Section
30 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
8 Images
X-ray: XRay Images Forepaw
8 Images
X-ray: XRay Images Whole Body Dorso Ventral
8 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Tlk1tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice
Tlk1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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