Gene: Il27

Name
interleukin 27
MGI ID
MGI:2384409
Synonyms
IL-27 Il30 IL-27p28 p28
Viability
Homozygous - Viable
Other links
View data by physiological system
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased KLRG1-positive CD4-positive, CD25-positive, alpha-beta regulatory T cell number Il27tm1b(EUCOMM)Wtsi HOM postnatal 0.00
decreased effector memory CD4-positive, alpha-beta T cell number Il27tm1b(EUCOMM)Wtsi HOM postnatal 4.00×10-06
decreased circulating creatinine level Il27tm1b(EUCOMM)Wtsi HOM postnatal 1.58×10-05
decreased mean corpuscular hemoglobin Il27tm1b(EUCOMM)Wtsi HOM postnatal 1.98×10-06
decreased effector memory CD8-positive, alpha-beta T cell number Il27tm1b(EUCOMM)Wtsi HOM postnatal 7.89×10-05

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Filtered by: all phenotypes

 Expression

Expression data not available

 Associated Images

Mesenteric Lymph Node Immunophenotyping: Images associated with FACS analysis
4 Images
DSS Histology
8 Images
Anti-nuclear antibody assay
5 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Il27tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Il27tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Il27tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells

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