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Gene: Muc4 MGI:2153525

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Not currently registered for phenotyping at IMPC

Phenotyping is currently not planned for a knockout strain of this gene.

Gene Summary

Name:
mucin 4
Synonyms:
4933405I11Rik

Order Alleles

IMPC Data Collections

  • No Body Weight Data
  • No Embryo Imaging Data
  • No Viability Data

IMPC Phenotype Summary

Significant
Not Significant
Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Muc4 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Muc4 by phenotypic similarity.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Human Coronavirus Sensitivity
Susceptibility to coronavirus 229e OMIM:122460
Leishmaniasis, Tegumentary, Susceptibility To
Tegumentary leishmaniasis susceptibility OMIM:602068
Varicella, Severe Recurrent
Severe recurrent varicella OMIM:600670
Coxsackievirus B3 Susceptibility
Recurrent viral infections OMIM:120050
Ciliary Discoordination Due To Random Ciliary Orientation
Recurrent infections OMIM:215518
Immunodeficiency 30
Recurrent mycobacterial infections, Recurrent infections OMIM:614891
Microcephaly-Polymicrogyria-Corpus Callosum Agenesis Syndrome
Respiratory distress, Recurrent infections ORPHA:171703
Pulmonary Blastoma
Dyspnea, Recurrent pneumonia, Weight loss ORPHA:64741
Immunodeficiency 95
Respiratory distress, Recurrent respiratory infections, Recurrent viral upper respiratory tract i... OMIM:619773
Neutrophil Actin Dysfunction
Recurrent bacterial infections OMIM:257150
Emphysema, Congenital Lobar
Respiratory distress OMIM:130710
Hypomyelination Neuropathy-Arthrogryposis Syndrome
Respiratory distress ORPHA:2680
Bardet-Biedl Syndrome 16
Bronchiolitis, Respiratory distress, Recurrent otitis media, Obesity, Recurrent respiratory infec... OMIM:615993
Isolated Congenital Hypoglossia/Aglossia
Respiratory distress, Dyspnea, Weight loss ORPHA:141152
Interstitial Pneumonitis, Desquamative, Familial
Respiratory distress, Tachypnea, Recurrent upper respiratory tract infections, Failure to thrive OMIM:263000
Ciliary Dyskinesia, Primary, 47, And Lissencephaly
Respiratory distress, Recurrent respiratory infections OMIM:619466
Gaucher Disease Type 2
Respiratory distress, Recurrent respiratory infections, Abnormal pattern of respiration ORPHA:77260
Succinic Acidemia
Respiratory distress OMIM:600335
Growth Hormone Insensitivity Syndrome With Immune Dysregulation 1, Autosomal Recessive
Respiratory distress, Failure to thrive OMIM:245590
Pulmonary Non-Tuberculous Mycobacterial Infection
Mycobacterium abscessus abscessus infection, Respiratory distress, Disseminated nontuberculous my... ORPHA:411703
Familial Nasal Acilia
Respiratory distress, Recurrent upper respiratory tract infections, Dyspnea ORPHA:922
Recurrent Respiratory Papillomatosis
Recurrent upper respiratory tract infections, Recurrent pneumonia, Failure to thrive, Respiratory... ORPHA:60032
Muscular Hypertonia, Lethal
Respiratory distress OMIM:254120
Myopathy, Congenital, With Fiber-Type Disproportion, X-Linked
Respiratory distress, Decreased body weight OMIM:300580
Cardiomyopathy-Hypotonia-Lactic Acidosis Syndrome
Respiratory distress, Failure to thrive ORPHA:91130
Chronic Pneumonitis Of Infancy
Intercostal retractions, Failure to thrive, Respiratory distress, Tachypnea, Hyperventilation ORPHA:91359
Intellectual Developmental Disorder With Speech Delay And Axonal Peripheral Neuropathy
Respiratory distress OMIM:619099
Myasthenic Syndrome, Congenital, 6, Presynaptic
