Gene: Gtpbp10

Name
GTP-binding protein 10 (putative)
MGI ID
MGI:2385599
Synonyms
4930545J22Rik
Viability
Homozygous - Viable
Other links
Significant phenotypes (0) All measurements (102) Expression & images (73) Disease models (0) Order (2)
View data by physiological system
Significant
Not Significant
Not tested

Filtered by: all phenotypes

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Allele Center Procedure / Parameter Zygosity Mutants Statistical
Method
P Value Status
Gtpbp10tm1b(KOMP)Mbp JAX Eye Morphology / Bulging eye HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gtpbp10tm1b(KOMP)Mbp JAX Electrocardiogram (ECG) / RR HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.111 Success
Gtpbp10tm1b(KOMP)Mbp JAX Light-Dark Test / Percent time in light HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.766 Success
Gtpbp10tm1b(KOMP)Mbp JAX Eye Morphology / Iris/Pupil HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gtpbp10tm1b(KOMP)Mbp JAX Body Composition (DEXA lean/fat) / Lean/Body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00201 Success
Gtpbp10tm1b(KOMP)Mbp JAX Electrocardiogram (ECG) / rMSSD HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.249 Success
Gtpbp10tm1b(KOMP)Mbp JAX Open Field / Distance travelled - total HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0403 Success
Gtpbp10tm1b(KOMP)Mbp JAX Sleep Wake / Dark sleep bout lengths mean HOM 4f:4m Mixed Model framework, linear mixed-effects model, equation withWeight 0.185 Success
Gtpbp10tm1b(KOMP)Mbp JAX Electrocardiogram (ECG) / PR HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.458 Success
Gtpbp10tm1b(KOMP)Mbp JAX Eye Morphology / Synechia HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gtpbp10tm1b(KOMP)Mbp JAX Auditory Brain Stem Response / 24kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Gtpbp10tm1b(KOMP)Mbp JAX Auditory Brain Stem Response / 24kHz-evoked ABR Threshold HOM 0f:2m 1.00 Success
Gtpbp10tm1b(KOMP)Mbp JAX Light-Dark Test / Light side time spent HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.316 Success
Gtpbp10tm1b(KOMP)Mbp JAX Open Field / Periphery permanence time HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0593 Success
Gtpbp10tm1b(KOMP)Mbp JAX Eye Morphology / Corneal deposits HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gtpbp10tm1b(KOMP)Mbp JAX Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.000740 Success
Gtpbp10tm1b(KOMP)Mbp JAX Electrocardiogram (ECG) / HR HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.183 Success
Gtpbp10tm1b(KOMP)Mbp JAX Open Field / Percentage center time HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0592 Success
Gtpbp10tm1b(KOMP)Mbp JAX Auditory Brain Stem Response / 6kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Gtpbp10tm1b(KOMP)Mbp JAX Auditory Brain Stem Response / 6kHz-evoked ABR Threshold HOM 0f:2m 1.00 Success
Gtpbp10tm1b(KOMP)Mbp JAX Body Composition (DEXA lean/fat) / Body length HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.419 Success
Gtpbp10tm1b(KOMP)Mbp JAX Eye Morphology / Lens Opacity HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gtpbp10tm1b(KOMP)Mbp JAX Eye Morphology / Eyelid morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gtpbp10tm1b(KOMP)Mbp JAX Open Field / Periphery distance travelled HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.173 Success
Gtpbp10tm1b(KOMP)Mbp JAX Sleep Wake / Sleep daily percent HOM 4f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.198 Success
Gtpbp10tm1b(KOMP)Mbp JAX Light-Dark Test / Dark side time spent HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.316 Success
Gtpbp10tm1b(KOMP)Mbp JAX Sleep Wake / Sleep light phase percent HOM 4f:4m Mixed Model framework, linear mixed-effects model, equation withWeight 0.353 Success
Gtpbp10tm1b(KOMP)Mbp JAX Eye Morphology / Cornea HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gtpbp10tm1b(KOMP)Mbp JAX Eye Morphology / Retina (combined) HOM 8f:8m Not processed Success
Gtpbp10tm1b(KOMP)Mbp JAX Open Field / Center permanence time HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0592 Success
Gtpbp10tm1b(KOMP)Mbp JAX Auditory Brain Stem Response / 12kHz-evoked ABR Threshold HOM 0f:2m 1.00 Success
Gtpbp10tm1b(KOMP)Mbp JAX Auditory Brain Stem Response / 12kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Gtpbp10tm1b(KOMP)Mbp JAX Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull) HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.411 Success
Gtpbp10tm1b(KOMP)Mbp JAX Light-Dark Test / Fecal boli HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.617 Success
Gtpbp10tm1b(KOMP)Mbp JAX Eye Morphology / Iris Pigmentation HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gtpbp10tm1b(KOMP)Mbp JAX Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.373 Success
Gtpbp10tm1b(KOMP)Mbp JAX Electrocardiogram (ECG) / HRV HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0216 Success
Gtpbp10tm1b(KOMP)Mbp JAX Sleep Wake / Breath rate during sleep mean HOM 4f:4m Mixed Model framework, linear mixed-effects model, equation withWeight 0.314 Success
Gtpbp10tm1b(KOMP)Mbp JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HOM 8f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.0102 Success
Gtpbp10tm1b(KOMP)Mbp JAX Eye Morphology / Retinal Blood Vessels HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gtpbp10tm1b(KOMP)Mbp JAX Eye Morphology / Pupil Dilation HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gtpbp10tm1b(KOMP)Mbp JAX Body Composition (DEXA lean/fat) / Fat mass HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.000548 Success
Gtpbp10tm1b(KOMP)Mbp JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0865 Success
Gtpbp10tm1b(KOMP)Mbp JAX Auditory Brain Stem Response / 30kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Gtpbp10tm1b(KOMP)Mbp JAX Auditory Brain Stem Response / 30kHz-evoked ABR Threshold HOM 0f:2m 1.00 Success
Gtpbp10tm1b(KOMP)Mbp JAX Sleep Wake / Sleep bout lengths mean HOM 4f:4m Mixed Model framework, linear mixed-effects model, equation withWeight 0.921 Success
Gtpbp10tm1b(KOMP)Mbp JAX Viability Primary Screen / Outcome HOM 25f:26m Supplied as data Success
Gtpbp10tm1b(KOMP)Mbp JAX Sleep Wake / Light sleep bout lengths mean HOM 4f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.228 Success
Gtpbp10tm1b(KOMP)Mbp JAX Electrocardiogram (ECG) / ST HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.772 Success
Gtpbp10tm1b(KOMP)Mbp JAX Open Field / Center distance travelled HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0157 Success
Gtpbp10tm1b(KOMP)Mbp JAX Auditory Brain Stem Response / 18kHz-evoked ABR Threshold HOM 0f:2m 1.00 Success
Gtpbp10tm1b(KOMP)Mbp JAX Auditory Brain Stem Response / 18kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Gtpbp10tm1b(KOMP)Mbp JAX Light-Dark Test / Percent time in dark HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.766 Success
Gtpbp10tm1b(KOMP)Mbp JAX Eye Morphology / Corneal vascularization HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gtpbp10tm1b(KOMP)Mbp JAX Eye Morphology / Retinal Blood Vessels Pattern HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gtpbp10tm1b(KOMP)Mbp JAX Sleep Wake / Light sleep bout lengths standard deviation HOM 4f:4m Mixed Model framework, linear mixed-effects model, equation withWeight 0.588 Success
Gtpbp10tm1b(KOMP)Mbp JAX Electrocardiogram (ECG) / PQ HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.896 Success
Gtpbp10tm1b(KOMP)Mbp JAX Light-Dark Test / Side changes HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.628 Success
Gtpbp10tm1b(KOMP)Mbp JAX Eye Morphology / Corneal Sclerization HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gtpbp10tm1b(KOMP)Mbp JAX Eye Morphology / Eye Hemorrhage or Blood Presence HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gtpbp10tm1b(KOMP)Mbp JAX Open Field / Number of rears - total HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.464 Success
Gtpbp10tm1b(KOMP)Mbp JAX Eye Morphology / Pupil Position HOM 8f:8m Fisher Exact Test framework 0.333 Success
Gtpbp10tm1b(KOMP)Mbp JAX Body Composition (DEXA lean/fat) / Fat/Body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00154 Success
Gtpbp10tm1b(KOMP)Mbp JAX Body Composition (DEXA lean/fat) / Bone Area HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.444 Success
Gtpbp10tm1b(KOMP)Mbp JAX Eye Morphology / Eyelid closure HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gtpbp10tm1b(KOMP)Mbp JAX Eye Morphology / Fusion between cornea and lens HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gtpbp10tm1b(KOMP)Mbp JAX Light-Dark Test / Time mobile light side HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.708 Success
