Snip1 | Smad nuclear interacting protein 1

GeneMGI:2156003Synonyms: 2410133M08Rik

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Vision/eye Behavior/neurological Mortality/aging

16 No significant impact

4 Not tested

Data collections

Viability data
Body weight measurements
Embryo imaging data
Gene metrics:5Significant phenotypes
1Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues

Phenotypes

abnormal tail movements1 supporting datasetSnip1tm1a(EUCOMM)WtsiheterozygoteEarly adult7.93x10-6 
abnormal placement of pupils1 supporting datasetSnip1tm1a(EUCOMM)WtsiheterozygoteEarly adult1.54x10-5 
preweaning lethality, complete penetrance2 supporting datasetsSnip1tm1a(EUCOMM)WtsihomozygoteEarly adultN/A * 
decreased circulating total protein level1 supporting datasetSnip1tm1a(EUCOMM)WtsiheterozygoteEarly adult7.29x10-8 
decreased circulating iron level1 supporting datasetSnip1tm1a(EUCOMM)WtsiheterozygoteEarly adult2.66x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

adrenal glandheterozygoten/a100% (2/2)0.7% (4/570)
aortaheterozygoten/an/a0.19% (1/533)
blood vesselheterozygoten/a0% (0/2)0% (0/173)
boneheterozygoten/a100% (2/2)0% (0/394)
brainheterozygoten/a100% (2/2)0.86% (5/579)
brainstemheterozygoten/an/a0.41% (2/490)
brown adipose tissueheterozygoten/a0% (0/2)0% (0/588)
cartilage tissueheterozygoten/a100% (2/2)0.22% (1/454)
cerebellumheterozygoten/an/a0.56% (3/532)
cerebral cortexheterozygoten/an/a0.41% (2/491)
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Associated images

Histopathology

IMPC related publications

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Snip1tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Snip1tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Snip1tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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