Gene: Ggnbp2

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Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal embryo size Ggnbp2tm1b(KOMP)Wtsi HOM E15.5 0.00
decreased circulating total protein level Ggnbp2tm1b(KOMP)Wtsi HET Early adult 1.80×10-05
anophthalmia Ggnbp2tm1b(KOMP)Wtsi HOM E15.5 0.00
anophthalmia Ggnbp2tm1b(KOMP)Wtsi HET E15.5 0.00
preweaning lethality, incomplete penetrance Ggnbp2tm1b(KOMP)Wtsi HOM Early adult 0.00
edema Ggnbp2tm1b(KOMP)Wtsi HET E15.5 0.00
edema Ggnbp2tm1b(KOMP)Wtsi HOM E15.5 0.00
abnormal embryo size Ggnbp2tm1b(KOMP)Wtsi HET E15.5 0.00
prenatal lethality prior to heart atrial septation Ggnbp2tm1b(KOMP)Wtsi HOM E15.5 0.00
abnormal behavior Ggnbp2tm1b(KOMP)Wtsi HET Early adult 2.86×10-09

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Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

No Adult expression data was found for this gene.
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2  (1/61)  (2/2) N/A
Brain 3  (6/504)  (2/4) N/A
Central nervous system ganglion 2  (1/70)  (2/2) N/A
Ear 3  (1/504)  (2/4) N/A
Embryo 3  (1/505)  (2/4) N/A
Eye 3  (1/504)  (2/4) N/A
Foot 3  (1/504) N/A
Forebrain 3  (1/504)  (2/4) N/A
Forelimb 3  (1/504)  (2/4) N/A
Gut 2  (1/56)  (2/2) N/A
Hand 3  (1/503) N/A
Head 3  (5/504)  (2/4) N/A
Heart 3  (1/504)  (2/4) N/A
Hindbrain 3  (6/504)  (2/4) N/A
Hindlimb 3  (1/503)  (2/4) N/A
Liver 3  (1/504)  (2/4) N/A
Lung 3  (1/500)  (2/4) N/A
Mandibular process 3  (1/504)  (2/4) N/A
Maxillary process 3  (1/504)  (2/4) N/A
Midbrain 3  (1/504)  (2/4) N/A
Nose 2  (1/70)  (2/2) N/A
Oral cavity 3  (1/504)  (2/4) N/A
Skeleton 2  (1/70)  (2/2) N/A
Skin 3  (1/504)  (2/4) N/A
Spinal cord 2  (1/69)  (2/2) N/A
Tail 3  (1/504)  (2/4) N/A
Tail somite 3  (1/504)  (2/4) N/A
Trachea 2  (1/56)  (2/2) N/A
Urinary system 2  (1/56)  (2/2) N/A

 Associated Images

Histopathology
8 Images
X-ray: XRay Images Whole Body Dorso Ventral
12 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
12 Images
X-ray: XRay Images Whole Body Lateral Orientation
12 Images
Gross Pathology and Tissue Collection
12 Images
Embryo LacZ: LacZ images wholemount
16 Images
X-ray: XRay Images Skull Lateral Orientation
12 Images
Eye Morphology: Images Ophthalmoscopy
9 Images
Eye Morphology: Images Slit Lamp
2 Images
Gross Morphology Embryo E14.5-E15.5
6 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Testes - process of degenerative change Ggnbp2tm1b(KOMP)Wtsi HOM Early adult
Epididymis - depletion Ggnbp2tm1b(KOMP)Wtsi HOM Early adult

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Ggnbp2tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Ggnbp2tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue

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