Gtpbp10tm1b(KOMP)Mbp JAX Sleep Wake / Breath rate during sleep standard deviation HOM 4f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0723 Success
Gtpbp10tm1b(KOMP)Mbp JAX Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0596 Success
Gtpbp10tm1b(KOMP)Mbp JAX Eye Morphology / Iris transilumination HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gtpbp10tm1b(KOMP)Mbp JAX Electrocardiogram (ECG) / CV HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0228 Success
Gtpbp10tm1b(KOMP)Mbp JAX Body Composition (DEXA lean/fat) / BMC/Body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00224 Success
Gtpbp10tm1b(KOMP)Mbp JAX Open Field / Whole arena resting time HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.124 Success
Gtpbp10tm1b(KOMP)Mbp JAX Eye Morphology / Vitreous HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gtpbp10tm1b(KOMP)Mbp JAX Eye Morphology / Lens HOM 8f:8m Fisher Exact Test framework 0.208 Success
Gtpbp10tm1b(KOMP)Mbp JAX Sleep Wake / Peak wake with respect to dark onset median HOM 4f:4m Mixed Model framework, linear mixed-effects model, equation withWeight 0.636 Success
Gtpbp10tm1b(KOMP)Mbp JAX Electrocardiogram (ECG) / QTc HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.319 Success
Gtpbp10tm1b(KOMP)Mbp JAX Eye Morphology / Optic Disc HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gtpbp10tm1b(KOMP)Mbp JAX Light-Dark Test / Time mobile dark side HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.00437 Success
Gtpbp10tm1b(KOMP)Mbp JAX Open Field / Center average speed HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.790 Success
Gtpbp10tm1b(KOMP)Mbp JAX Eye Morphology / Retinal Blood Vessels Structure HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gtpbp10tm1b(KOMP)Mbp JAX Eye Morphology / Narrow eye opening HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gtpbp10tm1b(KOMP)Mbp JAX Fertility of Homozygous Knock-out Mice / Gross Findings Female HOM f:m Supplied as data Success
Gtpbp10tm1b(KOMP)Mbp JAX Sleep Wake / Sleep dark phase percent HOM 4f:4m Mixed Model framework, linear mixed-effects model, equation withWeight 0.391 Success
Gtpbp10tm1b(KOMP)Mbp JAX Heart Weight / Heart weight HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.428 Success
Gtpbp10tm1b(KOMP)Mbp JAX Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull) HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.349 Success
Gtpbp10tm1b(KOMP)Mbp JAX Electrocardiogram (ECG) / QRS HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.333 Success
Gtpbp10tm1b(KOMP)Mbp JAX Eye Morphology / Persistence of hyaloid vascular system HOM 8f:8m Fisher Exact Test framework 0.102 Success
Gtpbp10tm1b(KOMP)Mbp JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0319 Success
Gtpbp10tm1b(KOMP)Mbp JAX Light-Dark Test / Latency to first transition into dark HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.186 Success
Gtpbp10tm1b(KOMP)Mbp JAX Eye Morphology / Pupil Shape HOM 8f:8m Fisher Exact Test framework 0.237 Success
Gtpbp10tm1b(KOMP)Mbp JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.914 Success
Gtpbp10tm1b(KOMP)Mbp JAX Open Field / Periphery average speed HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0560 Success
Gtpbp10tm1b(KOMP)Mbp JAX Electrocardiogram (ECG) / QTc Dispersion HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.153 Success
Gtpbp10tm1b(KOMP)Mbp JAX Fertility of Homozygous Knock-out Mice / Gross Findings Male HOM f:m Supplied as data Success
Gtpbp10tm1b(KOMP)Mbp JAX Eye Morphology / Eye HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gtpbp10tm1b(KOMP)Mbp JAX Body Composition (DEXA lean/fat) / Lean mass HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.836 Success
Gtpbp10tm1b(KOMP)Mbp JAX Sleep Wake / Dark sleep bout lengths standard deviation HOM 4f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.942 Success
Gtpbp10tm1b(KOMP)Mbp JAX Eye Morphology / Pupil Light Response HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gtpbp10tm1b(KOMP)Mbp JAX Open Field / Whole arena average speed HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0402 Success
Gtpbp10tm1b(KOMP)Mbp JAX Eye Morphology / Corneal opacity HOM 8f:8m Fisher Exact Test framework 0.138 Success
Gtpbp10tm1b(KOMP)Mbp JAX Sleep Wake / Sleep bout lengths standard deviation HOM 4f:4m Mixed Model framework, linear mixed-effects model, equation withWeight 0.691 Success

