Gene Summary

Name:
BTB (POZ) domain containing 3
Synonyms:
N/A

IMPC Data Collections

IMPC Phenotype Summary

Significant
Not Significant
Not tested

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

Phenotype System Allele Zyg Sex Life Stage P Value
abnormal heart left ventricle morphology Btbd3tm1b(EUCOMM)Hmgu HOM Early adult 3.25×10-05
enlarged thyroid gland Btbd3tm1b(EUCOMM)Hmgu HOM Early adult 0.00
abnormal thyroid gland morphology Btbd3tm1b(EUCOMM)Hmgu HOM Early adult 0.00
abnormal vertebrae morphology Btbd3tm1b(EUCOMM)Hmgu HOM Early adult 1.98×10-05
abnormal vertebral arch morphology Btbd3tm1b(EUCOMM)Hmgu HOM   Early adult 1.17×10-05
decreased body weight Btbd3tm1b(EUCOMM)Hmgu HOM   Early adult 1.90×10-05

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

lacZ Expression

An assay measuring the expression of lacZ shows the tissue where the gene is expressed.

Anatomy Images Zygosity Mutant Expr
Adrenal gland  Section images heterozygote 0.0% (0 of 5)
Aorta  Section images heterozygote 40% (2 of 5)
Bone  Section images heterozygote 40% (2 of 5)
Brain  Section images heterozygote 60% (3 of 5)
Brainstem  Section images heterozygote 40% (2 of 5)
Brown adipose tissue  Section images heterozygote 0.0% (0 of 5)
Cartilage tissue  Section images heterozygote 40% (2 of 5)
Cecum  Section images heterozygote Not available
Cerebellum  Section images heterozygote 40% (2 of 5)
Cerebral cortex  Section images heterozygote 40% (2 of 5)
Chest bone  Section images heterozygote 40% (2 of 5)
Colon  Section images heterozygote Not available
Cranium  Section images heterozygote 0.0% (0 of 5)
Diaphragm  Section images heterozygote 40% (2 of 5)
Duodenum  Section images heterozygote 40% (2 of 5)
Esophagus  Section images heterozygote 40% (2 of 5)
Eye  Section images heterozygote 40% (2 of 5)
Gall bladder  Section images heterozygote 0.0% (0 of 5)
Harderian gland  Section images heterozygote 20% (1 of 5)
Heart  Section images heterozygote 40% (2 of 5)
Hindlimb  Section images heterozygote 40% (2 of 5)
Hippocampus  Section images heterozygote 40% (2 of 5)
Hypothalamus  Section images heterozygote 40% (2 of 5)
Ileum  Section images heterozygote Not available
Jejunum  Section images heterozygote Not available
Kidney  Section images heterozygote 40% (2 of 5)
Large intestine  Section images heterozygote 40% (2 of 5)
Liver  Section images heterozygote 0.0% (0 of 5)
Lower urinary tract  Section images heterozygote 40% (2 of 5)
Lung  Section images heterozygote 0.0% (0 of 5)
Lymph node  Section images heterozygote 0.0% (0 of 5)
Mammary gland  Section images heterozygote 0.0% (0 of 5)
Olfactory lobe  Section images heterozygote 40% (2 of 5)
Oral epithelium  Section images heterozygote 40% (2 of 5)
Ovary  Section images heterozygote 20% (1 of 5)
Oviduct  Section images heterozygote 20% (1 of 5)
Pancreas  Section images heterozygote 0.0% (0 of 5)
Parathyroid gland  Section images heterozygote 40% (2 of 5)
Penis  Section images heterozygote 20% (1 of 5)
Peripheral nervous system  Section images heterozygote 40% (2 of 5)
Pituitary gland  Section images heterozygote 40% (2 of 5)
Prostate gland  Section images heterozygote 20% (1 of 5)
Quadriceps  Section images heterozygote 40% (2 of 5)
Skeletal muscle  Section images heterozygote 40% (2 of 5)
Skin  Section images heterozygote 40% (2 of 5)
Small intestine  Section images heterozygote 40% (2 of 5)
Spinal cord  Section images heterozygote 0.0% (0 of 5)
Spleen  Section images heterozygote 0.0% (0 of 5)
Stomach  Section images heterozygote 40% (2 of 5)
Striatum  Section images heterozygote 40% (2 of 5)
Submandibular gland  Section images heterozygote 40% (2 of 5)
Testis  Section images heterozygote 20% (1 of 5)
Thymus  Section images heterozygote 0.0% (0 of 5)
Thyroid gland  Section images heterozygote 40% (2 of 5)
Tongue  Section images heterozygote 40% (2 of 5)
Trachea  Section images heterozygote 40% (2 of 5)
Urinary bladder  Section images heterozygote 40% (2 of 5)
Uterus  Section images heterozygote 20% (1 of 5)
Vagina  Section images heterozygote 20% (1 of 5)
Vascular system  Section images heterozygote 40% (2 of 5)
White adipose tissue  Section images heterozygote 0.0% (0 of 5)
Blood N/A heterozygote Not available
Bone marrow N/A heterozygote Not available
Epididymis N/A heterozygote Not available
Gonadal fat pad N/A heterozygote Not available
Main olfactory bulb N/A heterozygote Not available
Mesenteric adipose tissue N/A heterozygote Not available
Mesenteric lymph node N/A heterozygote Not available
Midbrain N/A heterozygote Not available
Parotid gland N/A heterozygote Not available
Peyer's patch N/A heterozygote Not available
Sciatic nerve N/A heterozygote Not available
Stomach pyloric region N/A heterozygote Not available
Sublingual gland N/A heterozygote Not available
Thalamus N/A heterozygote Not available
Trigeminal V nerve N/A heterozygote Not available
Vas deferens N/A heterozygote Not available
Vesicular gland N/A heterozygote Not available
No Embryo expression data was found for this gene.

