Gene: Sec63

Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
preweaning lethality, complete penetrance Sec63tm1b(EUCOMM)Hmgu HOM n/a 0.00
embryonic lethality prior to tooth bud stage Sec63tm1b(EUCOMM)Hmgu HOM embryonic day 12.5 0.00
impaired glucose tolerance Sec63tm1b(EUCOMM)Hmgu HET postnatal 5.63×10-05
absent vibrissae Sec63tm1b(EUCOMM)Hmgu HET postnatal 9.67×10-07
improved glucose tolerance Sec63tm1b(EUCOMM)Hmgu HET postnatal 5.63×10-05
embryonic lethality prior to organogenesis Sec63tm1b(EUCOMM)Hmgu HOM embryonic day 9.5 0.00
abnormal vibrissa morphology Sec63tm1b(EUCOMM)Hmgu HET postnatal 1.11×10-07

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2) N/A
Aorta 2 No N/A
Bone 2 No N/A
Brain 2 No  (2/2) N/A
Brainstem 2 No  (2/2) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No  (1/2) N/A
Cerebral cortex 2 No  (2/2) N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (2/2) N/A
Hippocampus 2 No  (2/2) N/A
Hypothalamus 2 No  (2/2) N/A
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (2/2) N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/2) N/A
Oral epithelium 2 No N/A
Ovary 2 No  (1/584)  (1/2) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/584)  (2/2) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/2) N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No  (2/2) N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No N/A
Testis 2 No  (2/584)  (1/2) N/A
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Uterus 2 No  (1/2) N/A
Vascular system 2 No  (2/2) N/A
White adipose tissue 2 No N/A
No Embryo expression data was found for this gene.

 Associated Images

Phenotype associated images not available

 Disease Models

Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Sec63tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Sec63tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice, Tissue

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter