Pfkfb3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3

GeneMGI:2181202Synonyms: E330010H22Rik, uPFK-2

Physiological systems

18 / 24 physiological systems tested

1 Significantly impacted by the knock-out

 Skeleton

17 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal bone structure1 supporting datasetPfkfb3tm1b(EUCOMM)WtsiheterozygoteEarly adult1.51x10-5 
decreased bone mineral density1 supporting datasetPfkfb3tm1b(EUCOMM)WtsiheterozygoteEarly adult7.96x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  










* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  

lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Pfkfb3tm1(NCOM)CmhdReporter-tagged deletion allele (with selection cassette)targeting vector
es cell
Pfkfb3tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Pfkfb3tm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Pfkfb3tm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell

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