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No  (2/2) N/A
Brain 2 No N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Epididymis 2 No  (18/134)  (1/2) N/A
Esophagus 2 No  (7/415)  (2/2) N/A
Eye 2 No N/A
Heart 2 No  (2/2) N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584)  (2/2) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No  (2/2) N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Midbrain 2 No N/A
Olfactory lobe 2 No N/A
Ovary 2 No  (1/584)  (1/2) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/584) N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (2/2) N/A
Small intestine 2 No  (9/584)  (2/2) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584)  (2/2) N/A
Striatum 2 No N/A
Submandibular gland 2 No  (2/132) N/A
Testis 2 No  (2/584)  (1/2) N/A
Thalamus 2 No N/A
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Urinary bladder 2 No  (2/2) N/A
Uterus 2 No  (1/2) N/A
Vascular system 2 No  (2/2) N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/485) N/A
Dorsal root ganglion 2  (1/47) N/A
Ear 2  (1/485) N/A
Embryo 2  (1/485)  Wholemount images
Eye 2  (1/485) N/A
Foot 2  (1/485) N/A
Forebrain 2  (1/485) N/A
Forelimb 2  (1/485) N/A
Fronto-nasal process 2  (1/48) N/A
Hand 2  (1/485) N/A
Head 2  (5/485) N/A
Heart 2  (1/485) N/A
Hindbrain 2  (6/485) N/A
Hindlimb 2  (1/485) N/A
Liver 2  (1/485) N/A
Lung 2  (1/485) N/A
Mandibular process 2  (1/485) N/A
Maxillary process 2  (1/485) N/A
Midbrain 2  (1/485) N/A
Nose 2  (1/51) N/A
Oral cavity 2  (1/485) N/A
Skin 2  (1/485) N/A
Spinal cord 2  (1/50) N/A
Tail 2  (1/485) N/A
Tail somite 2  (1/485) N/A

 Associated Images

Embryo LacZ: LacZ images wholemount
4 Images
Sleep Wake: Wake state (bmp file)
6 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Gtpbp10tm1a(KOMP)Mbp KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Gtpbp10tm1b(KOMP)Mbp Reporter-tagged deletion allele (post-Cre) Mice

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