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Gene: Pabpc4

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Name
poly(A) binding protein, cytoplasmic 4
MGI ID
MGI:2385206
Synonyms
N/A
Viability
Data available
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (7) Measurements chart (254) All data table (627)
Expression & images (45) Disease models (0) Order (4)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal spine curvature Pabpc4tm1a(KOMP)Wtsi HOM Early adult 5.04×10-05
decreased circulating free fatty acids level Pabpc4tm1a(KOMP)Wtsi HOM Early adult 4.57×10-12
increased circulating iron level Pabpc4tm1a(KOMP)Wtsi HOM Early adult 1.48×10-05
increased heart weight Pabpc4tm1a(KOMP)Wtsi HOM Early adult 1.60×10-06
decreased circulating cholesterol level Pabpc4tm1a(KOMP)Wtsi HOM Early adult 6.72×10-07
decreased body length Pabpc4tm1e(KOMP)Wtsi HOM Early adult 1.82×10-05
decreased circulating HDL cholesterol level Pabpc4tm1a(KOMP)Wtsi HOM Early adult 2.60×10-06

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (4/583)  (2/2) N/A
Aorta 2 No  (1/583) N/A
Blood vessel 2 No N/A
Bone 2 No N/A
Brain 2 No  (4/583)  (2/2) N/A
Brainstem 2 No  (2/583) N/A
Brown adipose tissue 2 No  (2/2) N/A
Cartilage tissue 2 No  (1/583)  (2/2) N/A
Cerebellum 2 No  (3/583) N/A
Cerebral cortex 2 No  (2/583) N/A
Eye 2 No N/A
Gall bladder 2 No  (2/2) N/A
Heart 2 No  (2/583)  (2/2) N/A
Hippocampus 2 No  (3/583) N/A
Hypothalamus 2 No  (2/583) N/A
Kidney 2 No  (21/583)  (2/2) N/A
Large intestine 2 No  (10/583)  (2/2) N/A
Liver 2 No  (2/2) N/A
Lower urinary tract 2 No  (1/583)  (2/2) N/A
Lung 2 No  (2/583)  (2/2) N/A
Lymph node 2 No  (1/583)  (2/2) N/A
Mammary gland 2 No N/A
Esophagus 2 No  (2/2) N/A
Olfactory lobe 2 No  (2/583) N/A
Ovary 2 No  (1/583)  (1/2) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/583)  (2/2) N/A
Parathyroid gland 2 No  (1/563)  (1/2) N/A
Peripheral nervous system 2 No  (2/583)  (2/2) N/A
Peyer's patch 2 No  (1/176)  (2/2) N/A
Pituitary gland 2 No  (1/583)  (2/2) N/A
Prostate gland 2 No  (12/583)  (1/2) N/A
Skeletal muscle tissue 2 No  (2/2) N/A
Skin 2 No  (1/583)  (2/2) N/A
Small intestine 2 No  (9/583)  (2/2) N/A
Spinal cord 2 No  (3/583)  (2/2) N/A
Spleen 2 No  (3/583)  (2/2) N/A
Stomach 2 No  (13/583)  (2/2) N/A
Striatum 2 No  (3/583) N/A
Testis 2 No  (6/583)  (1/2) N/A
Thymus 2 No  (1/583)  (2/2) N/A
Thyroid gland 2 No  (17/583)  (2/2) N/A
Trachea 2 No  (3/583)  (2/2) N/A
Uterus 2 No  (1/2) N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
LacZ Section Images
LacZ Section Images
Pabpc4tm1e(KOMP)Wtsi
brain, HET, Female, WTSI
Pabpc4tm1e(KOMP)Wtsi
skin, skin muscle, HET, Female, WTSI
Pabpc4tm1e(KOMP)Wtsi
gall bladder, liver, HET, Female, WTSI
Pabpc4tm1e(KOMP)Wtsi
small intestine, peyer's patch, HET, Female, WTSI
Pabpc4tm1e(KOMP)Wtsi
large intestine, HET, Female, WTSI

View all 27 images

Pabpc4tm1e(KOMP)Wtsi
gall bladder, liver, HET, Female, WTSI
Pabpc4tm1e(KOMP)Wtsi
small intestine, peyer's patch, HET, Female, WTSI
Pabpc4tm1e(KOMP)Wtsi
large intestine, HET, Female, WTSI
Pabpc4tm1e(KOMP)Wtsi
urinary bladder, prostate gland, lower urinary tract, HET, Male, WTSI
Pabpc4tm1e(KOMP)Wtsi
urinary bladder, lower urinary tract, HET, Female, WTSI