Background staining occurs in wild type mice and embryos at an incidental rate.

Anatomy Background staining in controls (WT)
adrenal gland 0.68% (4 of 584)
aorta 0.17% (1 of 584)
blood 0.0%
bone 0.0%
bone marrow 0.0%
brain 0.68% (4 of 584)
brainstem 0.34% (2 of 584)
brown adipose tissue 0.0%
cartilage tissue 0.17% (1 of 584)
cecum 2.97% (11 of 370)
cerebellum 0.51% (3 of 584)
cerebral cortex 0.34% (2 of 584)
chest bone Unavailable
colon 8.73% (11 of 126)
cranium
diaphragm 0.0%
duodenum 0.79% (1 of 126)
epididymis 12.78% (17 of 133)
esophagus 1.72% (7 of 408)
eye 0.0%
gall bladder 0.0%
gonadal fat pad 0.0%
harderian gland 0.0%
heart 0.34% (2 of 584)
hindlimb 0.0%
hippocampus 0.51% (3 of 584)
hypothalamus 0.34% (2 of 584)
ileum 10.32% (13 of 126)
jejunum 3.97% (5 of 126)
kidney 3.6% (21 of 584)
large intestine 1.71% (10 of 584)
liver 0.0%
lower urinary tract 0.17% (1 of 584)
lung 0.34% (2 of 584)
lymph node 0.17% (1 of 584)
main olfactory bulb 0.0%
mammary gland 0.0%
mesenteric adipose tissue 0.0%
mesenteric lymph node 0.0%
midbrain 0.0%
olfactory lobe 0.34% (2 of 584)
oral epithelium 0.0%
ovary 0.17% (1 of 584)
oviduct 0.0%
pancreas 0.86% (5 of 584)
parathyroid gland 0.18% (1 of 562)
parotid gland 0.0%
penis 0.0%
peripheral nervous system 0.34% (2 of 584)
peyers patch 0.0%
pituitary gland 0.17% (1 of 584)
prostate gland 2.05% (12 of 584)
quadriceps 0.0%
sciatic nerve 0.0%
skeletal muscle 0.0%
skin 0.17% (1 of 584)
small intestine 1.54% (9 of 584)
spinal cord 0.51% (3 of 584)
spleen 0.51% (3 of 584)
stomach 2.05% (12 of 584)
stomach pyloric region 0.0%
striatum 0.51% (3 of 584)
sublingual gland 0.0%
submandibular gland 1.53% (2 of 131)
testis 1.03% (6 of 584)
thalamus 0.0%
thymus 0.17% (1 of 584)
thyroid gland 2.74% (16 of 584)
tongue 3.97% (5 of 126)
trachea 0.51% (3 of 584)
trigeminal v nerve 0.0%
urinary bladder 0.0%
uterus 0.0%
vagina 0.0%
vas deferens 3.67% (14 of 381)
vascular system 0.0%
vesicular gland 0.0%
white adipose tissue 0.0%
No Embryo expression data was found for this gene.