Respiratory distress, Apneic episodes precipitated by illness, fatigue, stress, Sudden episodic a... OMIM:254210
Developmental And Epileptic Encephalopathy 30
Respiratory distress OMIM:616341
Pleural Mesothelioma
Respiratory distress, Dyspnea, Weight loss ORPHA:50251
Cardiomyopathy, Dilated, 1Gg
Respiratory distress OMIM:613642
Respiratory Distress Syndrome In Premature Infants
Respiratory distress, Tachypnea, Dyspnea OMIM:267450
Mitochondrial Dna Depletion Syndrome 8A (Encephalomyopathic Type With Renal Tubulopathy)
Respiratory distress, Cachexia, Weight loss, Failure to thrive OMIM:612075
Myasthenic Syndrome, Congenital, 4A, Slow-Channel
Respiratory distress, Apneic episodes precipitated by illness, fatigue, stress, Sudden episodic a... OMIM:605809
Perching Syndrome
Respiratory distress OMIM:617055
Nipah Virus Disease
Respiratory distress, Recurrent pharyngitis, Infectious encephalitis ORPHA:99825
Congenital Disorder Of Glycosylation, Type Iy
Respiratory distress, Failure to thrive OMIM:300934
Congenital Lobar Emphysema
Respiratory distress ORPHA:1928
Short Chain Acyl-Coa Dehydrogenase Deficiency
Respiratory distress, Failure to thrive ORPHA:26792
Neuronopathy, Distal Hereditary Motor, Autosomal Recessive 6
Respiratory distress, Recurrent acute respiratory tract infection, Paradoxical respiration OMIM:620011
Lethal Osteosclerotic Bone Dysplasia
Respiratory distress, Dyspnea ORPHA:1832
Laryngomalacia
Respiratory distress OMIM:150280
Severe X-Linked Mitochondrial Encephalomyopathy
Respiratory distress ORPHA:238329
Bronchopulmonary Dysplasia
Respiratory distress, Dyspnea, Central apnea, Small for gestational age ORPHA:70589
Laryngotracheal Angioma
Respiratory distress, Apnea, Intercostal retractions ORPHA:137935
Mitochondrial Dna Depletion Syndrome, Myopathic Form
Respiratory distress, Failure to thrive in infancy, Recurrent pneumonia ORPHA:254875
Inhalational Anthrax
Respiratory distress, Dyspnea, Sepsis ORPHA:247257
Congenital Myopathy 10A, Severe Variant
Respiratory distress, Failure to thrive OMIM:614399
Combined Oxidative Phosphorylation Deficiency 30
Respiratory distress, Failure to thrive OMIM:616974
Idiopathic Neonatal Atrial Flutter
Respiratory distress, Tachypnea, Large for gestational age ORPHA:45452
X-Linked Centronuclear Myopathy
Respiratory distress, Recurrent respiratory infections ORPHA:596
Acute Lung Injury
Respiratory distress, Tachypnea, Dyspnea, Sepsis ORPHA:178320
Neurodevelopmental Disorder With Spastic Quadriplegia And Brain Abnormalities With Or Without Seizures
Respiratory distress OMIM:617977
Myopathy, Lactic Acidosis, And Sideroblastic Anemia 2
Respiratory distress, Failure to thrive OMIM:613561
Malaria
Respiratory distress ORPHA:673
Hereditary Pulmonary Alveolar Proteinosis
Respiratory distress, Failure to thrive in infancy, Tachypnea ORPHA:264675
Vitamin B12-Unresponsive Methylmalonic Acidemia Type Mut0
Respiratory distress, Sepsis ORPHA:289916
Developmental And Epileptic Encephalopathy 68
Respiratory distress, Failure to thrive OMIM:618201
Stt3B-Cdg
Respiratory distress, Failure to thrive ORPHA:370924
Chitayat Syndrome
Respiratory distress, Recurrent respiratory infections OMIM:617180
Ciliary Dyskinesia, Primary, 2
Respiratory distress, Recurrent respiratory infections OMIM:606763
Coenzyme Q10 Deficiency, Primary, 8
Respiratory distress, Small for gestational age OMIM:616733
Congenital Disorder Of Glycosylation, Type Ix
Respiratory distress, Failure to thrive OMIM:615597
Imperforate Oropharynx-Costovertebral Anomalies Syndrome
Respiratory distress, Recurrent respiratory infections, Dyspnea ORPHA:2759
