Gene: Nepro

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Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
preweaning lethality, complete penetrance Neprotm1.1(KOMP)Vlcg HOM n/a 0.00
abnormal embryo size Neprotm1.1(KOMP)Vlcg HET embryonic day 9.5 0.00
embryonic lethality prior to organogenesis Neprotm1.1(KOMP)Vlcg HOM embryonic day 9.5 0.00
embryonic growth retardation Neprotm1.1(KOMP)Vlcg HET embryonic day 9.5 0.00
embryonic lethality prior to tooth bud stage Neprotm1.1(KOMP)Vlcg HOM embryonic day 12.5 0.00

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2) N/A
Aorta 2 No  (1/2) N/A
Blood 2 No N/A
Bone marrow 2 No  (2/2) N/A
Brain 2 No N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No  (2/2) N/A
Cartilage tissue 2 No N/A
Cecum 2 No  (12/383)  (1/2) N/A
Cerebellum 2 No  (2/2) N/A
Cerebral cortex 2 No N/A
Chest bone 2 No N/A
Colon 2 No  (12/127)  (2/2) N/A
Diaphragm 2 No  (1/2) N/A
Duodenum 2 No  (2/127)  (2/2) N/A
Epididymis 2 No  (18/134)  (1/2) N/A
Esophagus 2 No  (7/415)  (1/2) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Gonadal fat pad 2 No  (1/2) N/A
Harderian gland 2 No  (2/2) N/A
Heart 2 No N/A
Hindlimb 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Ileum 2 No  (14/127)  (2/2) N/A
Jejunum 2 No  (6/127) N/A
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No  (1/2) N/A
Lower urinary tract 2 No N/A
Lung 2 No  (2/2) N/A
Lymph node 2 No N/A
Mammary gland 2 No  (1/2) N/A
Mesenteric adipose tissue 2 No  (1/2) N/A
Mesenteric lymph node 2 No N/A
Midbrain 2 No  (2/2) N/A
Olfactory lobe 2 No  (1/2) N/A
Ovary 2 No  (1/584)  (1/2) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/584)  (2/2) N/A
Parathyroid gland 2 No N/A
Parotid gland 2 No  (1/2) N/A
Penis 2 No  (1/2) N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (2/2) N/A
Prostate gland 2 No  (12/584)  (1/2) N/A
Quadriceps 2 No  (1/2) N/A
Sciatic nerve 2 No N/A
Skeletal muscle 2 No N/A
Skin 2 No  (2/2) N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No  (2/2) N/A
Spleen 2 No  (2/584)  (2/2) N/A
Stomach 2 No  (12/584)  (2/2) N/A
Stomach pyloric region 2 No N/A
Striatum 2 No N/A
Sublingual gland 2 No  (2/2) N/A
Submandibular gland 2 No  (2/132)  (2/2) N/A
Testis 2 No  (2/584)  (1/2) N/A
Thymus 2 No N/A
Thyroid gland 2 No  (15/584)  (1/2) N/A
Tongue 2 No  (5/127)  (2/2) N/A
Trachea 2 No  (2/2) N/A
Trigeminal V nerve 2 No  (2/2) N/A
Urinary bladder 2 No  (2/2) N/A
Uterus 2 No  (1/2) N/A
Vagina 2 No N/A
Vas deferens 2 No  (15/388)  (1/2) N/A
Vascular system 2 No N/A
Vesicular gland 2 No  (1/2) N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2  (1/51) N/A
Brain 8  (6/485)  (2/8) N/A
Central nervous system ganglion 2  (1/51)  (2/2) N/A
Ear 8  (1/485)  (2/8) N/A
Embryo 8  (1/485)  (2/8) N/A
Eye 8  (1/485)  (2/8) N/A
Foot 8  (1/485)  (2/8) N/A
Forebrain 8  (1/485)  (2/8) N/A
Forelimb 8  (1/485) N/A
Gut 2  (1/50) N/A
Hand 8  (1/485) N/A
Head 8  (5/485) N/A
Heart 8  (1/485) N/A
Hindbrain 8  (6/485)  (2/8) N/A
Hindlimb 8  (1/485)  (2/8) N/A
Liver 8  (1/485)  (2/8) N/A
Lung 8  (1/485) N/A
Mandibular process 8  (1/485) N/A
Maxillary process 8  (1/485) N/A
Midbrain 8  (1/485)  (2/8) N/A
Nose 2  (1/51) N/A
Oral cavity 8  (1/485) N/A
2  (7/25) N/A
Skeleton 2  (1/51)  (2/2) N/A
Skin 8  (1/485) N/A
Spinal cord 2  (1/50)  (2/2) N/A
Tail 8  (1/485) N/A
Tail somite 8  (1/485)  (2/8) N/A
Trachea 2  (1/50) N/A
Urinary system 2  (1/50) N/A

 Associated Images

X-ray: XRay Images Lateral Orientation
20 Images
X-ray: XRay Images Dorso Ventral
40 Images
Embryo LacZ: LacZ images wholemount
24 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Neprotm2a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Neprotm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue
Neprotm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells

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