Gene: Gys2

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Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased erythrocyte cell number Gys2tm1a(KOMP)Wtsi HOM Early adult 9.77×10-06
abnormal vibrissa morphology Gys2tm1a(KOMP)Wtsi HOM Early adult 4.19×10-05
abnormal coat/ hair morphology Gys2tm1a(KOMP)Wtsi HOM   Early adult 8.08×10-07
increased circulating calcium level Gys2tm1a(KOMP)Wtsi HOM Early adult 2.23×10-06
increased total body fat amount Gys2tm1a(KOMP)Wtsi HOM Early adult 4.36×10-06
increased circulating total protein level Gys2tm1a(KOMP)Wtsi HOM Early adult 2.72×10-06
decreased circulating glycerol level Gys2tm1a(KOMP)Wtsi HOM Early adult 3.36×10-06
decreased body weight Gys2tm1a(KOMP)Wtsi HOM Early adult 1.20×10-15
increased circulating sodium level Gys2tm1a(KOMP)Wtsi HOM   Early adult 1.20×10-11
decreased circulating glucose level Gys2tm1a(KOMP)Wtsi HOM Early adult 2.55×10-26
increased circulating chloride level Gys2tm1a(KOMP)Wtsi HOM Early adult 2.35×10-06
increased bone mineral density Gys2tm1a(KOMP)Wtsi HOM Early adult 3.67×10-05
increased lean body mass Gys2tm1a(KOMP)Wtsi HOM Early adult 1.27×10-05

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 5 No  (4/583) N/A
Aorta 5 No  (1/583) N/A
Blood vessel 5 No N/A
Bone 5 No N/A
Brain 5 No  (4/583) N/A
Brainstem 5 No  (2/583) N/A
Brown adipose tissue 5 No N/A
Cartilage tissue 5 No  (1/583) N/A
Cerebellum 5 No  (3/583) N/A
Cerebral cortex 5 No  (2/583) N/A
Eye 5 No N/A
Gall bladder 5 No N/A
Heart 5 No  (2/583) N/A
Hippocampus 5 No  (3/583) N/A
Hypothalamus 5 No  (2/583) N/A
Kidney 5 No  (21/583) N/A
Large intestine 5 No  (10/583) N/A
Liver 5 No N/A
Lower urinary tract 5 No  (1/583) N/A
Lung 5 No  (2/583) N/A
Lymph node 5 No  (1/583) N/A
Mammary gland 5 No N/A
Esophagus 5 No N/A
Olfactory lobe 5 No  (2/583) N/A
Ovary 5 No  (1/583) N/A
Oviduct 5 No N/A
Pancreas 5 No  (5/583)  (1/5) N/A
Parathyroid gland 5 No  (1/563) N/A
Peripheral nervous system 5 No  (2/583) N/A
Peyer's patch 5 No  (1/176) N/A
Pituitary gland 5 No  (1/583) N/A
Prostate gland 5 No  (12/583) N/A
Skeletal muscle tissue 5 No N/A
Skin 5 No  (1/583) N/A
Small intestine 5 No  (9/583) N/A
Spinal cord 5 No  (3/583) N/A
Spleen 5 No  (3/583) N/A
Stomach 5 No  (13/583) N/A
Striatum 5 No  (3/583) N/A
Testis 5 No  (6/583)  (2/5) N/A
Thymus 5 No  (1/583) N/A
Thyroid gland 5 No  (17/583) N/A
Trachea 5 No  (3/583) N/A
Uterus 5 No  (1/5) N/A
White adipose tissue 5 No N/A
LacZ Section Images
No Embryo expression data was found for this gene.

 Associated Images

Histopathology
14 Images
Legacy Phenotype Associated Images

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 Disease Models

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 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Spleen - hyperplasia Gys2tm1a(KOMP)Wtsi HOM Early adult
Spleen - MPATH diagnostic term extramedullary hemopoiesis Gys2tm1a(KOMP)Wtsi HOM Early adult
Liver - lipid deposition Gys2tm1a(KOMP)Wtsi HOM Early adult
Liver - iron deposition Gys2tm1a(KOMP)Wtsi HOM Early adult
Liver - process of degenerative change Gys2tm1a(KOMP)Wtsi HOM Early adult

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Gys2tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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