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Adult LacZ

LacZ Images Section

120 Images

X-ray

XRay Images Hind Leg and Hip

30 Images

X-ray

XRay Images Whole Body Dorso Ventral

30 Images

X-ray

XRay Images Forepaw

15 Images

X-ray

XRay Images Skull Dorso Ventral Orientation

15 Images

X-ray

XRay Images Skull Lateral Orientation

15 Images

X-ray

XRay Images Whole Body Lateral Orientation

15 Images

Human diseases caused by Btbd3 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Btbd3 by phenotypic similarity.

Disease Similarity of
phenotypes
Matching phenotypes Source
Thyroid Cancer, Nonmedullary, 1
Non-medullary thyroid carcinoma, Goiter, Papillary thyroid carcinoma OMIM:188550
Thyroid Dyshormonogenesis 3
Compensated hypothyroidism, Increased T3/T4 ratio, Goiter, Thyroid carcinoma OMIM:274700
Thyroid Hormone Resistance, Generalized, Autosomal Recessive
Impaired sensitivity to thyroid hormone, Goiter, Small for gestational age OMIM:274300
Thyroid Dyshormonogenesis 5
Hypothyroidism, Goiter OMIM:274900
Thyroid Dyshormonogenesis 4
Hypothyroidism, Goiter OMIM:274800
Thyroid Dyshormonogenesis 2A
Hypothyroidism, Goiter, Thyroid defect in oxidation and organification of iodide OMIM:274500
Goiter, Multinodular 1, With Or Without Sertoli-Leydig Cell Tumors
Euthyroid multinodular goiter, Papillary thyroid carcinoma OMIM:138800
Thyroid Cancer, Nonmedullary, 4
Non-medullary thyroid carcinoma, Goiter OMIM:616534
Thyroid Hormone Resistance, Generalized, Autosomal Dominant
Impaired sensitivity to thyroid hormone, Goiter, Increased circulating free T3 OMIM:188570
Thyroid Hormone Plasma Membrane Transport Defect
Euthyroid hyperthyroxinemia, Goiter OMIM:188560
Deiodinase, iodothyronine, type I
Euthyroid hyperthyroxinemia, Goiter OMIM:147892
Pendred Syndrome
Compensated hypothyroidism, Thyroid carcinoma, Goiter OMIM:274600
Ectodermal Dysplasia, Hypohidrotic, With Hypothyroidism And Agenesis Of The Corpus Callosum
Goiter, Primary hypothyroidism OMIM:225040
Fetal Iodine Deficiency Disorder
Congenital goiter, Congenital hypothyroidism OMIM:228355
Goiter, Multinodular 2
Euthyroid multinodular goiter OMIM:300273
Hyperthyroidism, Nonautoimmune
Small for gestational age, Goiter, Hyperthyroidism, Thyroid hyperplasia OMIM:609152
Sacral Agenesis With Vertebral Anomalies
Absence of the sacrum, Abnormal vertebral morphology OMIM:615709
Glutaric Aciduria Iii
Goiter, Hyperthyroidism, Failure to thrive OMIM:231690
Rhabdomyosarcoma, Embryonal, 2
Ovarian thecoma, Goiter, Thyroid nodule, Multinodular goiter OMIM:180295
Blepharochalasis And Double Lip
Goiter OMIM:109900
Familial Papillary Or Follicular Thyroid Carcinoma
Follicular thyroid carcinoma, Papillary thyroid carcinoma, Goiter, Nodular goiter ORPHA:319487
Bangstad Syndrome
Small for gestational age, Goiter, Primary gonadal insufficiency, Insulin-resistant diabetes mell... OMIM:210740
Familial Scheuermann Disease
Kyphosis, Abnormal form of the vertebral bodies ORPHA:3135
Familial Hyperthyroidism Due To Mutations In Tsh Receptor
Goiter, Weight loss, Activating thyroid-stimulating hormone receptor defect, Small for gestationa... ORPHA:424
Ciliary Dyskinesia, Primary, 37
Dextrocardia, Goiter, Situs inversus totalis, Hypothyroidism OMIM:617577
Retinal Dystrophy With Or Without Extraocular Anomalies
Goiter, Premature ovarian insufficiency OMIM:617175
