Chpt1 | choline phosphotransferase 1

Physiological systems

19 / 24 physiological systems tested

1 Significantly impacted by the knock-out

 Mortality/aging

18 No significant impact

5 Not tested

Gene metrics:1Significant phenotypes
0Associated diseases
Expression examined in:50Adult tissues
62Embryo tissues

Phenotypes

preweaning lethality, incomplete penetrance3 supporting datasetsChpt1tm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

adrenal glandheterozygoteWholemount images
100% (2/2)0.7% (4/570)
aortaheterozygoteWholemount images
100% (2/2)0.19% (1/533)
boneheterozygoteWholemount images
n/a0% (0/394)
brainheterozygoteWholemount images
100% (2/2)0.86% (5/579)
brainstemheterozygoteWholemount images
100% (2/2)0.41% (2/490)
brown adipose tissueheterozygoteWholemount images
100% (2/2)0% (0/588)
cartilage tissueheterozygoteWholemount images
n/a0.22% (1/454)
cerebellumheterozygoteWholemount images
100% (2/2)0.56% (3/532)
cerebral cortexheterozygoten/a0% (0/2)0.41% (2/491)
esophagusheterozygoten/a0% (0/2)1.67% (7/419)
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Histopathology

IMPC related publications

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Chpt1tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Chpt1tm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Chpt1tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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