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Genes Phenotypes Help, News, Blog

Gene: Pnma3 MGI:2180565

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Gene Summary

Name:
paraneoplastic antigen MA3
Synonyms:
N/A

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IMPC Data Collections

IMPC Phenotype Summary

Significant
Not Significant
Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

Phenotype System Allele Zyg Sex Life Stage P Value
abnormal blood uric acid level Pnma3em1(IMPC)Rbrc HOM Late adult 1.80×10-05

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Eye Morphology

Images Slit Lamp

2 Images

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X-ray

XRay Images Whole Body Dorso Ventral

10 Images

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X-ray

XRay Images Whole Body Lateral Orientation

10 Images

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Eye Morphology

Images Ophthalmoscopy

4 Images

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Eye Morphology

Images Slit Lamp

1 Images

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Human diseases caused by Pnma3 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Pnma3 by phenotypic similarity.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Hypouricemia, Familial Renal, Due To Tubular Hypersecretion
Hypouricemia OMIM:307830
Lactic Acidosis, Chronic Adult Form
Hyperuricemia OMIM:150170
Hypouricemia, Renal, 2
Hypouricemia OMIM:612076
Hypouricemia, Hypercalcinuria, And Decreased Bone Density
Hypouricemia OMIM:242050
Glomerulocystic kidney disease with hyperuricemia and isosthenuria
Hyperuricemia OMIM:609886
Hyperuricemia, Infantile, With Abnormal Behavior And Normal Hypoxanthine Guanine Phosphoribosyltransferase
Hyperuricemia OMIM:240000
Lesch-Nyhan Phenotype With Normal Hgprt
Hyperuricemia OMIM:308950
Glycogen Storage Disease Due To Muscle Phosphofructokinase Deficiency
Hyperuricemia ORPHA:371
Lesch-Nyhan Syndrome
Hyperuricemia ORPHA:510
Hyperuricemic Nephropathy, Familial Juvenile, 3
Hyperuricemia OMIM:614227
Hyperuricemia, Hprt-Related
Hyperuricemia OMIM:300323
Tubulointerstitial Kidney Disease, Autosomal Dominant, 1
Hyperuricemia OMIM:162000
Cystinuria
Hyperuricemia ORPHA:214
Glycogen Storage Disease Due To Glucose-6-Phosphatase Deficiency
Hyperuricemia ORPHA:364
Tubulointerstitial Kidney Disease, Autosomal Dominant, 4
Hyperuricemia OMIM:613092
Xanthinuria, Type Ii
Hypouricemia OMIM:603592
Glycogen Storage Disease Ixb
Hyperuricemia OMIM:261750
Phosphoribosylpyrophosphate Synthetase Superactivity
Hyperuricemia ORPHA:3222
Glycogen Storage Disease Ixa1
Hyperuricemia OMIM:306000
Glycogen Storage Disease V
Hyperuricemia OMIM:232600
Tubulointerstitial Kidney Disease, Autosomal Dominant, 5
Hyperuricemia OMIM:617056
Mild Phosphoribosylpyrophosphate Synthetase Superactivity
Hyperuricemia ORPHA:411536
Xanthinuria, Type I
Hypouricemia OMIM:278300
Medullary cystic kidney disease 2
Hyperuricemia OMIM:603860
Hypouricemia, Renal, 1
Hypouricemia OMIM:220150
Hypoxanthine Guanine Phosphoribosyltransferase Partial Deficiency
Hyperuricemia ORPHA:79233

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Pnma3

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Pnma3.

No publications found that use IMPC mice or data for Pnma3.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

MGI Allele Allele Type Produced
Pnma3em1(IMPC)Rbrc Intra-exon deletion Mice
Pnma3tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) ES Cells

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