Thyrotoxic Periodic Paralysis, Susceptibility To, 2
Goiter, Hyperthyroidism, Weight loss OMIM:613239
Graves Disease, Susceptibility To, 1
Graves disease, Goiter, Weight loss OMIM:275000
Familial Papillary Thyroid Carcinoma With Renal Papillary Neoplasia
Papillary thyroid carcinoma, Goiter, Nodular goiter ORPHA:97290
Multinodular Goiter-Cystic Kidney-Polydactyly Syndrome
Multinodular goiter ORPHA:2091
Thyrotoxic Periodic Paralysis, Susceptibility To, 1
Goiter, Hyperthyroidism, Weight loss OMIM:188580
Goiter, Multinodular, Cystic Renal Disease, And Digital Anomalies
Multinodular goiter OMIM:138790
Familial Gestational Hyperthyroidism
Goiter, Weight loss, Activating thyroid-stimulating hormone receptor defect, Thyrotoxicosis with ... ORPHA:99819
Maffucci Syndrome
Scoliosis, Neoplasm of the parathyroid gland, Goiter, Ovarian neoplasm, Neoplasm of the adrenal c... ORPHA:163634
Thyroid Dyshormonogenesis 1
Hypothyroidism, Goiter OMIM:274400
Myxedema
Hypothyroidism, Goiter, Elevated circulating thyroid-stimulating hormone concentration OMIM:255900
Familial Thyroid Dyshormonogenesis
Increased radioactive iodine uptake, Goiter, Decreased circulating T4 level, Elevated circulating... ORPHA:95716
Primary Basilar Invagination
Abnormality of the cervical spine, Short neck, Abnormal vertebral morphology ORPHA:2285
Thyroid Lymphoma
Hypothyroidism, Goiter, Hashimoto thyroiditis, Hyperthyroidism ORPHA:97285
Permanent Congenital Hypothyroidism
Hypothyroidism, Thyroid dysgenesis, Goiter ORPHA:226292
Medullary Thyroid Carcinoma
Elevated calcitonin, Pheochromocytoma, Weight loss, Primary hyperparathyroidism, Nodular goiter, ... ORPHA:1332
Ascher Syndrome
Hypothyroidism, Goiter ORPHA:1253
Thyrocerebroretinal Syndrome
Goiter OMIM:274240
Pendred Syndrome
Thyroid carcinoma, Hypothyroidism, Goiter, Hyperparathyroidism ORPHA:705
Anaplastic Thyroid Carcinoma
Anaplastic thyroid carcinoma, Goiter, Weight loss, Nodular goiter ORPHA:142
Thyrocerebrorenal Syndrome
Euthyroid goiter ORPHA:3327
Hypothyroidism, Congenital, Nongoitrous, 5
Hypothyroidism, Congenital hypothyroidism, Ectopic thyroid, Thyroid hypoplasia OMIM:225250
Cancer, Alopecia, Pigment Dyscrasia, Onychodystrophy, And Keratoderma
Multinodular goiter OMIM:618373
Pseudohypoparathyroidism With Albright Hereditary Osteodystrophy
Scoliosis, Goiter, Abnormal calcium-phosphate regulating hormone level, Abnormal testis morpholog... ORPHA:457059
Cowden Syndrome 5
Scoliosis, Hydrocele testis, Ovarian cyst, Goiter, Thyroiditis, Kyphosis, Hypothyroidism, Thyroid... OMIM:615108
Congenital Hypothyroidism Due To Maternal Intake Of Antithyroid Drugs
Goiter, Decreased circulating T4 level, Elevated circulating thyroid-stimulating hormone concentr... ORPHA:226313
Cowden Syndrome 6
Scoliosis, Hydrocele testis, Ovarian cyst, Goiter, Thyroiditis, Kyphosis, Hypothyroidism, Thyroid... OMIM:615109
Hypothyroidism, Congenital, Nongoitrous, 1
Hypothyroidism, Congenital hypothyroidism, Elevated circulating thyroid-stimulating hormone conce... OMIM:275200
Hypothyroidism, Congenital, Nongoitrous, 9
Central hypothyroidism, Inappropriately normal thyroid-stimulating hormone level, Decreased circu... OMIM:301035
Osteomesopyknosis
Scoliosis, Sclerotic vertebral body, Kyphosis, Abnormal form of the vertebral bodies ORPHA:2777
Steroid-Responsive Encephalopathy Associated With Autoimmune Thyroiditis
