Gene: Cdk5rap2

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Name
CDK5 regulatory subunit associated protein 2
MGI ID
MGI:2384875
Synonyms
2900018K03Rik an
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased mean corpuscular hemoglobin Cdk5rap2tm1a(EUCOMM)Wtsi HOM Early adult 2.28×10-25
abnormal cranium morphology Cdk5rap2tm1a(EUCOMM)Wtsi HOM Early adult 5.60×10-06
decreased leukocyte cell number Cdk5rap2tm1a(EUCOMM)Wtsi HOM Early adult 5.95×10-08
decreased body weight Cdk5rap2tm1a(EUCOMM)Wtsi HOM   Early adult 2.08×10-07
increased mean corpuscular volume Cdk5rap2tm1a(EUCOMM)Wtsi HOM Early adult 1.31×10-31
abnormal head morphology Cdk5rap2tm1a(EUCOMM)Wtsi HOM Early adult 3.15×10-05
decreased erythrocyte cell number Cdk5rap2tm1a(EUCOMM)Wtsi HOM   Early adult 4.79×10-05

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
2 No  (4/583) N/A
2 No  (1/583) N/A
2 No N/A
2 No N/A
2 No  (4/583)  (2/2) N/A
2 No  (2/583) N/A
2 No N/A
2 No  (1/583) N/A
2 No  (3/583) N/A
2 No  (2/583) N/A
2 No N/A
2 No N/A
2 No  (2/583) N/A
2 No  (3/583) N/A
2 No  (2/583) N/A
2 No  (21/583)  (2/2) N/A
2 No  (10/583) N/A
2 No N/A
2 No  (1/583) N/A
2 No  (2/583) N/A
2 No  (1/583) N/A
2 No N/A
2 No N/A
2 No  (2/583) N/A
2 No  (1/583) N/A
2 No N/A
2 No  (5/583) N/A
2 No  (1/563) N/A
2 No  (2/583) N/A
2 No  (1/176) N/A
2 No  (1/583) N/A
2 No  (12/583) N/A
2 No N/A
2 No  (1/583) N/A
2 No  (9/583) N/A
2 No  (3/583) N/A
2 No  (3/583) N/A
2 No  (13/583) N/A
2 No  (3/583) N/A
2 No  (6/583)  (1/2) N/A
2 No  (1/583) N/A
2 No  (17/583) N/A
2 No  (3/583) N/A
2 No N/A
2 No N/A
LacZ Section Images
No Embryo expression data was found for this gene.

 Associated Images

Histopathology
8 Images
Legacy Phenotype Associated Images

View all 58 images

 Disease Models

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 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Brain - hypoplasia Cdk5rap2tm1a(EUCOMM)Wtsi HOM Early adult
Spleen - MPATH diagnostic term extramedullary hemopoiesis Cdk5rap2tm1a(EUCOMM)Wtsi HOM Early adult
Spleen - hyperplasia Cdk5rap2tm1a(EUCOMM)Wtsi HOM Early adult
Epididymis - hypoplasia Cdk5rap2tm1a(EUCOMM)Wtsi HOM Early adult
Bone marrow - hyperplasia Cdk5rap2tm1a(EUCOMM)Wtsi HOM Early adult
Testes - hypoplasia Cdk5rap2tm1a(EUCOMM)Wtsi HOM Early adult

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Cdk5rap2tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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