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Gene: Gys2

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Name
glycogen synthase 2
MGI ID
MGI:2385254
Synonyms
LGS glycogen synthase, liver
Viability
No data available
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (13) Measurements chart (307) All data table (579)
Expression & images (45) Disease models (0) Histopathology (5) Order (1)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
increased erythrocyte cell number Gys2tm1a(KOMP)Wtsi HOM Early adult 9.77×10-06
abnormal vibrissa morphology Gys2tm1a(KOMP)Wtsi HOM Early adult 4.19×10-05
abnormal coat/ hair morphology Gys2tm1a(KOMP)Wtsi HOM   Early adult 8.08×10-07
increased circulating calcium level Gys2tm1a(KOMP)Wtsi HOM Early adult 2.23×10-06
increased total body fat amount Gys2tm1a(KOMP)Wtsi HOM Early adult 4.36×10-06
increased circulating total protein level Gys2tm1a(KOMP)Wtsi HOM Early adult 2.72×10-06
decreased circulating glycerol level Gys2tm1a(KOMP)Wtsi HOM Early adult 3.36×10-06
decreased body weight Gys2tm1a(KOMP)Wtsi HOM Early adult 1.20×10-15
increased circulating sodium level Gys2tm1a(KOMP)Wtsi HOM   Early adult 1.20×10-11
decreased circulating glucose level Gys2tm1a(KOMP)Wtsi HOM Early adult 2.55×10-26
increased circulating chloride level Gys2tm1a(KOMP)Wtsi HOM Early adult 2.35×10-06
increased bone mineral density Gys2tm1a(KOMP)Wtsi HOM Early adult 3.67×10-05
increased lean body mass Gys2tm1a(KOMP)Wtsi HOM Early adult 1.27×10-05

Download data as:  TSV  XLS

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Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 5 No  (4/583) N/A
Aorta 5 No  (1/583) N/A
Blood vessel 5 No N/A
Bone 5 No N/A
Brain 5 No  (4/583) N/A
Brainstem 5 No  (2/583) N/A
Brown adipose tissue 5 No N/A
Cartilage tissue 5 No  (1/583) N/A
Cerebellum 5 No  (3/583) N/A
Cerebral cortex 5 No  (2/583) N/A
Eye 5 No N/A
Gall bladder 5 No N/A
Heart 5 No  (2/583) N/A
Hippocampus 5 No  (3/583) N/A
Hypothalamus 5 No  (2/583) N/A
Kidney 5 No  (21/583) N/A
Large intestine 5 No  (10/583) N/A
Liver 5 No N/A
Lower urinary tract 5 No  (1/583) N/A
Lung 5 No  (2/583) N/A
Lymph node 5 No  (1/583) N/A
Mammary gland 5 No N/A
Esophagus 5 No N/A
Olfactory lobe 5 No  (2/583) N/A
Ovary 5 No  (1/583) N/A
Oviduct 5 No N/A
Pancreas 5 No  (5/583)  (1/5) N/A
Parathyroid gland 5 No  (1/563) N/A
Peripheral nervous system 5 No  (2/583) N/A
Peyer's patch 5 No  (1/176) N/A
Pituitary gland 5 No  (1/583) N/A
Prostate gland 5 No  (12/583) N/A
Skeletal muscle tissue 5 No N/A
Skin 5 No  (1/583) N/A
Small intestine 5 No  (9/583) N/A
Spinal cord 5 No  (3/583) N/A
Spleen 5 No  (3/583) N/A
Stomach 5 No  (13/583) N/A
Striatum 5 No  (3/583) N/A
Testis 5 No  (6/583)  (2/5) N/A
Thymus 5 No  (1/583) N/A
Thyroid gland 5 No  (17/583) N/A
Trachea 5 No  (3/583) N/A
Uterus 5 No  (1/5) N/A
White adipose tissue 5 No N/A
LacZ Wholemount Images
LacZ Section Images
LacZ Section Images
Gys2tm1a(KOMP)Wtsi
uterus, HET, Female, WTSI
Gys2tm1a(KOMP)Wtsi
testis, HET, Male, WTSI
Gys2tm1a(KOMP)Wtsi
pancreas, HET, Female, WTSI
Gys2tm1a(KOMP)Wtsi
thyroid gland, HET, Female, WTSI
Gys2tm1a(KOMP)Wtsi
kidney, HET, Female, WTSI
Gys2tm1a(KOMP)Wtsi
uterus, HET, Female, WTSI
Gys2tm1a(KOMP)Wtsi
testis, HET, Male, WTSI
Gys2tm1a(KOMP)Wtsi
pancreas, HET, Female, WTSI
Gys2tm1a(KOMP)Wtsi
kidney, HET, Female, WTSI
Gys2tm1a(KOMP)Wtsi
uterus, HET, Female, WTSI
Gys2tm1a(KOMP)Wtsi
testis, HET, Male, WTSI
Gys2tm1a(KOMP)Wtsi
thyroid gland, HET, Female, WTSI
Gys2tm1a(KOMP)Wtsi
kidney, HET, Female, WTSI
No Embryo expression data was found for this gene.

 Associated Images

thumbnail
Histopathology
14 Images
Legacy Phenotype Associated Images
Gys2tm1a(KOMP)Wtsi
head, HOM, Female, WTSI
Gys2tm1a(KOMP)Wtsi
body, HOM, Female, WTSI
Gys2tm1a(KOMP)Wtsi
forearm, HOM, Female, WTSI
Gys2tm1a(KOMP)Wtsi
body, HOM, Female, WTSI
Gys2tm1a(KOMP)Wtsi
head, HOM, Female, WTSI

View all 131 images

Gys2tm1a(KOMP)Wtsi
back skin, HOM, Female, WTSI
Gys2tm1a(KOMP)Wtsi
back skin, HOM, Female, WTSI
Gys2tm1a(KOMP)Wtsi
back skin, HOM, Female, WTSI

 Disease Models

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 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Spleen - hyperplasia Gys2tm1a(KOMP)Wtsi HOM Early adult
Spleen - MPATH diagnostic term extramedullary hemopoiesis Gys2tm1a(KOMP)Wtsi HOM Early adult
Liver - lipid deposition Gys2tm1a(KOMP)Wtsi HOM Early adult
Liver - iron deposition Gys2tm1a(KOMP)Wtsi HOM Early adult
Liver - process of degenerative change Gys2tm1a(KOMP)Wtsi HOM Early adult

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Gys2tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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