Gene: Tpcn2

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Name
two pore segment channel 2
MGI ID
MGI:2385297
Synonyms
D830047E22Rik
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal vocalization Tpcn2Gt(YHD437)Byg HOM Early adult 5.10×10-06
abnormal behavior Tpcn2Gt(YHD437)Byg HOM Early adult 1.36×10-05
decreased circulating sodium level Tpcn2Gt(YHD437)Byg HOM Early adult 3.81×10-09

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 8 No  (2/584)  (8/8) N/A
Aorta 8 No  (4/8) N/A
Bone 8 No  (8/8)  Wholemount images
Brain 8 No  (8/8) N/A
Brainstem 8 No  (8/8) N/A
Brown adipose tissue 8 No N/A
Cartilage tissue 8 No  (8/8)  Wholemount images
Cerebellum 8 No  (8/8) N/A
Cerebral cortex 8 No  (2/8) N/A
Esophagus 8 No  (7/415) N/A
Eye 8 No  (7/8)  Wholemount images
Gall bladder 8 No  (8/8)  Wholemount images
Heart 8 No  (4/8) N/A
Hippocampus 8 No  (8/8) N/A
Hypothalamus 8 No  (8/8) N/A
Kidney 8 No  (18/584)  (8/8)  Wholemount images
Large intestine 8 No  (10/584)  (8/8) N/A
Liver 8 No N/A
Lower urinary tract 8 No  (7/8) N/A
Lung 8 No  (7/8) N/A
Lymph node 8 No N/A
Mammary gland 8 No N/A
Olfactory lobe 8 No  (8/8) N/A
Oral epithelium 8 No  (6/8)  Wholemount images
Ovary 8 No  (1/584)  (4/8)  Wholemount images
Oviduct 8 No  (4/8)  Wholemount images
Pancreas 8 No  (5/584) N/A
Parathyroid gland 8 No  (7/8)  Wholemount images
Peripheral nervous system 8 No  (8/8)  Wholemount images
Peyer's patch 8 No N/A
Pituitary gland 8 No  (4/8) N/A
Prostate gland 8 No  (12/584)  (4/8) N/A
Skeletal muscle 8 No N/A
Skin 8 No  (7/8)  Wholemount images
Small intestine 8 No  (9/584)  (8/8) N/A
Spinal cord 8 No  (8/8)  Wholemount images
Spleen 8 No  (2/584)  (1/8) N/A
Stomach 8 No  (12/584)  (8/8)  Wholemount images
Striatum 8 No  (8/8) N/A
Testis 8 No  (2/584)  (4/8) N/A
Thymus 8 No  (7/8)  Wholemount images
Thyroid gland 8 No  (15/584)  (4/8) N/A
Trachea 8 No  (8/8)  Wholemount images
Uterus 8 No  (4/8)  Wholemount images
Vascular system 8 No  (8/8)  Wholemount images
White adipose tissue 8 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 4  (6/504)  (7/7) N/A
Ear 4  (1/504)  (1/7) N/A
Embryo 4  (1/505)  (7/7) N/A
Eye 4  (1/504)  (7/7) N/A
Foot 4  (1/504) Image Only N/A
Forebrain 4  (1/504)  (7/7) N/A
Forelimb 4  (1/504)  (7/7) N/A
Hand 4  (1/503) Image Only N/A
Head 4  (5/504)  (7/7) N/A
Heart 4  (1/504)  (2/7) N/A
Hindbrain 4  (6/504)  (7/7) N/A
Hindlimb 4  (1/503)  (7/7) N/A
Liver 4  (1/504)  (2/7) N/A
Lung 4  (1/500)  (2/7) N/A
Mandibular process 4  (1/504)  (1/7) N/A
Maxillary process 4  (1/504)  (1/7) N/A
Midbrain 4  (1/504)  (7/7) N/A
Oral cavity 4  (1/504)  (1/7) N/A
Skin 4  (1/504) N/A
Tail 4  (1/504)  (6/7) N/A
Tail somite 4  (1/504)  (3/7) N/A

 Associated Images

X-ray: XRay Images Whole Body Lateral Orientation
13 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
13 Images
X-ray: XRay Images Whole Body Dorso Ventral
13 Images
Echo: M-Mode Images
63 Images
Embryo LacZ: LacZ images wholemount
8 Images
Adult LacZ: LacZ Images Wholemount
12 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Tpcn2tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice
Tpcn2tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Tpcn2tm1c(EUCOMM)Hmgu Wild type floxed exon (post-Flp) Mice

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