Gene: Casc3

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Phenotype System Allele Zyg Sex Life Stage P Value
abnormal embryo size Casc3tm1.1(KOMP)Vlcg HOM E9.5 0.00
preweaning lethality, incomplete penetrance Casc3tm1.1(KOMP)Vlcg HOM Early adult 0.00
embryonic growth retardation Casc3tm1.1(KOMP)Vlcg HET E9.5 0.00
edema Casc3tm1.1(KOMP)Vlcg HET E9.5 0.00
abnormal pericardium morphology Casc3tm1.1(KOMP)Vlcg HET E9.5 0.00
embryonic lethality prior to tooth bud stage Casc3tm1.1(KOMP)Vlcg HOM E12.5 0.00
embryonic lethality prior to organogenesis Casc3tm1.1(KOMP)Vlcg HOM E9.5 0.00
embryonic growth retardation Casc3tm1.1(KOMP)Vlcg HOM E9.5 0.00
abnormal embryo size Casc3tm1.1(KOMP)Vlcg HET E9.5 0.00

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2)  Section images
Aorta 2 No  (1/2)  Section images
Blood 2 No N/A
Bone marrow 2 No  (2/2)  Section images
Brain 2 No N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No  (2/2)  Section images
Cartilage tissue 2 No N/A
Cecum 2 No  (12/379)  (2/2)  Section images
Cerebellum 2 No  (2/2)  Section images
Cerebral cortex 2 No N/A
Chest bone 2 No N/A
Colon 2 No  (12/127)  (2/2)  Section images
Diaphragm 2 No  (1/2)  Section images
Duodenum 2 No  (2/127)  (2/2)  Section images
Epididymis 2 No  (18/134)  (1/2)  Section images
Esophagus 2 No  (7/415)  (2/2)  Section images
Eye 2 No  (2/2)  Section images
Gall bladder 2 No N/A
Gonadal fat pad 2 No  (1/2)  Section images
Harderian gland 2 No  (2/2)  Section images
Heart 2 No N/A
Hindlimb 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Ileum 2 No  (14/127)  (2/2)  Section images
Jejunum 2 No  (6/127)  (2/2)  Section images
Kidney 2 No  (18/584)  (2/2)  Section images
Large intestine 2 No  (10/584) N/A
Liver 2 No  (2/2)  Section images
Lower urinary tract 2 No N/A
Lung 2 No  (2/2)  Section images
Lymph node 2 No N/A
Mammary gland 2 No  (1/2)  Section images
Mesenteric adipose tissue 2 No  (1/2)  Section images
Mesenteric lymph node 2 No  (2/2)  Section images
Midbrain 2 No  (2/2)  Section images
Olfactory lobe 2 No  (1/2)  Section images
Ovary 2 No  (1/584)  (1/2)  Section images
Oviduct 2 No  (1/2)  Section images
Pancreas 2 No  (5/584)  (2/2)  Section images
Parathyroid gland 2 No  (1/2)  Section images
Parotid gland 2 No  (2/2)  Section images
Penis 2 No  (1/2)  Section images
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (2/2)  Section images
Prostate gland 2 No  (12/584)  (1/2)  Section images
Quadriceps 2 No  (2/2)  Section images
Sciatic nerve 2 No  (1/2)  Section images
Skeletal muscle 2 No N/A
Skin 2 No  (2/2)  Section images
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No  (2/2)  Section images
Spleen 2 No  (2/584)  (2/2)  Section images
Stomach 2 No  (12/584)  (2/2)  Section images
Stomach pyloric region 2 No N/A
Striatum 2 No N/A
Sublingual gland 2 No  (2/2)  Section images
Submandibular gland 2 No  (2/132)  (2/2)  Section images
Testis 2 No  (2/584)  (1/2)  Section images
Thymus 2 No  (2/2)  Section images
Thyroid gland 2 No  (15/584)  (2/2)  Section images
Tongue 2 No  (5/127)  (2/2)  Section images
Trachea 2 No  (2/2)  Section images
Trigeminal V nerve 2 No  (2/2)  Section images
Urinary bladder 2 No  (2/2)  Section images
Uterus 2 No  (1/2)  Section images
Vagina 2 No  (1/2)  Section images
Vas deferens 2 No  (15/388)  (1/2)  Section images
Vascular system 2 No N/A
Vesicular gland 2 No  (1/2)  Section images
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2  (1/61)  (2/2) N/A
Brain 6  (6/504)  (2/6) N/A
Central nervous system ganglion 2  (1/70)  (2/2) N/A
Ear 6  (1/504)  (2/6) N/A
Embryo 6  (1/505)  (2/6) N/A
Eye 6  (1/504)  (2/6) N/A
Foot 6  (1/504)  (2/6) N/A
Forebrain 6  (1/504)  (2/6) N/A
Forelimb 6  (1/504) N/A
Gut 2  (1/56)  (2/2) N/A
Hand 6  (1/503) N/A
Head 6  (5/504)  (2/6) N/A
Heart 6  (1/504)  (2/6) N/A
Hindbrain 6  (6/504) N/A
Hindlimb 6  (1/503)  (2/6) N/A
Liver 6  (1/504)  (2/6) N/A
Lung 6  (1/500)  (2/6) N/A
Mandibular process 6  (1/504) N/A
Maxillary process 6  (1/504) N/A
Midbrain 6  (1/504)  (2/6) N/A
Nose 2  (1/70) N/A
Oral cavity 6  (1/504) N/A
2  (7/37)  (2/2) N/A
Skeleton 2  (1/70)  (2/2) N/A
Skin 6  (1/504)  (2/6) N/A
Spinal cord 2  (1/69) N/A
Tail 6  (1/504)  (2/6) N/A
Tail somite 6  (1/504)  (2/6) N/A
Trachea 2  (1/56) N/A
Urinary system 2  (1/56)  (2/2) N/A

 Associated Images

Gross Morphology Embryo E9.5
6 Images
Embryo LacZ: LacZ images wholemount
24 Images
Adult LacZ: LacZ Images Section
169 Images
X-ray: XRay Images Whole Body Lateral Orientation
19 Images
X-ray: XRay Images Whole Body Dorso Ventral
33 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Casc3tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Casc3tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue

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