Congenital Laryngeal Web
Respiratory distress ORPHA:2374
Mitochondrial Pyruvate Carrier Deficiency
Respiratory distress OMIM:614741
Paternal 20Q13.2Q13.3 Microdeletion Syndrome
Respiratory distress, Failure to thrive ORPHA:261304
Auriculocondylar Syndrome 2A
Respiratory distress, Apnea OMIM:614669
Severe Acute Respiratory Syndrome
Respiratory distress, Dyspnea ORPHA:140896
Progressive Supranuclear Palsy-Parkinsonism Syndrome
Respiratory distress ORPHA:240085
Rnf13-Related Severe Early-Onset Epileptic Encephalopathy
Respiratory distress, Sepsis, Failure to thrive ORPHA:544503
Stuve-Wiedemann Syndrome 2
Respiratory distress OMIM:619751
Infant Acute Respiratory Distress Syndrome
Tachypnea, Nasal flaring, Sepsis ORPHA:70587
Anaplastic Thyroid Carcinoma
Respiratory distress, Dyspnea, Weight loss ORPHA:142
Myopathy And Diabetes Mellitus
Respiratory distress ORPHA:2596
Lethal Recessive Chondrodysplasia
Respiratory distress ORPHA:1423
Staphylococcal Necrotizing Pneumonia
Sepsis, Respiratory distress, Tachypnea, Severe infection, Dyspnea ORPHA:36238
Nasolacrimal Duct Cyst
Recurrent infections, Intercostal retractions, Paroxysmal dyspnea, Episodic respiratory distress ORPHA:141083
Choanal Atresia
Respiratory distress, Recurrent respiratory infections ORPHA:137914
Holocarboxylase Synthetase Deficiency
Respiratory distress, Tachypnea, Weight loss ORPHA:79242
Cryptogenic Organizing Pneumonia
Respiratory distress, Dyspnea, Weight loss ORPHA:1302
Diaphanospondylodysostosis
Respiratory distress ORPHA:66637
Vitamin B12-Unresponsive Methylmalonic Acidemia Type Mut-
Respiratory distress, Failure to thrive ORPHA:79312
Folinic Acid-Responsive Seizures
Respiratory distress, Apnea ORPHA:79097
Mitochondrial Myopathy With Reversible Cytochrome C Oxidase Deficiency
Respiratory distress ORPHA:254864
Tularemia
Respiratory distress, Meningitis, Brain abscess ORPHA:3392
Congenital Muscular Dystrophy With Intellectual Disability And Severe Epilepsy
Respiratory distress, Recurrent respiratory infections, Failure to thrive ORPHA:329178
Pomt1-Related Limb-Girdle Muscular Dystrophy R11
Respiratory distress, Dyspnea ORPHA:86812
Avian Influenza
Sepsis, Respiratory distress, Infectious encephalitis, Tachypnea, Dyspnea, Meningitis ORPHA:454836
Progressive Supranuclear Palsy-Corticobasal Syndrome
Respiratory distress ORPHA:240103
Surfactant Metabolism Dysfunction, Pulmonary, 2
Recurrent pneumonia, Failure to thrive, Respiratory distress, Tachypnea, Dyspnea OMIM:610913
N-Acetylglutamate Synthase Deficiency
Respiratory distress, Tachypnea, Failure to thrive OMIM:237310
Congenital Disorder Of Glycosylation, Type Ie
Respiratory distress, Failure to thrive OMIM:608799
Congenital Disorder Of Glycosylation, Type Iu
Respiratory distress OMIM:615042
Homocystinuria-Megaloblastic Anemia, Cblg Complementation Type
Respiratory distress, Failure to thrive OMIM:250940
Biotinidase Deficiency
Recurrent viral infections, Recurrent candida infections, Respiratory distress, Apnea, Recurrent ... ORPHA:79241
Thyroid Lymphoma
Respiratory distress, Dyspnea ORPHA:97285
Neurogenic Arthrogryposis Multiplex Congenita
Respiratory distress ORPHA:1143
Primary Dystonia, Dyt4 Type
Respiratory distress, Eunuchoid habitus ORPHA:98805
Severe Neonatal Hypotonia-Seizures-Encephalopathy Syndrome Due To 5Q31.3 Microdeletion
Respiratory distress, Recurrent pneumonia, Apnea, Hypoventilation ORPHA:314655
Congenital Diaphragmatic Hernia
Respiratory distress ORPHA:2140
Hyperammonemia Due To N-Acetylglutamate Synthase Deficiency
Respiratory distress, Failure to thrive ORPHA:927
