Gene: Dppa1

Log in to follow

Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
embryonic lethality prior to organogenesis Dppa1tm1b(KOMP)Wtsi HOM E9.5 0.00
abnormal spleen morphology Dppa1tm1b(KOMP)Wtsi HET Early adult 0.00
abnormal pericardium morphology Dppa1tm1b(KOMP)Wtsi HET E9.5 0.00
abnormal embryo size Dppa1tm1b(KOMP)Wtsi HET E9.5 0.00
increased heart weight Dppa1tm1a(KOMP)Wtsi HOM Early adult 4.30×10-05
abnormal embryo turning Dppa1tm1b(KOMP)Wtsi HET E9.5 0.00
preweaning lethality, complete penetrance Dppa1tm1b(KOMP)Wtsi HOM Early adult 0.00
increased bone mineral density Dppa1tm1a(KOMP)Wtsi HOM Early adult 7.93×10-07

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2)  Wholemount images
Aorta 2 No  (2/2)  Wholemount images
Bone 2 No  (2/2)  Wholemount images
Brain 2 No  (2/2)  Wholemount images
Brainstem 2 No  (2/2)  Wholemount images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (2/2)  Wholemount images
Cecum 1 No  (12/379) N/A
Cerebellum 2 No  (2/2)  Wholemount images
Cerebral cortex 2 No  (2/2)  Wholemount images
Esophagus 2 No  (7/415)  (2/2)  Wholemount images
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (2/2)  Wholemount images
Hippocampus 2 No  (2/2)  Wholemount images
Hypothalamus 2 No  Wholemount images
Kidney 2 No  (18/584)  (2/2)  Wholemount images
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (2/2)  Wholemount images
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Mesenteric lymph node 2 No N/A
Olfactory lobe 2 No  (2/2)  Wholemount images
Oral epithelium 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/584)  (2/2)  Wholemount images
Parathyroid gland 2 No  (2/2) N/A
Peripheral nervous system 2 No  (2/2)  Wholemount images
Peyer's patch 2 No N/A
Pituitary gland 2 No  (2/2)  Wholemount images
Prostate gland 2 No  (12/584)  (1/2)  Wholemount images
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No  (2/2)  Wholemount images
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No  (2/2)  Wholemount images
Testis 2 No  (2/584)  (1/2)  Wholemount images
Thymus 2 No  (2/2) N/A
Thyroid gland 2 No  (15/584)  (2/2) N/A
Trachea 2 No  (2/2) N/A
Trigeminal V nerve 2 No  (2/2)  Wholemount images
Urinary bladder 2 No  (2/2) N/A
Uterus 2 No  (1/2) N/A
Vas deferens 2 No  (15/388)  Wholemount images
Vascular system 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Heart atrium 2  (1/57)  (2/2) N/A
Axial skeleton 2  (1/61)  (2/2) N/A
Brain 2  (6/504)  (2/2) N/A
Central nervous system ganglion 2  (1/70)  (2/2) N/A
Cranium 2  (1/61)  (2/2) N/A
Dorsal root ganglion 2  (1/57)  (2/2) N/A
Ear 2  (1/504)  (2/2) N/A
Embryo 2  (1/505)  (2/2) N/A
Outer ear 2  (1/66)  (2/2) N/A
Eye 2  (1/504)  (2/2) N/A
Femur pre-cartilage condensation 2  (1/52)  (2/2) N/A
Foot 2  (1/504)  (2/2) N/A
Forearm 2  (1/297)  (2/2) N/A
Forebrain 2  (1/504)  (2/2) N/A
Forelimb 2  (1/504)  (2/2) N/A
Fronto-nasal process 2  (1/58)  (2/2) N/A
Gut 2  (1/56)  (2/2) N/A
Hand 2  (1/503)  (2/2) N/A
Head 2  (5/504)  (2/2) N/A
Head mesenchyme 2  (1/57)  (2/2) N/A
Heart 2  (1/504)  (2/2) N/A
Heart ventricle 2  (1/57)  (2/2) N/A
Hindbrain 2  (6/504)  (2/2) N/A
Hindlimb 2  (1/503)  (2/2) N/A
Humerus pre-cartilage condensation 2  (1/61)  (2/2) N/A
Inner ear 2  (1/61)  (2/2) N/A
Intestine 2  (1/55)  (2/2) N/A
Liver 2  (1/504)  (2/2) N/A
Lower leg 2  (1/297)  (2/2) N/A
Lung 2  (1/500)  (2/2) N/A
Mandibular process 2  (1/504)  (2/2) N/A
Maxillary process 2  (1/504)  (2/2) N/A
Mesonephros of female 2  (1/52)  (1/2) N/A
Mesonephros of male 2  (1/52)  (1/2) N/A
Metanephros 2  (1/52)  (2/2) N/A
Midbrain 2  (1/504)  (2/2) N/A
Nasal septum 2  (1/57)  (2/2) N/A
Nose 2  (1/70)  (2/2) N/A
Notochord 2  (1/57)  (2/2) N/A
Oral cavity 2  (1/504)  (2/2) N/A
Outflow tract 2  (1/57)  (2/2) N/A
Pancreas 2  (1/52)  (2/2) N/A
Pericardium 2  (1/52)  (2/2) N/A
Pharynx 2  (1/52)  (2/2) N/A
Radius-ulna pre-cartilage condensation 2  (1/61)  (2/2) N/A
Rib pre-cartilage condensation 2  (1/54)  (2/2) N/A
Skeleton 2  (1/70)  (2/2) N/A
Skin 2  (1/504)  (2/2) N/A
Spinal cord 2  (1/69)  (2/2) N/A
Stomach 2  (1/52)  (2/2) N/A
Tail 2  (1/504)  (2/2) N/A
Tail somite 2  (1/504)  (2/2) N/A
Thoracic vertebral cartilage condensation 2  (1/52)  (2/2) N/A
Tongue 2  (1/52)  (2/2) N/A
Trachea 2  (1/56)  (2/2) N/A
Trunk mesenchyme 2  (1/57)  (2/2) N/A
Umbilical artery embryonic part 2  (1/57)  (2/2) N/A
Umbilical vein embryonic part 2  (1/57)  (2/2) N/A
Upper arm 2  (1/297)  (2/2) N/A
Upper leg 2  (1/297)  (2/2) N/A
Urinary system 2  (1/56)  (2/2) N/A
Vibrissa 2  (1/66)  (2/2) N/A

 Associated Images

Adult LacZ: LacZ Images Wholemount
13 Images
X-ray: XRay Images Whole Body Lateral Orientation
36 Images
X-ray: XRay Images Whole Body Dorso Ventral
56 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
25 Images
X-ray: XRay Images Skull Lateral Orientation
23 Images
X-ray: XRay Images Forepaw
25 Images
Legacy Phenotype Associated Images

View all 74 images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

This service may be affected by the Covid-19 pandemic. See how

MGI Allele Allele Type Produced
Dppa1tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Dppa1tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Dppa1tm37733(L1L2_st1) Targeting vectors

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter