Gene: Vps37d

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Phenotype System Allele Zyg Sex Life Stage P Value
abnormal retinal inner nuclear layer morphology Vps37dtm2b(EUCOMM)Wtsi HET postnatal 2.40×10-08
hypoactivity Vps37dtm2b(EUCOMM)Wtsi HET postnatal 2.19×10-06
abnormal body wall morphology Vps37dtm2b(EUCOMM)Wtsi HOM embryonic day 18.5 0.00
abnormal behavior Vps37dtm2b(EUCOMM)Wtsi HET postnatal 4.15×10-08
preweaning lethality, complete penetrance Vps37dtm2b(EUCOMM)Wtsi HOM n/a 0.00
decreased total retina thickness Vps37dtm2b(EUCOMM)Wtsi HET postnatal 3.83×10-12
increased heart rate variability Vps37dtm2b(EUCOMM)Wtsi HET postnatal 5.09×10-05

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Bone 2 No N/A
Brain 2 No  (2/2)  Wholemount images
Brainstem 2 No  (2/2)  Wholemount images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (2/2)  Wholemount images
Cecum 2 No  (12/383) N/A
Cerebellum 2 No  (2/2)  Wholemount images
Cerebral cortex 2 No  (2/2)  Wholemount images
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No N/A
Hippocampus 2 No  (2/2)  Wholemount images
Hypothalamus 2 No  (2/2)  Wholemount images
Kidney 2 No  (18/584) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/2)  Wholemount images
Oral epithelium 2 No N/A
Ovary 2 No  (1/584)  (1/2) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No  (2/2)  Wholemount images
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No  (2/2)  Wholemount images
Testis 2 No  (2/584)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No  (2/2)  Wholemount images
Trigeminal V nerve 2 No N/A
Uterus 2 No N/A
Vas deferens 2 No  (15/388)  Wholemount images
Vascular system 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Heart atrium 3  (1/47) N/A
Axial skeleton 3  (1/51) N/A
Brain 3  (6/485) N/A
Central nervous system ganglion 3  (1/51) N/A
Cranium 3  (1/46) N/A
Dorsal root ganglion 3  (1/47) N/A
Ear 3  (1/485) N/A
Embryo 3  (1/485)  (2/3) N/A
Outer ear 3  (1/47) N/A
Eye 3  (1/485) N/A
Femur pre-cartilage condensation 3  (1/46) N/A
Foot 3  (1/485) N/A
Forearm 3  (1/282) N/A
Forebrain 3  (1/485) N/A
Forelimb 3  (1/485) N/A
Fronto-nasal process 3  (1/48) N/A
Gut 3  (1/50) N/A
Hand 3  (1/485) N/A
Head 3  (5/485)  (2/3) N/A
Head mesenchyme 3  (1/47)  (2/3) N/A
Heart 3  (1/485) N/A
Heart ventricle 3  (1/47) N/A
Hindbrain 3  (6/485) N/A
Hindlimb 3  (1/485) N/A
Humerus pre-cartilage condensation 3  (1/46) N/A
Inner ear 3  (1/46) N/A
Intestine 3  (1/47) N/A
Liver 3  (1/485) N/A
Lower leg 3  (1/282) N/A
Lung 3  (1/485) N/A
Mandibular process 3  (1/485)  (1/3) N/A
Maxillary process 3  (1/485)  (2/3) N/A
Mesonephros of female 3  (1/46) N/A
Mesonephros of male 3  (1/46) N/A
Metanephros 3  (1/46) N/A
Midbrain 3  (1/485) N/A
Nasal septum 3  (1/47)  (2/3) N/A
Nose 3  (1/51)  (2/3) N/A
Notochord 3  (1/47) N/A
Oral cavity 3  (1/485) N/A
Outflow tract 3  (1/47) N/A
Pancreas 3  (1/46) N/A
Pericardium 3  (1/46) N/A
Pharynx 3  (1/46) N/A
Radius-ulna pre-cartilage condensation 3  (1/46) N/A
Rib pre-cartilage condensation 3  (1/46) N/A
Skeleton 3  (1/51) N/A
Skin 3  (1/485) N/A
Spinal cord 3  (1/50) N/A
Stomach 3  (1/46) N/A
Tail 3  (1/485) N/A
Tail somite 3  (1/485) N/A
Thoracic vertebral cartilage condensation 3  (1/46) N/A
Tongue 3  (1/46) N/A
Trachea 3  (1/50) N/A
Trunk mesenchyme 3  (1/47) N/A
Umbilical artery embryonic part 3  (1/47) N/A
Umbilical vein embryonic part 3  (1/47) N/A
Upper arm 3  (1/282) N/A
Upper leg 3  (1/282) N/A
Urinary system 3  (1/50) N/A
Vibrissa 3  (1/47) N/A

 Associated Images

X-ray: XRay Images Skull Dorso Ventral Orientation
4 Images
X-ray: XRay Images Lateral Orientation
4 Images
Adult LacZ: LacZ Images Wholemount
7 Images
X-ray: XRay Images Forepaw
4 Images
X-ray: XRay Images Dorso Ventral
4 Images
X-ray: XRay Images Skull Lateral Orientation
4 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Femur - developmental and structural abnormality Vps37dtm2b(EUCOMM)Wtsi HET postnatal

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Vps37dtm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Vps37dtm2a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Vps37dtm2b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue

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