Gene: Nae1

Name
NEDD8 activating enzyme E1 subunit 1
MGI ID
MGI:2384561
Synonyms
Appbp1
Viability
Homozygous - Lethal
Other links
View data by physiological system
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
thrombocytopenia Nae1tm1b(EUCOMM)Wtsi HET postnatal 8.82×10-05
preweaning lethality, complete penetrance Nae1tm1b(EUCOMM)Wtsi HOM n/a 0.00

Download data as:  TSV  XLS

Filtered by: all phenotypes

 Expression

IMPC lacZ Expression Data

No Adult expression data was found for this gene.
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 1  (6/485)  (1/1) N/A
Ear 1  (1/485)  (1/1) N/A
Embryo 1  (1/485)  (1/1) N/A
Eye 1  (1/485)  (1/1) N/A
Foot 1  (1/485)  (1/1) N/A
Forebrain 1  (1/485)  (1/1) N/A
Forelimb 1  (1/485)  (1/1) N/A
Hand 1  (1/485)  (1/1) N/A
Head 1  (5/485)  (1/1) N/A
Heart 1  (1/485)  (1/1) N/A
Hindbrain 1  (6/485)  (1/1) N/A
Hindlimb 1  (1/485)  (1/1) N/A
Liver 1  (1/485)  (1/1) N/A
Lung 1  (1/485)  (1/1) N/A
Mandibular process 1  (1/485)  (1/1) N/A
Maxillary process 1  (1/485)  (1/1) N/A
Midbrain 1  (1/485)  (1/1) N/A
Oral cavity 1  (1/485)  (1/1) N/A
Skin 1  (1/485)  (1/1) N/A
Tail 1  (1/485)  (1/1) N/A
Tail somite 1  (1/485)  (1/1) N/A

 Associated Images

X-ray: XRay Images Dorso Ventral
10 Images
X-ray: XRay Images Lateral Orientation
10 Images
Embryo LacZ: LacZ images wholemount
1 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Nae1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Nae1tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice

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