Brown-Vialetto-Van Laere Syndrome 1
Respiratory distress, Nocturnal hypoventilation, Dyspnea, Recurrent respiratory infections OMIM:211530
Congenital Disorder Of Glycosylation, Type Ig
Recurrent upper respiratory tract infections, Recurrent pneumonia, Failure to thrive, Respiratory... OMIM:607143
Odontochondrodysplasia 1
Respiratory distress, Recurrent respiratory infections OMIM:184260
Carnitine Deficiency, Systemic Primary
Respiratory distress, Failure to thrive OMIM:212140
Renin-Angiotensin-Aldosterone System-Blocker-Induced Angioedema
Respiratory distress ORPHA:100057
Oromandibular Dystonia
Respiratory distress, Weight loss ORPHA:93958
Infantile Krabbe Disease
Respiratory distress, Cachexia, Failure to thrive, Recurrent infections ORPHA:206436
Shwachman-Diamond Syndrome 1
Respiratory distress, Recurrent infections, Small for gestational age, Failure to thrive OMIM:260400
Sepsis In Premature Infants
Invasive fungal infection, Decreased body weight, Neonatal sepsis, Severe infection, Dyspnea, Men... ORPHA:90051
Surfactant Metabolism Dysfunction, Pulmonary, 3
Failure to thrive, Respiratory distress, Apnea, Tachypnea, Exertional dyspnea, Dyspnea OMIM:610921
Congenital Pulmonary Lymphangiectasia
Respiratory distress ORPHA:2414
Choreoathetosis And Congenital Hypothyroidism With Or Without Pulmonary Dysfunction
Respiratory distress, Tachypnea, Recurrent respiratory infections OMIM:610978
Tetrasomy 5P
Respiratory distress, Recurrent respiratory infections, Failure to thrive ORPHA:3309
Muscular Dystrophy, Limb-Girdle, Autosomal Recessive 28
Respiratory distress OMIM:620375
Encephalopathy, Acute, Infection-Induced, Susceptibility To, 9
Hypopnea, Failure to thrive, Respiratory distress, Apnea, Recurrent lower respiratory tract infec... OMIM:618426
Neurodevelopmental Disorder With Hypotonia, Facial Dysmorphism, And Brain Abnormalities
Respiratory distress, Recurrent respiratory infections OMIM:619383
Combined Oxidative Phosphorylation Deficiency 19
Respiratory distress, Failure to thrive OMIM:615595
Acquired Methemoglobinemia
Respiratory distress, Dyspnea ORPHA:464453
Lissencephaly Syndrome, Norman-Roberts Type
Respiratory distress ORPHA:89844
Congenital Hypothyroidism Due To Maternal Intake Of Antithyroid Drugs
Respiratory distress, Large for gestational age ORPHA:226313
Hypoglossia With Situs Inversus
Respiratory distress OMIM:612776
Congenital Enterovirus Infection
Respiratory distress, Meningitis, Sepsis, Infectious encephalitis ORPHA:292
Multiple Mitochondrial Dysfunctions Syndrome 2 With Hyperglycinemia
Respiratory distress, Tachypnea OMIM:614299
Mitochondrial Complex I Deficiency, Nuclear Type 37
Respiratory distress, Failure to thrive OMIM:619272
Fructose-1,6-Bisphosphatase Deficiency
Respiratory distress, Episodic tachypnea, Intermittent hyperventilation, Apneic episodes in infan... ORPHA:348
Bacterial Toxic-Shock Syndrome
Sepsis, Severe viral infection, Recurrent urinary tract infections, Respiratory distress, Infecti... ORPHA:36234
Very Long Chain Acyl-Coa Dehydrogenase Deficiency
Respiratory distress, Episodic tachypnea, Obesity, Tachypnea, Overweight, Small for gestational age ORPHA:26793
Odontochondrodysplasia
Respiratory distress ORPHA:166272
Oculocerebrofacial Syndrome, Kaufman Type
Respiratory distress, Dyspnea, Failure to thrive ORPHA:2707
Kniest Dysplasia
Respiratory distress, Recurrent otitis media OMIM:156550
Achondroplasia, Severe, With Developmental Delay And Acanthosis Nigricans
Respiratory distress, Recurrent otitis media, Central apnea, Brain abscess OMIM:616482
Infantile-Onset X-Linked Spinal Muscular Atrophy
