Gene: Herc1

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Name
HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
MGI ID
MGI:2384589
Synonyms
2810449H11Rik D130015N03Rik tbl
Embryo viewer
N/A
Other links
Expression & images (0) Disease models (0) Order (4)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased or absent threshold for auditory brainstem response Herc1em3(IMPC)Wtsi HOM Early adult 2.00×10-07
abnormal lens morphology Herc1em2(IMPC)Wtsi HOM Early adult 6.64×10-08
increased monocyte cell number Herc1em3(IMPC)Wtsi HOM Early adult 0.00
decreased bone mineral content Herc1em3(IMPC)Wtsi HOM Early adult 6.91×10-12
increased total body fat amount Herc1em3(IMPC)Wtsi HOM Early adult 1.82×10-20
decreased bone mineral density Herc1em3(IMPC)Wtsi HOM Early adult 1.25×10-06
male infertility Herc1em3(IMPC)Wtsi HOM Early adult 0.00
increased eosinophil cell number Herc1em3(IMPC)Wtsi HOM Early adult 2.00×10-07
increased Ly6C high monocyte number Herc1em3(IMPC)Wtsi HOM Early adult 5.20×10-06
increased Ly6C low monocyte number Herc1em3(IMPC)Wtsi HOM Early adult 0.00
cataract Herc1em2(IMPC)Wtsi HOM Early adult 6.64×10-08
decreased mature B cell number Herc1em3(IMPC)Wtsi HOM Early adult 4.00×10-07
decreased lean body mass Herc1em3(IMPC)Wtsi HOM Early adult 4.64×10-21

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 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Whole Body Dorso Ventral
123 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
40 Images
X-ray: XRay Images Whole Body Lateral Orientation
82 Images
X-ray: XRay Images Forepaw
41 Images
X-ray: XRay Images Skull Lateral Orientation
42 Images
DSS Histology
16 Images
Eye Morphology: Images Ophthalmoscopy
7 Images
Eye Morphology: Images Slit Lamp
4 Images
Anti-nuclear antibody assay
10 Images
Legacy Phenotype Associated Images

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 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Herc1em1(IMPC)Wtsi Point Mutation Mice
Herc1em3(IMPC)Wtsi Exon Deletion Mice
Herc1em2(IMPC)Wtsi Point Mutation Mice
Herc1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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