Gene: Pex6

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Name
peroxisomal biogenesis factor 6
MGI ID
MGI:2385054
Synonyms
D130055I09Rik
Viability
Embryo viewer
N/A
Other links
Expression & images (0) Disease models (0) Order (5)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
preweaning lethality, complete penetrance Pex6em1(IMPC)Tcp HOM   Early adult 0.00
abnormal optic disk morphology Pex6em1(IMPC)Tcp HET   Early adult 4.11×10-05
abnormal retinal vasculature morphology Pex6em1(IMPC)Tcp HET Early adult 9.07×10-06
impaired pupillary reflex Pex6em1(IMPC)Tcp HET Early adult 1.37×10-06
decreased circulating potassium level Pex6em1(IMPC)Tcp HET Early adult 4.34×10-05
abnormal retinal blood vessel morphology Pex6em1(IMPC)Tcp HET   Early adult 9.01×10-06
persistence of hyaloid vascular system Pex6em1(IMPC)Tcp HET Early adult 7.15×10-05
abnormal iris morphology Pex6em1(IMPC)Tcp HET Early adult 4.03×10-06

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 Expression

Expression data not available

 Associated Images

Eye Morphology: Images Slit Lamp
94 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
Eye Morphology: Images Ophthalmoscopy
101 Images
Gross Pathology and Tissue Collection
8 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Pex6tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Pex6em1(IMPC)Tcp Exon Deletion Mice
Pex6tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Pex6em1(IMPC)Bay Exon Deletion Mice
Pex6tm44758(L1L2_gt0) Targeting vectors

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