Respiratory distress ORPHA:1145
Slc35A1-Cdg
Respiratory distress ORPHA:238459
Microlissencephaly-Micromelia Syndrome
Respiratory distress, Failure to thrive ORPHA:50810
Mucopolysaccharidosis-Plus Syndrome
Recurrent pneumonia, Sepsis, Respiratory distress, Recurrent bronchopulmonary infections, Recurre... OMIM:617303
Synaptic Congenital Myasthenic Syndromes
Respiratory distress, Recurrent lower respiratory tract infections, Exertional dyspnea, Hypoventi... ORPHA:98915
Episodic Ataxia Type 1
Respiratory distress ORPHA:37612
Immune Dysregulation-Polyendocrinopathy-Enteropathy-X-Linked Syndrome
Recurrent infections, Sepsis, Respiratory distress, Failure to thrive in infancy, Recurrent gastr... ORPHA:37042
3-Methylglutaconic Aciduria, Type Viib
Respiratory distress, Recurrent infections, Recurrent pneumonia OMIM:616271
Mitochondrial Complex Iv Deficiency, Nuclear Type 2
Respiratory distress, Irregular respiration OMIM:604377
Short-Rib Thoracic Dysplasia 16 With Or Without Polydactyly
Respiratory distress OMIM:617102
Alfadhel Syndrome
Nasal flaring OMIM:620655
Methylmalonic Aciduria Due To Methylmalonyl-Coa Mutase Deficiency
Respiratory distress, Failure to thrive OMIM:251000
Isolated Atp Synthase Deficiency
Respiratory distress ORPHA:254913
Glycogen Storage Disease Due To Glycogen Branching Enzyme Deficiency
Respiratory distress, Failure to thrive ORPHA:367
Tetanus
Respiratory distress, Tachypnea ORPHA:3299
Muscular Dystrophy, Congenital, With Or Without Seizures
Respiratory distress OMIM:620166
Myotonic Dystrophy 1
Respiratory distress OMIM:160900
Moebius Syndrome
Respiratory distress OMIM:157900
Restrictive Dermopathy 2
Respiratory distress OMIM:619793
Mitochondrial Complex Iv Deficiency, Nuclear Type 1
Respiratory distress, Exertional dyspnea, Failure to thrive OMIM:220110
Pachyonychia Congenita
Respiratory distress, Failure to thrive ORPHA:2309
Mercury Poisoning
Respiratory distress, Dyspnea ORPHA:330021
Farber Disease
Respiratory distress, Recurrent upper respiratory tract infections, Failure to thrive ORPHA:333
Nocardiosis
Unusual CNS infection, Sepsis, Brain abscess, Respiratory distress, Infectious encephalitis, Weig... ORPHA:31204
Toxic Epidermal Necrolysis
Respiratory distress, Recurrent respiratory infections, Weight loss, Sepsis ORPHA:537
Brain-Lung-Thyroid Syndrome
Respiratory distress, Recurrent pneumonia, Failure to thrive, Recurrent respiratory infections ORPHA:209905
Chronic Recurrent Multifocal Osteomyelitis 2, With Periostitis And Pustulosis
Respiratory distress, Failure to thrive in infancy OMIM:612852
Meconium Aspiration Syndrome
Respiratory distress ORPHA:70588
Q Fever
Unusual infection, Respiratory distress, Infectious encephalitis, Weight loss, Meningitis ORPHA:781
Agnathia-Otocephaly Complex
Respiratory distress OMIM:202650
Short-Rib Thoracic Dysplasia 19 With Or Without Polydactyly
Respiratory distress OMIM:617895
Spinal muscular atrophy, type I, with congenital bone fractures
Respiratory distress OMIM:271225
Congenital Myasthenic Syndrome
Apneic episodes precipitated by illness, fatigue, stress, Recurrent respiratory infections, Sudde... ORPHA:590
Presynaptic Congenital Myasthenic Syndromes
Apneic episodes precipitated by illness, fatigue, stress, Recurrent respiratory infections, Sudde... ORPHA:98914
Craniofaciofrontodigital Syndrome
Respiratory distress, Large for gestational age, Dyspnea ORPHA:363705
Mgat2-Cdg
Respiratory distress, Failure to thrive, Recurrent upper and lower respiratory tract infections ORPHA:79329
Myotubular Myopathy With Abnormal Genital Development
