Gene Summary
IMPC Data Collections
- Body Weight Measurements
- No Embryo Imaging Data
- Viability Data
The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Krt79.
There are 5 publications which use IMPC produced mice or data.
Title | Journal | IMPC Allele | PubMed ID |
---|---|---|---|
A Genome-Wide Screen in Mice To Identify Cell-Extrinsic Regulators of Pulmonary Metastatic Colonisation. | G3 (Bethesda, Md.) (June 2020) | Krt79tm2b(KOMP)Wtsi | PMC7263671 |
Niche-Specific Factors Dynamically Regulate Sebaceous Gland Stem Cells in the Skin. | Developmental cell (September 2019) | Krt79tm2c(KOMP)Wtsi Krt79tm2b(KOMP)Wtsi | 31564613 |
Large-scale neuroanatomical study uncovers 198 gene associations in mouse brain morphogenesis. | Nature communications (August 2019) | Krt79tm2b(KOMP)Wtsi | PMC6671969 |
Loss of Gata6 causes dilation of the hair follicle canal and sebaceous duct. | Experimental dermatology (September 2018) | Krt79tm2a(KOMP)Wtsi | PMC6529183 |
Hair Follicle Terminal Differentiation Is Orchestrated by Distinct Early and Late Matrix Progenitors. | Cell reports (April 2017) | Krt79tm2a(KOMP)Wtsi Krt79tm2b(KOMP)Wtsi | PMC5482241 |
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
MGI Allele | Allele Type | Produced |
---|---|---|
Krt79tm1e(KOMP)Wtsi | Targeted, non-conditional allele | ES Cells |
Krt79tm2e(KOMP)Wtsi | Targeted, non-conditional allele | ES Cells |
Krt79tm2a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | Mice, Targeting vectors, ES Cells |
Krt79tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | Targeting vectors, ES Cells |
Krt79tm2b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | Mice |
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