Gene: Tiparp

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Name
TCDD-inducible poly(ADP-ribose) polymerase
MGI ID
MGI:2159210
Synonyms
PARP-7 PARP7 DDF1
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
enlarged heart Tiparptm1b(EUCOMM)Wtsi HET Early adult 0.00
abnormal seminal vesicle morphology Tiparptm1b(EUCOMM)Wtsi HOM Early adult 0.00
abnormal spleen morphology Tiparptm1b(EUCOMM)Wtsi HOM Early adult 0.00
preweaning lethality, incomplete penetrance Tiparptm1b(EUCOMM)Wtsi HOM Early adult 0.00
decreased lymphocyte cell number Tiparptm1b(EUCOMM)Wtsi HET Early adult 1.61×10-06
hydrometra Tiparptm1b(EUCOMM)Wtsi HOM Early adult 0.00
small superior vagus ganglion Tiparptm1b(EUCOMM)Wtsi HET Early adult 0.00
scaly skin Tiparptm1b(EUCOMM)Wtsi HET Early adult 0.00
abnormal heart morphology Tiparptm1b(EUCOMM)Wtsi HET Early adult 0.00
enlarged spleen Tiparptm1b(EUCOMM)Wtsi HOM Early adult 0.00
abnormal skin morphology Tiparptm1b(EUCOMM)Wtsi HET Early adult 0.00
hydrometra Tiparptm1b(EUCOMM)Wtsi HET Early adult 0.00
small superior vagus ganglion Tiparptm1b(EUCOMM)Wtsi HOM Early adult 0.00

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Blood 2 No N/A
Bone marrow 2 No N/A
Brain 2 No N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cecum 2 No  (12/379) N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Chest bone 2 No N/A
Colon 2 No  (12/127) N/A
Diaphragm 2 No N/A
Duodenum 2 No  (2/127) N/A
Epididymis 2 No  (18/134)  (1/2)  Section images
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Gonadal fat pad 2 No N/A
Harderian gland 2 No N/A
Heart 2 No N/A
Hindlimb 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Ileum 2 No  (14/127) N/A
Jejunum 2 No  (6/127) N/A
Kidney 2 No  (18/584) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Mesenteric adipose tissue 2 No N/A
Mesenteric lymph node 2 No N/A
Midbrain 2 No N/A
Olfactory lobe 2 No N/A
Ovary 2 No  (1/584)  (1/2)  Section images
Oviduct 2 No  (1/2)  Section images
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No N/A
Parotid gland 2 No N/A
Penis 2 No  (1/2)  Section images
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584) N/A
Quadriceps 2 No N/A
Sciatic nerve 2 No N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Stomach pyloric region 2 No N/A
Striatum 2 No N/A
Sublingual gland 2 No N/A
Submandibular gland 2 No  (2/132) N/A
Testis 2 No  (2/584)  (1/2)  Section images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Tongue 2 No  (5/127)  (1/2)  Section images
Trachea 2 No N/A
Trigeminal V nerve 2 No N/A
Urinary bladder 2 No  (1/2)  Section images
Uterus 2 No  (1/2)  Section images
Vagina 2 No  (1/2)  Section images
Vas deferens 2 No  (15/388)  (1/2)  Section images
Vascular system 2 No N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
No Embryo expression data was found for this gene.

 Associated Images

X-ray: XRay Images Whole Body Lateral Orientation
10 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
Adult LacZ: LacZ Images Section
14 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Tiparptm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Tiparptm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue

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