Respiratory distress OMIM:300219
Complete Atrioventricular Septal Defect
Tachypnea, Intercostal retractions, Recurrent pneumonia, Failure to thrive ORPHA:1329
Methylmalonic Aciduria, Cblb Type
Respiratory distress, Failure to thrive OMIM:251110
Gaucher Disease, Perinatal Lethal
Respiratory distress, Apnea, Decreased body weight OMIM:608013
Diamond-Blackfan Anemia 15 With Mandibulofacial Dysostosis
Respiratory distress OMIM:606164
Japanese Encephalitis
Abnormal pattern of respiration, Respiratory distress, Infectious encephalitis, Irregular respira... ORPHA:79139
Esophageal Atresia
Respiratory distress, Failure to thrive in infancy, Episodic respiratory distress, Recurrent resp... ORPHA:1199
Achondroplasia
Respiratory distress, Recurrent otitis media OMIM:100800
Methylmalonic Aciduria, Cbla Type
Respiratory distress, Failure to thrive OMIM:251100
Cryptococcosis
Respiratory distress, Meningitis, Dyspnea, Sepsis ORPHA:1546
Intellectual Developmental Disorder, X-Linked 99, Syndromic, Female-Restricted
Respiratory distress, Recurrent respiratory infections OMIM:300968
Fatal Infantile Lactic Acidosis With Methylmalonic Aciduria
Respiratory distress, Recurrent respiratory infections, Apnea, Failure to thrive ORPHA:17
Osteogenesis Imperfecta, Type X
Respiratory distress, Recurrent pneumonia OMIM:613848
Agnathia-Holoprosencephaly-Situs Inversus Syndrome
Respiratory distress ORPHA:990
Rodrigues Blindness
Nasal flaring OMIM:268320
Mogs-Cdg
Respiratory distress, Apnea, Hypoventilation ORPHA:79330
Ramos-Arroyo Syndrome
Respiratory distress, Severe failure to thrive, Decreased body weight ORPHA:1051
Neuroblastoma
Respiratory distress, Weight loss ORPHA:635
Cardiomyopathy, Familial Hypertrophic, 4
Respiratory distress, Dyspnea OMIM:115197
Diaphanospondylodysostosis
Respiratory distress OMIM:608022
Mucopolysaccharidosis-Like Syndrome With Congenital Heart Defects And Hematopoietic Disorders
Respiratory distress, Recurrent respiratory infections, Sepsis, Recurrent gastroenteritis ORPHA:505248
Platyspondylic Lethal Skeletal Dysplasia, Torrance Type
Respiratory distress OMIM:151210
Prader-Willi Syndrome Due To Translocation
Respiratory distress, Obesity, Recurrent respiratory infections ORPHA:177907
Adnp Syndrome
Respiratory distress, Recurrent upper respiratory tract infections, Truncal obesity, Recurrent ur... ORPHA:404448
Triosephosphate Isomerase Deficiency
Respiratory distress, Failure to thrive OMIM:615512
Chromosome 6Q24-Q25 Deletion Syndrome
Respiratory distress OMIM:612863
Lujo Hemorrhagic Fever
Respiratory distress, Severe viral infection ORPHA:319213
Microcephaly-Seizures-Intellectual Disability-Heart Disease Syndrome
Respiratory distress ORPHA:2519
Congenital Tracheomalacia
Recurrent upper respiratory tract infections, Intercostal retractions, Failure to thrive, Apnea, ... ORPHA:95430
Multiple Acyl-Coa Dehydrogenase Deficiency
Respiratory distress OMIM:231680
Listeriosis
Unusual CNS infection, Unusual skin infection, Sepsis, Brain abscess, Respiratory distress, Infec... ORPHA:533
Congenital Disorder Of Deglycosylation 1
Respiratory distress, Recurrent respiratory infections, Decreased body weight OMIM:615273
Severe Generalized Junctional Epidermolysis Bullosa
Sepsis, Failure to thrive, Recurrent urinary tract infections, Respiratory distress, Pyoderma, Dy... ORPHA:79404
Mandibulofacial Dysostosis, Guion-Almeida Type
Respiratory distress OMIM:610536
Pura-Related Severe Neonatal Hypotonia-Seizures-Encephalopathy Syndrome Due To A Point Mutation
Respiratory distress ORPHA:438216
Glycogen Storage Disease Due To Acid Maltase Deficiency, Infantile Onset
Respiratory distress, Failure to thrive ORPHA:308552
Alternating Hemiplegia Of Childhood
Respiratory distress, Apnea, Failure to thrive ORPHA:2131
Mitochondrial Dna-Associated Leigh Syndrome
Failure to thrive, Apnea, Episodic respiratory distress, Dyspnea, Hyperventilation ORPHA:255210
Radio-Renal Syndrome
Respiratory distress, Dyspnea ORPHA:3015
Cutis Gyrata-Acanthosis Nigricans-Craniosynostosis Syndrome
Respiratory distress ORPHA:1555
Hemorrhagic Fever-Renal Syndrome
Respiratory distress, Severe infection, Dyspnea, Decreased body weight ORPHA:340
Corpus Callosum, Agenesis Of, With Facial Anomalies And Robin Sequence
Respiratory distress OMIM:217980
Hereditary Angioedema Type 1
Respiratory distress, Dyspnea ORPHA:100050
Neurodegeneration And Seizures Due To Copper Transport Defect
Respiratory distress OMIM:620306
Auriculocondylar Syndrome
Respiratory distress ORPHA:137888
Wac-Related Facial Dysmorphism-Developmental Delay-Behavioral Abnormalities Syndrome
Recurrent infections, Obesity, Nasal flaring ORPHA:466943
Pfeiffer Syndrome Type 2
Respiratory distress ORPHA:93259
Mitochondrial Dna Depletion Syndrome 15 (Hepatocerebral Type)
Respiratory distress, Failure to thrive OMIM:617156
Lymphatic Malformation 7
Respiratory distress OMIM:617300
Spondyloepiphyseal Dysplasia Congenita
Respiratory distress OMIM:183900
Neuromuscular Oculoauditory Syndrome
Respiratory distress OMIM:618733
Pfeiffer Syndrome Type 3
Respiratory distress ORPHA:93260
Arterial Tortuosity Syndrome
Respiratory distress, Dyspnea ORPHA:3342
Thrombotic Thrombocytopenic Purpura, Hereditary
Respiratory distress OMIM:274150
Glycogen Storage Disease Due To Acid Maltase Deficiency
Respiratory distress, Exertional dyspnea, Orthopnea, Failure to thrive ORPHA:365
Meier-Gorlin Syndrome 1
Respiratory distress, Small for gestational age, Failure to thrive OMIM:224690
Scimitar Syndrome
Respiratory distress, Recurrent respiratory infections ORPHA:185
Campomelic Dysplasia
Recurrent upper respiratory tract infections, Failure to thrive, Respiratory distress, Apnea, Rec... OMIM:114290
Mitochondrial Dna Depletion Syndrome 6 (Hepatocerebral Type)
Respiratory distress, Failure to thrive OMIM:256810
Beare-Stevenson Cutis Gyrata Syndrome
Respiratory distress OMIM:123790
Coccidioidomycosis
Respiratory distress, Unusual CNS infection, Invasive fungal infection, Coccidioidal meningitis ORPHA:228123
Congenital Myopathy 22B, Severe Fetal
Respiratory distress OMIM:620369
Diamond-Blackfan Anemia 10
Respiratory distress OMIM:613309
Ear-Patella-Short Stature Syndrome
Respiratory distress, Dyspnea, Failure to thrive ORPHA:2554
Oculopharyngodistal Myopathy 1
Respiratory distress, Weight loss OMIM:164310
Hyperparathyroidism, Transient Neonatal
Respiratory distress OMIM:618188
Methylmalonic Acidemia With Homocystinuria, Type Cblc
Respiratory distress, Failure to thrive ORPHA:79282
Arboleda-Tham Syndrome
Respiratory distress, Recurrent otitis media, Recurrent respiratory infections, Recurrent urinary... OMIM:616268
Idiopathic Hypereosinophilic Syndrome
Respiratory distress, Dyspnea, Failure to thrive ORPHA:3260
B3Galt6-Related Spondylodysplastic Ehlers-Danlos Syndrome
Respiratory distress ORPHA:536467
Osteoglophonic Dysplasia
Respiratory distress, Failure to thrive OMIM:166250
Congenital Myopathy 2C, Severe Infantile, Autosomal Dominant
Respiratory distress OMIM:620278
Ethylene Glycol Poisoning
Tachypnea, Abnormal pattern of respiration, Episodic respiratory distress ORPHA:31826
Cocaine Intoxication
Respiratory distress, Hyperventilation, Tachypnea ORPHA:90068
