Gene: Dennd2d

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Name
DENN/MADD domain containing 2D
MGI ID
MGI:2181193
Synonyms
2010308M01Rik
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased prepulse inhibition Dennd2dtm2b(KOMP)Mbp HOM Early adult 9.11×10-06
preweaning lethality, incomplete penetrance Dennd2dtm2b(KOMP)Mbp HOM Early adult 0.00
increased lean body mass Dennd2dtm2b(KOMP)Mbp HOM Early adult 4.23×10-06
thrombocytopenia Dennd2dtm2b(KOMP)Mbp HOM Early adult 1.76×10-05
abnormal behavior Dennd2dtm2b(KOMP)Mbp HET Early adult 8.90×10-06
abnormal bone structure Dennd2dtm2b(KOMP)Mbp HOM Early adult 5.15×10-07
increased bone mineral content Dennd2dtm2b(KOMP)Mbp HOM Early adult 4.36×10-05

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2)  Section images
Aorta 2 No N/A
Bone 2 No  (2/2)  Section images
Brain 2 No  (2/2) N/A
Brainstem 2 No  (2/2) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (2/2)  Section images
Cerebellum 2 No  (2/2)  Section images
Cerebral cortex 2 No  (2/2)  Section images
Epididymis 2 No  (18/134)  (1/2) N/A
Esophagus 2 No  (7/415)  (2/2) N/A
Eye 2 No  (2/2) N/A
Heart 2 No N/A
Hippocampus 2 No  (2/2)  Section images
Hypothalamus 2 No  (2/2) N/A
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584)  (2/2) N/A
Liver 2 No  (2/2)  Section images
Lower urinary tract 2 No N/A
Lung 2 No  (2/2) N/A
Lymph node 2 No  (2/2) N/A
Mammary gland 2 No  (1/2)  Section images
Midbrain 2 No  (2/2) N/A
Olfactory lobe 2 No  (2/2)  Section images
Ovary 2 No  (1/584)  (1/2)  Section images
Oviduct 2 No  (1/2)  Section images
Pancreas 2 No  (5/584)  (2/2)  Section images
Peripheral nervous system 2 No  (2/2) N/A
Peyer's patch 2 No  (2/2)  Section images
Pituitary gland 2 No  (2/2)  Section images
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (2/2) N/A
Small intestine 2 No  (9/584)  (2/2) N/A
Spinal cord 2 No  (2/2) N/A
Spleen 2 No  (2/584)  (2/2) N/A
Stomach 2 No  (12/584)  (2/2) N/A
Striatum 2 No  (2/2) N/A
Submandibular gland 2 No  (2/132)  (2/2) N/A
Testis 2 No  (2/584)  (1/2) N/A
Thalamus 2 No  (2/2)  Section images
Thymus 2 No  (2/2) N/A
Thyroid gland 2 No  (15/584)  (2/2) N/A
Trachea 2 No  (2/2) N/A
Urinary bladder 2 No  (2/2) N/A
Uterus 2 No  (1/2)  Section images
Vascular system 2 No N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No  (2/2) N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/504) N/A
Dorsal root ganglion 2  (1/57) N/A
Ear 2  (1/504) N/A
Embryo 2  (1/505) N/A
Eye 2  (1/504) N/A
Foot 2  (1/504) N/A
Forebrain 2  (1/504) N/A
Forelimb 2  (1/504) N/A
Fronto-nasal process 2  (1/58) N/A
Hand 2  (1/503) N/A
Head 2  (5/504) N/A
Heart 2  (1/504) N/A
Hindbrain 2  (6/504) N/A
Hindlimb 2  (1/503) N/A
Liver 2  (1/504) N/A
Lung 2  (1/500) N/A
Mandibular process 2  (1/504) N/A
Maxillary process 2  (1/504) N/A
Midbrain 2  (1/504) N/A
Nose 2  (1/70) N/A
Oral cavity 2  (1/504) N/A
Skin 2  (1/504) N/A
Spinal cord 2  (1/69) N/A
Tail 2  (1/504) N/A
Tail somite 2  (1/504) N/A

 Associated Images

Original Image
Adult LacZ: LacZ Images Section
16 Images
X-ray: XRay Images Whole Body Lateral Orientation
24 Images
X-ray: XRay Images Forepaw
24 Images
X-ray: XRay Images Skull Lateral Orientation
24 Images
Sleep Wake: Wake state (bmp file)
6 Images
Combined SHIRPA and Dysmorphology
3 Images
X-ray: XRay Images Whole Body Dorso Ventral
24 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
24 Images
Eye Morphology: Images Ophthalmoscopy
24 Images
Electroretinography 2: Rod and cone PDF
6 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Dennd2dtm2b(KOMP)Mbp Reporter-tagged deletion allele (post-Cre) Mice
Dennd2dtm2a(KOMP)Mbp KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Dennd2dtm1a(KOMP)Mbp KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Dennd2dtm41823(L1L2_gt0) Targeting vectors

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