Genes Phenotypes

Gene: Kctd15

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Name
potassium channel tetramerisation domain containing 15
MGI ID
MGI:2385276
Synonyms
MGC25497
Viability
Homozygous - Lethal
View
3D Imaging
Other links
MGI   Ensembl  
Significant phenotypes (7) Measurements chart (248) All data table (717)
Expression & images (41) Disease models (0) Order (4)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal embryo size Kctd15tm1b(EUCOMM)Wtsi HOM embryonic day 15.5 0.00
decreased food intake Kctd15tm1b(EUCOMM)Wtsi HET postnatal 1.97×10-05
prenatal lethality prior to heart atrial septation Kctd15tm1b(EUCOMM)Wtsi HOM embryonic day 15.5 0.00
abnormal behavior Kctd15tm1b(EUCOMM)Wtsi HET postnatal 3.85×10-05
decreased circulating alkaline phosphatase level Kctd15tm1b(EUCOMM)Wtsi HET postnatal 8.06×10-05
increased lymphocyte cell number Kctd15tm1b(EUCOMM)Wtsi HET postnatal 7.12×10-06
preweaning lethality, complete penetrance Kctd15tm1b(EUCOMM)Wtsi HOM n/a 0.00

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2)  Section images
Aorta 2 No N/A
Brain 2 No  (2/2)  Section images
Brainstem 2 No  (2/2)  Section images
Cartilage tissue 2 No  (2/2)  Section images
Cerebellum 2 No N/A
Cerebral cortex 2 No  (2/2) N/A
Esophagus 2 No  (7/415)  (2/2)  Section images
Eye 2 No  (1/2)  Section images
Heart 2 No N/A
Hippocampus 2 No  (2/2)  Section images
Hypothalamus 2 No  (2/2)  Section images
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584)  (1/2) N/A
Liver 2 No  (2/2)  Section images
Lower urinary tract 2 No  (2/2) N/A
Lung 2 No  (1/2)  Section images
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/2) N/A
Ovary 2 No  (1/584)  (1/2) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/584) N/A
Peripheral nervous system 2 No  (1/2)  Section images
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584)  (1/2) N/A
Skeletal muscle 2 No  (1/2)  Section images
Skin 2 No  (1/2)  Section images
Small intestine 2 No  (9/584)  (1/2) N/A
Spinal cord 2 No  (2/2)  Section images
Spleen 2 No  (2/584)  (1/2)  Section images
Stomach 2 No  (12/584)  (2/2) N/A
Striatum 2 No  (2/2)  Section images
Testis 2 No  (2/584)  (1/2) N/A
Thymus 2 No  (1/2)  Section images
Thyroid gland 2 No  (15/584)  (2/2) N/A
Trachea 2 No  (2/2)  Section images
Uterus 2 No  (1/2)  Section images
Vascular system 2 No N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
LacZ Section Images
digestive system (6)
Esophagus expression
MA:0000352
endocrine system (4)
Adrenal gland expression
MA:0000116
immune system (4)
Spleen expression
MA:0000141
integumental system (2)
Skin expression
MA:0000151
musculoskeletal system (2)
Skeletal Muscle expression
MA:0003148
nervous system (18)
Brain expression
MA:0000168
postnatal mouse (45)
Adrenal gland expression
MA:0000116
reproductive system (1)
Uterus expression
MA:0000389
respiratory system (3)
Lung expression
MA:0000415
sensory organ (3)
Eye expression
MA:0000261
set of connective tissues (2)
Cartilage tissue expression
MA:0000104
trunk (20)
Adrenal gland expression
MA:0000116
No Embryo expression data was found for this gene.

 Associated Images

Gross Pathology and Tissue Collection
8 Images
X-ray: XRay Images Lateral Orientation
42 Images
X-ray: XRay Images Hind Leg and Hip
16 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
16 Images
X-ray: XRay Images Dorso Ventral
26 Images
Eye Morphology: Images Ophthalmoscopy
20 Images
Eye Morphology: Images Slit Lamp
4 Images
Adult LacZ: LacZ Images Section
45 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Kctd15tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Kctd15tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Kctd15tm47323(L1L2_gt0) Targeting vectors
Kctd15tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue

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