Glycogen Storage Disease Of Heart, Lethal Congenital
Respiratory distress, Apnea OMIM:261740
Congenital Alveolar Capillary Dysplasia
Respiratory distress ORPHA:210122
Colchicine Poisoning
Respiratory distress ORPHA:31824
Rubinstein-Taybi Syndrome 1
Recurrent upper respiratory tract infections, Failure to thrive, Respiratory distress, Truncal ob... OMIM:180849
Kasabach-Merritt Phenomenon
Respiratory distress, Hypopnea ORPHA:2330
Schinzel-Giedion Syndrome
Respiratory distress, Failure to thrive in infancy, Recurrent pneumonia ORPHA:798
Isolated Arrhinia
Respiratory distress ORPHA:1134
Microphthalmia With Linear Skin Defects Syndrome
Respiratory distress, Dyspnea, Failure to thrive ORPHA:2556
Epidermolysis Bullosa, Junctional 7, With Interstitial Lung Disease And Nephrotic Syndrome
Respiratory distress, Recurrent respiratory infections OMIM:614748
Heterotaxy, Visceral, 1, X-Linked
Respiratory distress, Failure to thrive OMIM:306955
Aortic Arch Interruption
Respiratory distress, Tachypnea, Exertional dyspnea ORPHA:2299
Ectodermal Dysplasia 1, Hypohidrotic, X-Linked
Respiratory distress OMIM:305100
Gitelman Syndrome
Respiratory distress, Failure to thrive ORPHA:358
Pancreatic Hypoplasia-Diabetes-Congenital Heart Disease Syndrome
Respiratory distress, Small for gestational age, Failure to thrive ORPHA:2255
Agammaglobulinemia-Microcephaly-Craniosynostosis-Severe Dermatitis Syndrome
Respiratory distress, Failure to thrive ORPHA:83617
Cleidocranial Dysplasia 1
Respiratory distress OMIM:119600
Plague
Respiratory distress, Meningitis, Sepsis ORPHA:707
Congenital Tracheal Stenosis
Respiratory distress, Dyspnea ORPHA:141127
8Q24.3 Microdeletion Syndrome
Respiratory distress, Small for gestational age ORPHA:508488
Leptospirosis
Respiratory distress, Meningitis ORPHA:509
Congenital Total Pulmonary Venous Return Anomaly
Paroxysmal dyspnea, Respiratory distress, Apneic episodes in infancy, Exertional dyspnea, Recurre... ORPHA:99125
Eisenmenger Syndrome
Respiratory distress, Exertional dyspnea, Brain abscess ORPHA:97214
Stüve-Wiedemann Syndrome
Respiratory distress, Apnea ORPHA:3206
Metaphyseal Chondromatosis With D-2-Hydroxyglutaric Aciduria
Respiratory distress, Recurrent pneumonia, Sepsis, Failure to thrive ORPHA:99646
Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis Spectrum
Respiratory distress, Sepsis ORPHA:95455
Tuberous Sclerosis Complex
Respiratory distress ORPHA:805
X-Linked Female Restricted Facial Dysmorphism-Short Stature-Choanal Atresia-Intellectual Disability
Respiratory distress, Recurrent upper and lower respiratory tract infections ORPHA:480880
Short-Rib Thoracic Dysplasia 15 With Polydactyly
Respiratory distress OMIM:617088
Doors Syndrome
Respiratory distress ORPHA:79500
Generalized Arterial Calcification Of Infancy
Respiratory distress, Failure to thrive in infancy ORPHA:51608
Ulbright-Hodes Syndrome
Respiratory distress ORPHA:3404
Alström Syndrome
Recurrent pneumonia, Recurrent upper respiratory tract infections, Recurrent urinary tract infect... ORPHA:64
Pmm2-Cdg
Respiratory distress, Failure to thrive ORPHA:79318

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Muc4

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Muc4.

No publications found that use IMPC mice or data for Muc4.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

MGI Allele Allele Type Produced
Muc4tm1(KOMP)Wtsi Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Muc4tm1(KOMP)Mbp Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells

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