Not currently registered for phenotyping at IMPC
Phenotyping is currently not planned for a knockout strain of this gene.
Gene Summary
IMPC Data Collections
- No Body Weight Data
- No Embryo Imaging Data
- No Viability Data
Phenotyping is currently not planned for a knockout strain of this gene.
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Ddx60.
There are 2 publications which use IMPC produced mice or data.
Title | Journal | IMPC Allele | PubMed ID |
---|---|---|---|
Mouse superkiller-2-like helicase DDX60 is dispensable for type I IFN induction and immunity to multiple viruses. | European journal of immunology (October 2015) | Ddx60tm1a(EUCOMM)Wtsi Ddx60tm1d(EUCOMM)Wtsi | PMC4833184 |
DDX60 Is Involved in RIG-I-Dependent and Independent Antiviral Responses, and Its Function Is Attenuated by Virus-Induced EGFR Activation. | Cell reports (May 2015) | Ddx60tm1a(EUCOMM)Wtsi Ddx60tm1b(EUCOMM)Wtsi | 25981042 |
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MGI Allele | Allele Type | Produced |
---|---|---|
Ddx60tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | Targeting vectors, ES Cells |
Ddx60tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | ES Cells |
Ddx60em1(IMPC)Ccpcz | Exon Deletion | Mice |
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