Gene: Herc1

Name
HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
MGI ID
MGI:2384589
Synonyms
2810449H11Rik D130015N03Rik tbl
View
N/A
Other links
Expression & images (0) Disease models (0) Order (4)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
cataract Herc1em2(IMPC)Wtsi HOM postnatal 6.88×10-08
decreased lean body mass Herc1em3(IMPC)Wtsi HOM postnatal 5.34×10-21
increased leukocyte cell number Herc1em3(IMPC)Wtsi HOM postnatal 3.01×10-08
increased Ly6C low monocyte number Herc1em3(IMPC)Wtsi HOM postnatal 0.00
male infertility Herc1em3(IMPC)Wtsi HOM postpartum stage 0.00
increased mean platelet volume Herc1em3(IMPC)Wtsi HOM postnatal 5.67×10-07
increased monocyte cell number Herc1em3(IMPC)Wtsi HOM postnatal 0.00
decreased bone mineral content Herc1em3(IMPC)Wtsi HOM postnatal 5.91×10-12
decreased blood urea nitrogen level Herc1em2(IMPC)Wtsi HOM postnatal 5.87×10-05
abnormal lens morphology Herc1em2(IMPC)Wtsi HOM postnatal 6.88×10-08
increased total body fat amount Herc1em3(IMPC)Wtsi HOM postnatal 2.56×10-20
decreased bone mineral density Herc1em3(IMPC)Wtsi HOM postnatal 9.00×10-07
increased Ly6C high monocyte number Herc1em3(IMPC)Wtsi HOM postnatal 5.40×10-06
increased eosinophil cell number Herc1em3(IMPC)Wtsi HOM postnatal 5.40×10-06
increased red blood cell distribution width Herc1em3(IMPC)Wtsi HOM postnatal 7.00×10-14
increased B cell number Herc1em3(IMPC)Wtsi HOM postnatal 8.27×10-05
decreased mature B cell number Herc1em3(IMPC)Wtsi HOM postnatal 4.00×10-07

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Viewing: all phenotypes

 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Lateral Orientation
82 Images
X-ray: XRay Images Dorso Ventral
123 Images
X-ray: XRay Images Skull Lateral Orientation
42 Images
X-ray: XRay Images Forepaw
41 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
40 Images
DSS Histology
16 Images
Anti-nuclear antibody assay
10 Images
Eye Morphology: Images Ophthalmoscopy
7 Images
Eye Morphology: Images Slit Lamp
4 Images

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Herc1em1(IMPC)Wtsi Point Mutation Mice
Herc1em2(IMPC)Wtsi Point Mutation Mice
Herc1em3(IMPC)Wtsi Exon Deletion Mice
Herc1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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