Genes Phenotypes

Gene: Rhbdl3

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Name
rhomboid like 3
MGI ID
MGI:2179276
Synonyms
Rhbdl4 Vrho Ventrhoid
Viability
Homozygous - Subviable
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (3) Measurements chart (321) All data table (840)
Expression & images (67) Disease models (0) Order (4)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
preweaning lethality, incomplete penetrance Rhbdl3tm1b(EUCOMM)Wtsi HOM Early adult 0.00
tremors Rhbdl3tm1b(EUCOMM)Wtsi HET Early adult 7.53×10-05
abnormal behavior Rhbdl3tm1b(EUCOMM)Wtsi HET Early adult 2.17×10-05

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Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 4 No  (2/584) N/A
Aorta 4 No N/A
Bone 4 No N/A
Brain 4 No  (3/4)  Wholemount images
Brainstem 4 No  (2/4)  Wholemount images
Brown adipose tissue 4 No N/A
Cartilage tissue 4 No N/A
Cerebellum 4 No  (3/4)  Wholemount images
Cerebral cortex 4 No  (3/4)  Wholemount images
Esophagus 4 No  (7/415) N/A
Eye 4 No N/A
Gall bladder 4 No N/A
Heart 4 No  (4/4)  Wholemount images
Hippocampus 4 No  (3/4)  Wholemount images
Hypothalamus 4 No  (2/4)  Wholemount images
Kidney 4 No  (18/584) N/A
Large intestine 4 No  (10/584) N/A
Liver 4 No N/A
Lower urinary tract 4 No N/A
Lung 4 No  (4/4)  Wholemount images
Lymph node 4 No  (3/4)  Wholemount images
Mammary gland 4 No N/A
Olfactory lobe 4 No  (2/4)  Wholemount images
Oral epithelium 4 No N/A
Ovary 4 No  (1/584) N/A
Oviduct 4 No  Wholemount images
Pancreas 4 No  (5/584) N/A
Parathyroid gland 4 No N/A
Peripheral nervous system 4 No  (4/4)  Wholemount images
Peyer's patch 4 No N/A
Pituitary gland 4 No N/A
Prostate gland 4 No  (12/584) N/A
Skeletal muscle 4 No N/A
Skin 4 No  (4/4)  Wholemount images
Small intestine 4 No  (9/584) N/A
Spinal cord 4 No  (4/4)  Wholemount images
Spleen 4 No  (2/584) N/A
Stomach 4 No  (12/584) N/A
Striatum 4 No  (2/4)  Wholemount images
Testis 4 No  (2/584)  (2/4)  Wholemount images
Thymus 4 No  (4/4)  Wholemount images
Thyroid gland 4 No  (15/584) N/A
Trachea 4 No N/A
Uterus 4 No  (2/4)  Wholemount images
Vascular system 4 No N/A
White adipose tissue 4 No  (1/4) N/A
LacZ Wholemount Images
cardiovascular system (1)
Heart expression
MA:0000072
immune system (2)
Lymph Node tissue not available
MA:0000139
integumental system (1)
Skin expression
MA:0000151
nervous system (5)
Brain expression
Cerebral Cortex expression
Hippocampus expression
Striatum no expression
MA:0000168
MA:0000185
MA:0000191
MA:0000891
postnatal mouse (12)
Brain expression
Cerebral Cortex expression
Hippocampus expression
Striatum no expression
MA:0000168
MA:0000185
MA:0000191
MA:0000891
reproductive system (2)
Oviduct ambiguous
Uterus expression
MA:0000385
MA:0000389
respiratory system (1)
Lung expression
MA:0000415
trunk (6)
Heart expression
MA:0000072
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/504)  (4/4) N/A
Ear 2  (1/504) N/A
Embryo 2  (1/505)  (4/4) N/A
Eye 2  (1/504)  (1/4) N/A
Foot 2  (1/504) N/A
Forebrain 2  (1/504)  (3/4) N/A
Forelimb 2  (1/504)  (3/4) N/A
Hand 2  (1/503) N/A
Head 2  (5/504)  (4/4) N/A
Heart 2  (1/504) N/A
Hindbrain 2  (6/504)  (4/4) N/A
Hindlimb 2  (1/503)  (2/4) N/A
Liver 2  (1/504) N/A
Lung 2  (1/500) N/A
Mandibular process 2  (1/504) N/A
Maxillary process 2  (1/504) N/A
Midbrain 2  (1/504)  (4/4) N/A
Oral cavity 2  (1/504) N/A
Skin 2  (1/504)  (2/4) N/A
Tail 2  (1/504)  (4/4) N/A
Tail somite 2  (1/504) N/A

 Associated Images

Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
9 Images
Adult LacZ: LacZ Images Wholemount
12 Images
Embryo LacZ: LacZ images wholemount
8 Images
Echo: M-Mode Images
68 Images
X-ray: XRay Images Whole Body Dorso Ventral
13 Images
X-ray: XRay Images Whole Body Lateral Orientation
13 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
13 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Rhbdl3tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Rhbdl3tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Rhbdl3tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Rhbdl3tm47173(L1L2_gt0) Targeting vectors

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