View all 17 images

Pabpc4tm1e(KOMP)Wtsi
gall bladder, liver, HET, Female, WTSI
Pabpc4tm1e(KOMP)Wtsi
small intestine, peyer's patch, HET, Female, WTSI
Pabpc4tm1e(KOMP)Wtsi
large intestine, HET, Female, WTSI
Pabpc4tm1e(KOMP)Wtsi
oesophagus, HET, Female, WTSI
Pabpc4tm1e(KOMP)Wtsi
small intestine, peyer's patch, HET, Female, WTSI
Pabpc4tm1e(KOMP)Wtsi
thymus, HET, Female, WTSI
Pabpc4tm1e(KOMP)Wtsi
spleen, HET, Female, WTSI
Pabpc4tm1e(KOMP)Wtsi
mesenteric lymph node, lymph node, HET, Female, WTSI
Pabpc4tm1e(KOMP)Wtsi
brain, HET, Female, WTSI
Pabpc4tm1e(KOMP)Wtsi
brain, HET, Female, WTSI
Pabpc4tm1e(KOMP)Wtsi
peripheral nervous system, pituitary gland, HET, Female, WTSI
Pabpc4tm1e(KOMP)Wtsi
spinal cord, HET, Male, WTSI
Pabpc4tm1e(KOMP)Wtsi
urinary bladder, prostate gland, lower urinary tract, HET, Male, WTSI
Pabpc4tm1e(KOMP)Wtsi
uterus, ovary, oviduct, HET, Female, WTSI
Pabpc4tm1e(KOMP)Wtsi
testis, HET, Male, WTSI
Pabpc4tm1e(KOMP)Wtsi
inguinal fat pad, mammary gland, HET, Female, WTSI
Pabpc4tm1e(KOMP)Wtsi
skeletal muscle tissue, cartilage tissue, HET, Female, WTSI
Pabpc4tm1e(KOMP)Wtsi
brown adipose tissue, HET, Female, WTSI
Pabpc4tm1e(KOMP)Wtsi
urinary bladder, prostate gland, lower urinary tract, HET, Male, WTSI
Pabpc4tm1e(KOMP)Wtsi
urinary bladder, lower urinary tract, HET, Female, WTSI
Pabpc4tm1e(KOMP)Wtsi
kidney, HET, Female, WTSI
Pabpc4tm1e(KOMP)Wtsi
inguinal fat pad, mammary gland, HET, Female, WTSI
Pabpc4tm1e(KOMP)Wtsi
brown adipose tissue, HET, Female, WTSI
Pabpc4tm1e(KOMP)Wtsi
heart, HET, Female, WTSI
Pabpc4tm1e(KOMP)Wtsi
skeletal muscle tissue, blood vessel, HET, Female, WTSI
Pabpc4tm1e(KOMP)Wtsi
thyroid gland, trachea, parathyroid gland, HET, Female, WTSI
Pabpc4tm1e(KOMP)Wtsi
adrenal gland, HET, Female, WTSI
Pabpc4tm1e(KOMP)Wtsi
inguinal fat pad, mammary gland, HET, Female, WTSI
Pabpc4tm1e(KOMP)Wtsi
urinary bladder, prostate gland, lower urinary tract, HET, Male, WTSI
Pabpc4tm1e(KOMP)Wtsi
skin, skin muscle, HET, Female, WTSI
Pabpc4tm1e(KOMP)Wtsi
inguinal fat pad, mammary gland, HET, Female, WTSI
Pabpc4tm1e(KOMP)Wtsi
skeletal muscle tissue, cartilage tissue, HET, Female, WTSI
Pabpc4tm1e(KOMP)Wtsi
skeletal muscle tissue, blood vessel, HET, Female, WTSI
Pabpc4tm1e(KOMP)Wtsi
lung, HET, Female, WTSI
Pabpc4tm1e(KOMP)Wtsi
thyroid gland, trachea, parathyroid gland, HET, Female, WTSI
No Embryo expression data was found for this gene.

 Associated Images

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X-ray: XRay Images Whole Body Dorso Ventral
14 Images
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X-ray: XRay Images Skull Lateral Orientation
14 Images
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X-ray: XRay Images Forepaw
14 Images
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X-ray: XRay Images Whole Body Lateral Orientation
15 Images
thumbnail
X-ray: XRay Images Skull Dorso Ventral Orientation
14 Images
Legacy Phenotype Associated Images
Pabpc4tm1e(KOMP)Wtsi
forearm, HOM, Female, WTSI
Pabpc4tm1e(KOMP)Wtsi
body, HOM, Male, WTSI
Pabpc4tm1e(KOMP)Wtsi
forearm, HOM, Male, WTSI
Pabpc4tm1e(KOMP)Wtsi
body, HOM, Male, WTSI
Pabpc4tm1e(KOMP)Wtsi
body, HOM, Male, WTSI

View all 226 images

Pabpc4tm1e(KOMP)Wtsi
eye, narrow eye opening, HOM, Female, WTSI
Pabpc4tm1e(KOMP)Wtsi
eye, cornea/lens fusion, corneal opacity, HOM, Female, WTSI
Pabpc4tm1e(KOMP)Wtsi
eye, corneal opacity, HOM, Female, WTSI
Pabpc4tm1a(KOMP)Wtsi
corneal opacity, HOM, Female, WTSI
Pabpc4tm1a(KOMP)Wtsi
left eye, HOM, Female, WTSI
Pabpc4tm1a(KOMP)Wtsi
back skin, HOM, Female, WTSI
Pabpc4tm1e(KOMP)Wtsi
back skin, HOM, Female, WTSI
Pabpc4tm1a(KOMP)Wtsi
tail, abnormal tail morphology, WT, Female, WTSI

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Pabpc4tm361408(L1L2_Bact_P) Targeting vectors
Pabpc4tm1e(KOMP)Wtsi Targeted, non-conditional allele Mice
Pabpc4tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Pabpc4tm36686(L1L2_Bact_P) Targeting vectors

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