Gene: Prmt7

Name protein arginine N-methyltransferase 7

Synonyms 4933402B05Rik

Status ES CellsMice
tm1a
phenotype data available

Links MGI:2384879   Ensembl Gene   Ensembl Orthologs

Viability Homozygous - Subviable

Phenotype associations for Prmt7

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Prmt7 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, incomplete penetrance Prmt7tm1a(EUCOMM)Wtsi HOM Female Male n/a 0.0
decreased lean body mass Prmt7tm1a(EUCOMM)Wtsi HOM Female Male postnatal 1.08E-9
decreased erythrocyte cell number Prmt7tm1a(EUCOMM)Wtsi HOM Male postnatal 2.44E-9
abnormal rib morphology Prmt7tm1a(EUCOMM)Wtsi HOM Female postnatal 8.01E-8

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (1/2)
Aorta 2 No (1/562)
Blood vessel 2 No
Bone 2 No (1/539)
Brain 2 No (5/562) (2/2)
Brainstem 2 No (4/562)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/562) (2/2)
Cerebellum 2 No (4/562)
Cerebral cortex 2 No (5/562)
Eye 2 No (1/562)
Gall bladder 2 No
Heart 2 No (3/562)
Hippocampus 2 No (5/562)
Hypothalamus 2 No (4/562)
Kidney 2 No (19/562)
Large intestine 2 No (12/562)
Liver 2 No
Lower urinary tract 2 No (3/562)
Lung 2 No (3/562)
Lymph node 2 No (1/562)
Mammary gland 2 No
Esophagus 2 No (2/2)
Olfactory lobe 2 No
Ovary 2 No (1/562) (1/2)
Oviduct 2 No (2/562)
Pancreas 2 No (6/562)
Parathyroid gland 2 No (2/540) (1/2)
Peripheral nervous system 2 No (3/562) (2/2)
Peyer's patch 2 No
Pituitary gland 2 No (1/562)
Prostate gland 2 No (5/562)
Skeletal muscle tissue 2 No (2/2)
Skin 2 No (1/562)
Small intestine 2 No (11/562)
Spinal cord 2 No (3/562) (2/2)
Spleen 2 No (4/562)
Stomach 2 No (9/562)
Striatum 2 No (4/562)
Testis 2 No (3/562) (1/2)
Thymus 2 No
Thyroid gland 2 No (16/562)
Trachea 2 No (3/562) (2/2)
Uterus 2 No (2/562)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse respiratory system endocrine system digestive system nervous system set of connective tissues reproductive system musculoskeletal system trunk
No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
nervous system (4)
  • Prmt7tm1a(EUCOMM)Wtsi
    BRAIN, HET, Female, WTSI
  • Prmt7tm1a(EUCOMM)Wtsi
    PERIPHERAL NERVOUS SYSTEM, HET, Female, WTSI
  • Prmt7tm1a(EUCOMM)Wtsi
    BRAIN, HET, Female, WTSI
  • Prmt7tm1a(EUCOMM)Wtsi
    SPINAL CORD, HET, Female, WTSI
trunk (4)
  • Prmt7tm1a(EUCOMM)Wtsi
    OVARY, HET, Female, WTSI
  • Prmt7tm1a(EUCOMM)Wtsi
    TESTIS, HET, Male, WTSI
  • Prmt7tm1a(EUCOMM)Wtsi
    ADRENAL GLAND, HET, Male, WTSI
  • Prmt7tm1a(EUCOMM)Wtsi
    SPINAL CORD, HET, Female, WTSI
reproductive system (3)
  • Prmt7tm1a(EUCOMM)Wtsi
    OVARY, HET, Female, WTSI
  • Prmt7tm1a(EUCOMM)Wtsi
    TESTIS, HET, Male, WTSI
  • Prmt7tm1a(EUCOMM)Wtsi
    PLACENTA, HET, Unsexed, WTSI
endocrine system (2)
  • Prmt7tm1a(EUCOMM)Wtsi
    PARATHYROID GLAND, HET, Female, WTSI
  • Prmt7tm1a(EUCOMM)Wtsi
    ADRENAL GLAND, HET, Male, WTSI
set of connective tissues (1)
  • Prmt7tm1a(EUCOMM)Wtsi
    CARTILAGE TISSUE, HET, Male, WTSI

Associated Images

Legacy Phenotype Associated Images
Xray (146)
  • Prmt7tm1a(EUCOMM)Wtsi
    HEAD, HOM, Female, WTSI
  • Prmt7tm1a(EUCOMM)Wtsi
    HEAD, HOM, Female, WTSI
  • Prmt7tm1a(EUCOMM)Wtsi
    LOWER ARM, HOM, Female, WTSI
  • Prmt7tm1a(EUCOMM)Wtsi
    TRUNK, HOM, Female, WTSI
  • Prmt7tm1a(EUCOMM)Wtsi
    TRUNK, HOM, Female, WTSI

show all 146 images

Eye Morphology (3)
  • Prmt7tm1a(EUCOMM)Wtsi
    EYE, abnormal placement of pupils, mydriasis, impaired pupillary reflex, corneal opacity, cornea/lens fusion, abnormal pupil morphology, HET, Female, WTSI
  • Prmt7tm1a(EUCOMM)Wtsi
    EYE, abnormal pupil morphology, HET, Female, WTSI
  • Prmt7tm1a(EUCOMM)Wtsi
    EYE, cornea/lens fusion, corneal opacity, HET, Female, WTSI
Skin Histopathology (3)
  • Prmt7tm1a(EUCOMM)Wtsi
    FOOT DIGIT 4, HOM, Female, WTSI
  • Prmt7tm1a(EUCOMM)Wtsi
    FOOT DIGIT 4, HOM, Female, WTSI
  • Prmt7tm1a(EUCOMM)Wtsi
    FOOT DIGIT 4, HOM, Female, WTSI

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Prmt7tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Prmt7tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene