Gene: Ggnbp2

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Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased mean corpuscular hemoglobin Ggnbp2tm1b(KOMP)Wtsi HET   Early adult 9.62×10-05
hyperactivity Ggnbp2tm1b(KOMP)Wtsi HET Early adult 5.83×10-21
increased anxiety-related response Ggnbp2tm1b(KOMP)Wtsi HET Early adult 1.41×10-06
edema Ggnbp2tm1b(KOMP)Wtsi HOM E15.5 0.00
increased thigmotaxis Ggnbp2tm1b(KOMP)Wtsi HET Early adult 2.18×10-13
abnormal embryo size Ggnbp2tm1b(KOMP)Wtsi HOM E15.5 0.00
decreased circulating total protein level Ggnbp2tm1b(KOMP)Wtsi HET   Early adult 4.23×10-05
increased leukocyte cell number Ggnbp2tm1b(KOMP)Wtsi HET Early adult 6.63×10-05
edema Ggnbp2tm1b(KOMP)Wtsi HET E15.5 0.00
preweaning lethality, incomplete penetrance Ggnbp2tm1b(KOMP)Wtsi HOM   Early adult 0.00
anophthalmia Ggnbp2tm1b(KOMP)Wtsi HOM E15.5 0.00
abnormal behavior Ggnbp2tm1b(KOMP)Wtsi HET Early adult 2.20×10-13

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

No Adult expression data was found for this gene.
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
2  (1/64)  (2/2) N/A
3  (6/505)  (2/4) N/A
2  (1/73)  (2/2) N/A
3  (1/505)  (2/4) N/A
3  (1/506)  (2/4) N/A
3  (1/505)  (2/4) N/A
3  (1/505) N/A
3  (1/505)  (2/4) N/A
3  (1/505)  (2/4) N/A
2  (1/59)  (2/2) N/A
3  (1/505) N/A
3  (5/505)  (2/4) N/A
3  (1/505)  (2/4) N/A
3  (6/505)  (2/4) N/A
3  (1/505)  (2/4) N/A
3  (1/503)  (2/4) N/A
3  (1/503)  (2/4) N/A
3  (1/505)  (2/4) N/A
3  (1/505)  (2/4) N/A
3  (1/505)  (2/4) N/A
2  (1/75)  (2/2) N/A
3  (1/503)  (2/4) N/A
2  (1/75)  (2/2) N/A
3  (1/505)  (2/4) N/A
2  (1/72)  (2/2) N/A
3  (1/505)  (2/4) N/A
3  (1/505)  (2/4) N/A
2  (1/59)  (2/2) N/A
2  (1/59)  (2/2) N/A

 Associated Images

Gross Morphology Embryo E14.5-E15.5
6 Images
Eye Morphology: Images Ophthalmoscopy
9 Images
Gross Pathology and Tissue Collection
12 Images
X-ray: XRay Images Skull Lateral Orientation
12 Images
X-ray: XRay Images Whole Body Lateral Orientation
12 Images
X-ray: XRay Images Whole Body Dorso Ventral
12 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
12 Images
Embryo LacZ: LacZ images wholemount
16 Images
Histopathology
8 Images
Combined SHIRPA and Dysmorphology
1 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Testes - process of degenerative change Ggnbp2tm1b(KOMP)Wtsi HOM Early adult
Epididymis - depletion Ggnbp2tm1b(KOMP)Wtsi HOM Early adult

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Ggnbp2tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Ggnbp2tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue

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