Hypothyroidism, Goiter, Hashimoto thyroiditis ORPHA:83601
Genetic Transient Congenital Hypothyroidism
Goiter, Decreased circulating T4 level, Abnormal radioactive iodine uptake test result, Elevated ... ORPHA:226316
Multiple Endocrine Neoplasia, Type Iib
Scoliosis, Parathyroid hyperplasia, Hyperlordosis, Nodular goiter, Pheochromocytoma, Kyphosis, Fa... OMIM:162300
Cowden Syndrome 1
Scoliosis, Hydrocele testis, Ovarian cyst, Goiter, Thyroiditis, Kyphosis, Hypothyroidism, Ovarian... OMIM:158350
Multicentric Osteolysis-Nodulosis-Arthropathy Spectrum
Atrial septal defect, Ventricular septal defect, Abnormal form of the vertebral bodies, Polycysti... ORPHA:371428
Congenital Hypothyroidism
Goiter, Hypothyroidism, Abnormal pericardium morphology, Abnormality of the thyroid gland, Hypogo... ORPHA:442
Carney Complex, Type 1
Elevated circulating growth hormone concentration, Pheochromocytoma, Cardiac myxoma, Thyroid foll... OMIM:160980
Pediatric-Onset Graves Disease
Puberty and gonadal disorders, Graves disease, Increased circulating T4 level, Goiter, Thyrotoxic... ORPHA:525731
Isolated Thyroid-Stimulating Hormone Deficiency
Goiter, Increased pituitary glycoprotein hormone alpha subunit level, Decreased circulating T4 le... ORPHA:90674
Mccune-Albright Syndrome
Scoliosis, Ovarian cyst, Abnormal endocrine physiology, Hyperplasia of the Leydig cells, Elevated... ORPHA:562
Male Hypergonadotropic Hypogonadism-Intellectual Disability-Skeletal Anomalies Syndrome
Abnormal form of the vertebral bodies, Hemivertebrae, Abnormality of the thyroid gland, Type II d... ORPHA:2234
Hypothyroidism, Congenital, Nongoitrous, 2
Thyroid agenesis, Goiter, Hypothyroidism, Elevated circulating thyroid-stimulating hormone concen... OMIM:218700
Tsh-Secreting Pituitary Adenoma
Euthyroid hyperthyroxinemia, Male hypogonadism, Elevated circulating growth hormone concentration... ORPHA:91347
Alstrom Syndrome
Scoliosis, Hyperinsulinemia, Multinodular goiter, Hypergonadotropic hypogonadism, Hypothyroidism,... OMIM:203800
Multiple Endocrine Neoplasia, Type Iia
Increased circulating cortisol level, Pheochromocytoma, Thyroid C cell hyperplasia, Parathyroid a... OMIM:171400
Brain-Lung-Thyroid Syndrome
Compensated hypothyroidism, Atrial septal defect, Ventricular septal defect, Elevated circulating... ORPHA:209905
Resistance To Thyrotropin-Releasing Hormone Syndrome
Overweight, Decreased circulating T4 level, Pituitary hypothyroidism, Decreased circulating free ... ORPHA:99832
Acrodysplasia Scoliosis
Scoliosis, Vertebral segmentation defect, Spina bifida occulta ORPHA:2956
Cowden Syndrome 7
Ductal carcinoma in situ, Papillary thyroid carcinoma, Goiter, Hashimoto thyroiditis OMIM:616858
Multiple Endocrine Neoplasia Type 1
Pancreatic endocrine tumor, Elevated circulating growth hormone concentration, Increased circulat... ORPHA:652
Cowden Syndrome
Scoliosis, Goiter, Kyphosis, Neoplasm of the thyroid gland, Adenoma sebaceum, Abnormality of the ... ORPHA:201
Blepharophimosis-Intellectual Disability Syndrome, Sbbys Type
Cryptorchidism, Thyroid agenesis, Atrial septal defect, Ventricular septal defect, Hypothyroidism... ORPHA:3047
Autosomal Dominant Progressive External Ophthalmoplegia
Goiter, Hypothyroidism, Left ventricular hypertrophy, Failure to thrive, Dilated cardiomyopathy, ... ORPHA:254892
Familial Multinodular Goiter
Ovarian neoplasm, Multinodular goiter, Sertoli cell neoplasm, Testicular seminoma, Thyroid carcinoma ORPHA:276399
