Gene: Ggnbp2

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Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased circulating total protein level Ggnbp2tm1b(KOMP)Wtsi HET postnatal 2.49×10-05
anophthalmia Ggnbp2tm1b(KOMP)Wtsi HOM embryonic day 15.5 0.00
abnormal embryo size Ggnbp2tm1b(KOMP)Wtsi HOM embryonic day 15.5 0.00
anophthalmia Ggnbp2tm1b(KOMP)Wtsi HET embryonic day 15.5 0.00
abnormal embryo size Ggnbp2tm1b(KOMP)Wtsi HET embryonic day 15.5 0.00
prenatal lethality prior to heart atrial septation Ggnbp2tm1b(KOMP)Wtsi HOM embryonic day 15.5 0.00
preweaning lethality, incomplete penetrance Ggnbp2tm1b(KOMP)Wtsi HOM n/a 0.00
abnormal behavior Ggnbp2tm1b(KOMP)Wtsi HET postnatal 2.78×10-09
edema Ggnbp2tm1b(KOMP)Wtsi HOM embryonic day 15.5 0.00
edema Ggnbp2tm1b(KOMP)Wtsi HET embryonic day 15.5 0.00

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Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

No Adult expression data was found for this gene.
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2  (1/51)  (2/2) N/A
Brain 3  (6/485)  (2/4) N/A
Central nervous system ganglion 2  (1/51)  (2/2) N/A
Ear 3  (1/485)  (2/4) N/A
Embryo 3  (1/485)  (2/4) N/A
Eye 3  (1/485)  (2/4) N/A
Foot 3  (1/485) N/A
Forebrain 3  (1/485)  (2/4) N/A
Forelimb 3  (1/485)  (2/4) N/A
Gut 2  (1/50)  (2/2) N/A
Hand 3  (1/485) N/A
Head 3  (5/485)  (2/4) N/A
Heart 3  (1/485)  (2/4) N/A
Hindbrain 3  (6/485)  (2/4) N/A
Hindlimb 3  (1/485)  (2/4) N/A
Liver 3  (1/485)  (2/4) N/A
Lung 3  (1/485)  (2/4) N/A
Mandibular process 3  (1/485)  (2/4) N/A
Maxillary process 3  (1/485)  (2/4) N/A
Midbrain 3  (1/485)  (2/4) N/A
Nose 2  (1/51)  (2/2) N/A
Oral cavity 3  (1/485)  (2/4) N/A
Skeleton 2  (1/51)  (2/2) N/A
Skin 3  (1/485)  (2/4) N/A
Spinal cord 2  (1/50)  (2/2) N/A
Tail 3  (1/485)  (2/4) N/A
Tail somite 3  (1/485)  (2/4) N/A
Trachea 2  (1/50)  (2/2) N/A
Urinary system 2  (1/50)  (2/2) N/A

 Associated Images

Gross Pathology and Tissue Collection
12 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
12 Images
X-ray: XRay Images Lateral Orientation
12 Images
Eye Morphology: Images Ophthalmoscopy
9 Images
Eye Morphology: Images Slit Lamp
2 Images
X-ray: XRay Images Dorso Ventral
12 Images
X-ray: XRay Images Skull Lateral Orientation
12 Images
Histopathology
8 Images
Gross Morphology Embryo E14.5-E15.5
6 Images
Combined SHIRPA and Dysmorphology
1 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Epididymis - depletion Ggnbp2tm1b(KOMP)Wtsi HOM postnatal
Testes - process of degenerative change Ggnbp2tm1b(KOMP)Wtsi HOM postnatal

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Ggnbp2tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Ggnbp2tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue

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