Genes Phenotypes

Gene: Dicer1

Name
dicer 1, ribonuclease type III
MGI ID
MGI:2177178
Synonyms
Dicer1 D12Ertd7e 1110006F08Rik
Viability
Homozygous - Lethal
Other links
MGI   Ensembl  
Significant phenotypes (5) All measurements (235) Expression & images (67) Disease models (0) Order (3)
View data by physiological system
Significant
Not Significant
Not tested
Body weight
Phenotype System Allele Zyg Sex Life Stage P Value
decreased neutrophil cell number Dicer1tm1b(EUCOMM)Wtsi HET postnatal 1.11×10-06
embryonic lethality prior to organogenesis Dicer1tm1b(EUCOMM)Wtsi HOM embryonic day 9.5 0.00
decreased spleen weight Dicer1tm1b(EUCOMM)Wtsi HET postnatal 4.75×10-07
decreased red blood cell distribution width Dicer1tm1b(EUCOMM)Wtsi HET postnatal 1.68×10-08
preweaning lethality, complete penetrance Dicer1tm1b(EUCOMM)Wtsi HOM n/a 0.00

Download data as:  TSV  XLS

Filtered by: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2)  Wholemount images
Aorta 2 No  (2/2)  Wholemount images
Bone 2 No N/A
Brain 2 No  (2/2)  Wholemount images
Brainstem 2 No  (2/2)  Wholemount images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (2/2)  Wholemount images
Cerebellum 2 No  (2/2)  Wholemount images
Cerebral cortex 2 No  (2/2)  Wholemount images
Esophagus 2 No  (7/415)  (2/2)  Wholemount images
Eye 2 No  (2/2)  Wholemount images
Gall bladder 2 No  (2/2)  Wholemount images
Heart 2 No  (2/2)  Wholemount images
Hippocampus 2 No  (2/2)  Wholemount images
Hypothalamus 2 No  (2/2)  Wholemount images
Kidney 2 No  (18/584)  (2/2)  Wholemount images
Large intestine 2 No  (10/584)  (2/2)  Wholemount images
Liver 2 No N/A
Lower urinary tract 2 No  (2/2)  Wholemount images
Lung 2 No  (2/2)  Wholemount images
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/2)  Wholemount images
Oral epithelium 2 No N/A
Ovary 2 No  (1/584)  (1/2)  Wholemount images
Oviduct 2 No  (1/2)  Wholemount images
Pancreas 2 No  (5/584)  (2/2)  Wholemount images
Parathyroid gland 2 No  (2/2)  Wholemount images
Peripheral nervous system 2 No  (2/2)  Wholemount images
Peyer's patch 2 No N/A
Pituitary gland 2 No  (2/2)  Wholemount images
Prostate gland 2 No  (12/584)  (1/2)  Wholemount images
Skeletal muscle 2 No N/A
Skin 2 No  (2/2)  Wholemount images
Small intestine 2 No  (9/584)  (2/2)  Wholemount images
Spinal cord 2 No  (2/2)  Wholemount images
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584)  (2/2)  Wholemount images
Striatum 2 No  (2/2)  Wholemount images
Testis 2 No  (2/584)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584)  (2/2)  Wholemount images
Trachea 2 No  (2/2)  Wholemount images
Uterus 2 No  (1/2)  Wholemount images
Vascular system 2 No  (2/2)  Wholemount images
White adipose tissue 2 No N/A
LacZ Wholemount Images
cardiovascular system (3)
Aorta expression
Heart expression
MA:0000062
MA:0000072
digestive system (4)
Gall Bladder expression
MA:0000356
endocrine system (2)
Adrenal gland expression
MA:0000116
exocrine system (1)
Lower Urinary Tract expression
Prostate gland expression
MA:0002636
MA:0000404
integumental system (1)
Skin expression
MA:0000151
nervous system (5)
Cerebral Cortex expression
Striatum expression
Hypothalamus expression
Brain expression
MA:0000185
MA:0000891
MA:0000173
MA:0000168
postnatal mouse (22)
Adrenal gland expression
MA:0000116
reproductive system (3)
Lower Urinary Tract expression
Prostate gland expression
MA:0002636
MA:0000404
respiratory system (2)
Lung expression
MA:0000415
sensory organ (1)
Eye expression
MA:0000261
set of connective tissues (2)
Cartilage tissue expression
Vascular System expression
MA:0000104
MA:0002718
trunk (14)
Adrenal gland expression
MA:0000116
urinary system (2)
Kidney expression
MA:0000368
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/485)  (2/2) N/A
Ear 2  (1/485)  (1/2) N/A
Embryo 2  (1/485)  (2/2) N/A
Eye 2  (1/485)  (2/2) N/A
Foot 2  (1/485)  (1/2) N/A
Forebrain 2  (1/485)  (2/2) N/A
Forelimb 2  (1/485)  (2/2) N/A
Hand 2  (1/485)  (1/2) N/A
Head 2  (5/485)  (2/2) N/A
Heart 2  (1/485)  (1/2) N/A
Hindbrain 2  (6/485)  (2/2) N/A
Hindlimb 2  (1/485)  (2/2) N/A
Liver 2  (1/485)  (1/2) N/A
Lung 2  (1/485)  (1/2) N/A
Mandibular process 2  (1/485)  (1/2) N/A
Maxillary process 2  (1/485)  (1/2) N/A
Midbrain 2  (1/485)  (2/2) N/A
Oral cavity 2  (1/485)  (1/2) N/A
Skin 2  (1/485)  (1/2) N/A
Tail 2  (1/485)  (2/2) N/A
Tail somite 2  (1/485)  (1/2) N/A

 Associated Images

Echo: M-Mode Images
32 Images
X-ray: XRay Images Lateral Orientation
10 Images
X-ray: XRay Images Dorso Ventral
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
9 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images
Embryo LacZ: LacZ images wholemount
4 Images
Adult LacZ: LacZ Images Wholemount
22 Images

 Disease Models

Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Dicer1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Dicer1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Dicer1tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice

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