Clrn1 | clarin 1

GeneMGI:2388124Synonyms: clarin-1, USH3, +2 more

Physiological systems

21 / 24 physiological systems tested

8 Significantly impacted by the knock-out

 Immune system Integument Hearing/vestibular/ear Liver/biliary system Respiratory system Hematopoietic system Behavior/neurological Renal/urinary system

13 No significant impact

3 Not tested

Gene metrics:8Significant phenotypes
4Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues

Phenotypes

abnormal auditory brainstem response6 supporting datasetsClrn1tm1.1(KOMP)VlcghomozygoteEarly adult2.22x10-6 
abnormal spleen morphology1 supporting datasetClrn1tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
abnormal kidney morphology1 supporting datasetClrn1tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
abnormal liver morphology1 supporting datasetClrn1tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
abnormal startle reflex1 supporting datasetClrn1tm1.1(KOMP)VlcghomozygoteEarly adult2.1x10-16 
abnormal lung morphology1 supporting datasetClrn1tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
abnormal skin morphology1 supporting datasetClrn1tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
abnormal vibrissa morphology1 supporting datasetClrn1tm1.1(KOMP)VlcghomozygoteEarly adult5.91x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* Does not have a P-value assigned because it was manually marked as significant.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Clrn1tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
mouse
Clrn1tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Clrn1tm115517(L1L2_Bact_P)Reporter-tagged deletion allele (with selection cassette)targeting vector
Clrn1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell

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