Carney Complex
Elevated circulating growth hormone concentration, Increased circulating cortisol level, Cardiac ... ORPHA:1359
Pten Hamartoma Tumor Syndrome
Thyroid adenoma, Thyroid carcinoma, Multinodular goiter ORPHA:306498
Multiple Endocrine Neoplasia Type 2
Hyperlordosis, Parathyroid hyperplasia, Pheochromocytoma, Thyroid C cell hyperplasia, Thyroid nod... ORPHA:653
Pallister-Hall Syndrome
Cryptorchidism, Panhypopituitarism, Adrenal hypoplasia, Ventricular septal defect, Decreased circ... OMIM:146510
Hypothyroidism Due To Tsh Receptor Mutations
Compensated hypothyroidism, Increased radioactive iodine uptake, Decreased circulating T4 level, ... ORPHA:90673
Familial Adenomatous Polyposis
Goiter, Neoplasm of the adrenal gland, Thyroiditis, Hypothyroidism, Abnormality of the thyroid gl... ORPHA:733
Thyroid Ectopia
Hypothyroidism, Abnormality of the thyroid gland, Ectopic thyroid ORPHA:95712
Branchiootorenal Syndrome 1
Euthyroid goiter OMIM:113650
Hypothyroidism Due To Deficient Transcription Factors Involved In Pituitary Development Or Function
Panhypopituitarism, Decreased circulating ACTH level, Decreased circulating follicle stimulating ... ORPHA:226307
Congenital Hemidysplasia With Ichthyosiform Erythroderma And Limb Defects
Scoliosis, Vertebral hypoplasia, Adrenal hypoplasia, Single ventricle, Thyroid hypoplasia, Abnorm... OMIM:308050
Thyroid Hypoplasia
Hypothyroidism, Thyroid hypoplasia ORPHA:95720
Congenital Alveolar Capillary Dysplasia
Pulmonary valve atresia, Atrial septal defect, Abnormal vertebral morphology, Ventricular septal ... ORPHA:210122
Phace Association
Lingual thyroid, Congenital hypothyroidism, Ventricular septal defect OMIM:606519
Phace Syndrome
Abnormal heart morphology, Hypothyroidism, Tetralogy of Fallot, Ectopic thyroid, Abnormal cardiac... ORPHA:42775
Stüve-Wiedemann Syndrome
Scoliosis, Hypothyroidism, Ectopic thyroid, Sacral dimple ORPHA:3206
Myhre Syndrome
Platyspondyly, Cryptorchidism, Atrial septal defect, Ventricular septal defect, Pericardial effus... OMIM:139210
Treacher-Collins Syndrome
Cryptorchidism, Abnormality of the vertebral column, Hypoplasia of the thymus, Thyroid hypoplasia... ORPHA:861
Microcephaly-Facial Dysmorphism-Ocular Anomalies-Multiple Congenital Anomalies Syndrome
Congenital hypothyroidism, Thyroid hypoplasia ORPHA:521445
Holoprosencephaly-Postaxial Polydactyly Syndrome
Cryptorchidism, Adrenal hypoplasia, Thyroid hypoplasia, Abnormal cardiac septum morphology, Abnor... ORPHA:2166
Pallister-Hall Syndrome
Cryptorchidism, Panhypopituitarism, Atrial septal defect, Adrenal hypoplasia, Ventricular septal ... ORPHA:672
Osteogenesis Imperfecta
Scoliosis, Abnormal form of the vertebral bodies, Biconcave vertebral bodies, Abnormal endocardiu... ORPHA:666

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Btbd3

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Btbd3.

No publications found that use IMPC mice or data for Btbd3.

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MGI Allele Allele Type Produced
Btbd3tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice
Btbd3tm1c(EUCOMM)Hmgu Wild type floxed exon (post-Flp) Mice
Btbd3tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Btbd3tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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