Ahcyl1 | S-adenosylhomocysteine hydrolase-like 1

GeneMGI:2385184Synonyms: IRBIT, Ahcy-rs3, +2 more

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Vision/eye Hematopoietic system Skeleton

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased mean platelet volume1 supporting datasetAhcyl1tm1a(EUCOMM)WtsihomozygoteEarly adult2.57x10-5 
abnormal cornea morphology1 supporting datasetAhcyl1tm1a(EUCOMM)WtsihomozygoteEarly adult3.41x10-5 
abnormal retina morphology1 supporting datasetAhcyl1tm1a(EUCOMM)WtsihomozygoteEarly adult4.58x10-5 
increased circulating alkaline phosphatase level1 supporting datasetAhcyl1tm1a(EUCOMM)WtsihomozygoteEarly adult2.13x10-7 
increased bone mineral content1 supporting datasetAhcyl1tm1a(EUCOMM)WtsihomozygoteEarly adult5.54x10-6 
increased circulating thyroxine level1 supporting datasetAhcyl1tm1a(EUCOMM)WtsihomozygoteEarly adult1.95x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  










* This parameter was manually assessed for significance.
Download data as:  

lacZ Expression

Associated images

Loading...

Histopathology

IMPC related publications

Loading...

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

Ahcyl1tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Ahcyl1tm2a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter